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NCT00485693 · ClinicalTrials.gov registry record · Phase 2
Dose-Ranging Study for Prolonged Postoperative Analgesia in Subject Undergoing Total Knee Arthroplasty
A Phase 2 study of Postoperative Pain, sponsored by Pacira Pharmaceuticals.
- Completed
- Registry status
- Phase 2
- Development phase
- 138
- Enrollment target
- 9
- Study locations
NCT00485693: Completed Phase 2 study of Postoperative Pain, sponsored by Pacira Pharmaceuticals.
NCT00485693 is a Phase 2 study of Postoperative Pain that has completed, run by Pacira Pharmaceuticals. The registered enrollment target is 138 participants, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (40% lower). The trial reports 9 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00485693, a Phase 2 study of Postoperative Pain, has completed, sponsored by Pacira Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 138 participants
- Enrollment target
- 9
- Study locations
Study Summary
Dose-ranging study for prolonged postoperative analgesia in subjects undergoing total knee arthroplasty
Primary Outcome
The subject's pain intensity was to be assessed with activity (NRS-A) after actively flexing the involved knee to the maximum flexion point possible. The subject was asked to respond to the following question: "On a scale of 0 to 10, where 0 = no pain and 10 = worst possible pain, how much pain did you have while bending your knee?"
Conditions Studied
Interventions
- DRUG Bupivacaine HCl
- DRUG SKY0402
Study Locations (9)
Other
- Urazova Nemocnice Brno - Brno
- Regional Hospital Kladno - Kladno
- The Hospital Trebic - Třebíč
California
- California Clinical Research, Inc. - Davis
- Accurate Clinical Trials, Inc. - Laguna Hills
Alabama
- West Alabama Research, Inc. - Birmingham
New York
- St. Luke's Roosevelt Hospital - New York
Ohio
- The Ohio State University Medical Center - Columbus
Texas
- Texas Tech University Health Science Center - Lubbock
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 138 participants |
| Start Date | 2007-06 |
| Est. Completion | 2009-08 |
| Phase | Phase 2 |
What the finished NCT00485693 record still lists
NCT00485693 is an interventional study that assigns participants to a tested intervention. The registered 138 participants enrollment target is mid-sized for trials with a published cap, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (40% lower).
The record links to 1 condition, with Postoperative Pain appearing as the primary indexed condition, and to 2 interventions - of which Bupivacaine HCl is the first listed.
NCT00485693 lists 9 locations in 6 states (Other, California, Alabama).
Frequently Asked Questions
What is clinical trial NCT00485693 about?
NCT00485693 is a clinical study titled "Dose-Ranging Study for Prolonged Postoperative Analgesia in Subject Undergoing Total Knee Arthroplasty". Dose-ranging study for prolonged postoperative analgesia in subjects undergoing total knee arthroplasty
What is the current status of trial NCT00485693?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 138 participants. The study started on 2007-06. Estimated completion is 2009-08.
What conditions does trial NCT00485693 study?
This clinical trial studies the following conditions: Postoperative Pain.
What interventions are being tested in trial NCT00485693?
The interventions under investigation include: Bupivacaine HCl (DRUG), SKY0402 (DRUG).
Who is sponsoring clinical trial NCT00485693?
This trial is sponsored by Pacira Pharmaceuticals, which has 88 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00485693 being conducted?
This trial has 9 study locations across Alabama, California, New York, Ohio, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00485693's enrollment target sits among peer trials
138 35th of 120 higher than 86 of 120 other Postoperative Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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