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RECRUITING Phase 1

A Study of BMS-986484 Alone and Combination Therapy in Participants With Advanced Solid Tumors

NCT06544655 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to assess the safety and tolerability of BMS-986484 administered alone, in combination with nivolumab in participants with advanced/metastatic solid tumors including non-small cell lung cancer (NSCLC), microsatellite stable (MSS) colorectal carcinoma (CRC), pancreatic ductal adenocarcinoma (PDAC), gastric/gastroesophageal junction adenocarcinoma (G/GEJC), and squamous cell carcinoma of the head and neck (SCCHN).

Conditions Studied

Interventions

  • DRUG Capecitabine
  • DRUG Fluorouracil
  • DRUG Oxaliplatin
  • BIOLOGICAL Nivolumab
  • DRUG BMS-986484

Study Locations (11)

Arizona

  • University of Arizona Cancer Center — Tucson

California

  • USC/Norris Comprehensive Cancer Center — Los Angeles

Michigan

  • START Midwest — Grand Rapids

South Dakota

  • Sanford Cancer Center — Sioux Falls

Texas

  • NEXT Oncology — San Antonio

New South Wales

  • St Vincent's Hospital — Darlinghurst

South Australia

  • Lyell McEwin Hospital — Elizabeth Vale

Ontario

  • Princess Margaret Cancer Centre — Toronto

Trial Details

FieldValue
Enrollment Target 213 participants
Start Date 2024-10-10
Est. Completion 2027-10-14
Phase Phase 1

Sponsor

Bristol-Myers Squibb

504 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06544655

The ClinicalTrials.gov registry entry for NCT06544655 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 213 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Bristol-Myers Squibb, which has 504 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Advanced Solid Tumors appearing as the primary indexed condition, and to 5 interventions — of which Capecitabine is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06544655 reports 11 study locations spanning 11 distinct geographic areas — top geographies include Arizona, California, Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06544655 about?

NCT06544655 is a clinical study titled "A Study of BMS-986484 Alone and Combination Therapy in Participants With Advanced Solid Tumors". The purpose of this study is to assess the safety and tolerability of BMS-986484 administered alone, in combination with nivolumab in participants with advanced/metastatic solid tumors including non-small cell lung cancer (NSCLC), microsatellite stable (MSS) colorectal carcinoma (CRC), pancreatic du...

What is the current status of trial NCT06544655?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 213 participants. The study started on 2024-10-10. Estimated completion is 2027-10-14.

What conditions does trial NCT06544655 study?

This clinical trial studies the following conditions: Advanced Solid Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06544655?

The interventions under investigation include: Capecitabine (DRUG), Fluorouracil (DRUG), Oxaliplatin (DRUG), Nivolumab (BIOLOGICAL), BMS-986484 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06544655?

This trial is sponsored by Bristol-Myers Squibb, which has 504 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06544655 being conducted?

This trial has 11 study locations across Arizona, California, Michigan, South Dakota, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial