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Effects of MEDI-522 On Disease Activity and Progression of Joint Damage in Patients With Active Rheumatoid Arthritis Suboptimally Responding to Methotrexate
NCT00069017 · View on ClinicalTrials.gov ↗
Study Summary
To compare, as a preliminary analysis, the effects of MEDI-522 versus placebo at 6 months on disease activity (ACR20) and progression of structural joint damage.
Conditions Studied
Interventions
- OTHER Placebo
- BIOLOGICAL MEDI-522
Study Locations (20)
Florida
- Arthritis and Rheumatic Disease Specialty — Aventura
- Centre for Rheumatology, Immunology & Arthritis — Fort Lauderdale
- Ocala Rheumatology Research Center — Ocala
- Sarasota Arthritis Research Center — Sarasota
Arizona
- Sun Valley Arthritis Center — Glendale
- Arizona Research & Education — Phoenix
- University of Arizona — Tucson
California
- Thornton Hospital — La Jolla
- Boling Clinical Trials — Rancho Cucamonga
- Pacific Arthritis Center Medical Group — Santa Maria
Missouri
- RIMA — St Louis
- Arthritis Consultants, Inc. — St Louis
Oklahoma
- Health Research Institute — Oklahoma City
- Lynn Health Science Institute — Oklahoma City
Alabama
- The University of Alabama at Birmingham — Birmingham
Arkansas
- Fayetteville Diagnostic Clinic, Ltd. — Fayetteville
Georgia
- Sanford S. Hartman — Decatur
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2003-09 |
| Est. Completion | 2006-04 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00069017
The ClinicalTrials.gov registry entry for NCT00069017 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is MedImmune, which has 55 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Rheumatoid Arthritis appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00069017 reports 20 study locations spanning 11 distinct geographic areas — top geographies include Florida, Arizona, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00069017 about?
NCT00069017 is a clinical study titled "Effects of MEDI-522 On Disease Activity and Progression of Joint Damage in Patients With Active Rheumatoid Arthritis Suboptimally Responding to Methotrexate". To compare, as a preliminary analysis, the effects of MEDI-522 versus placebo at 6 months on disease activity (ACR20) and progression of structural joint damage.
What is the current status of trial NCT00069017?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 300 participants. The study started on 2003-09. Estimated completion is 2006-04.
What conditions does trial NCT00069017 study?
This clinical trial studies the following conditions: Rheumatoid Arthritis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00069017?
The interventions under investigation include: Placebo (OTHER), MEDI-522 (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00069017?
This trial is sponsored by MedImmune, which has 55 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00069017 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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