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NCT00025675 · ClinicalTrials.gov registry record · Phase 2

Gefitinib in Treating Patients With Recurrent or Progressive CNS Tumors

A Phase 2 study of Brain and Central Nervous System Tumors, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Completed
Registry status
Phase 2
Development phase
105
Enrollment target
12
Study locations

NCT00025675 is a Phase 2 study of Brain and Central Nervous System Tumors that has completed, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 105 participants, below the 181-participant average among 45 other Brain and Central Nervous System Tumors trials with a reported enrollment target (42% lower). The trial reports 12 study locations across 8 states.

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The verdict

NCT00025675, a Phase 2 study of Brain and Central Nervous System Tumors, has completed, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

COMPLETED
Registry status
Phase 2
Development phase
105 participants
Enrollment target
12
Study locations

Study Summary

RATIONALE: Biological therapies such as gefitinib may interfere with the growth of tumor cells and slow the growth of CNS tumors. PURPOSE: Phase II trial to study the effectiveness of gefitinib in treating patients who have recurrent or progressive CNS tumors.

Interventions

  • DRUG gefitinib

Study Locations (12)

Texas

  • Simmons Cancer Center at University of Texas Southwestern Medical Center - Dallas - Dallas
  • M.D. Anderson Cancer Center at University of Texas - Houston
  • University of Texas Health Science Center at San Antonio - San Antonio

California

  • Jonsson Comprehensive Cancer Center at UCLA - Los Angeles
  • UCSF Comprehensive Cancer Center - San Francisco

Maryland

  • Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support - Bethesda
  • NCI - Neuro-Oncology Branch - Bethesda

Massachusetts

  • Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute - Boston

Michigan

  • University of Michigan Comprehensive Cancer Center - Ann Arbor

New York

  • Memorial Sloan-Kettering Cancer Center - New York

Pennsylvania

  • Hillman Cancer Center at University of Pittsburgh Cancer Institute - Pittsburgh

Wisconsin

  • University of Wisconsin Comprehensive Cancer Center - Madison

Trial Details

FieldValue
Enrollment Target 105 participants
Start Date 2001-10-09
Est. Completion 2010-01-02
Phase Phase 2

What the Registry Record Tells You About NCT00025675

The ClinicalTrials.gov registry entry for NCT00025675 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 105 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 181-participant average among 45 other Brain and Central Nervous System Tumors trials with a reported enrollment target (42% lower). The listed sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Brain and Central Nervous System Tumors appearing as the primary indexed condition, and to 1 intervention - of which gefitinib is the first listed.

NCT00025675 reports 12 study locations spanning 8 distinct geographic areas - top geographies include Texas, California, Maryland.

Frequently Asked Questions

What is clinical trial NCT00025675 about?

NCT00025675 is a clinical study titled "Gefitinib in Treating Patients With Recurrent or Progressive CNS Tumors". RATIONALE: Biological therapies such as gefitinib may interfere with the growth of tumor cells and slow the growth of CNS tumors. PURPOSE: Phase II trial to study the effectiveness of gefitinib in treating patients who have recurrent or progressive CNS tumors.

What is the current status of trial NCT00025675?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 105 participants. The study started on 2001-10-09. Estimated completion is 2010-01-02.

What conditions does trial NCT00025675 study?

This clinical trial studies the following conditions: Brain and Central Nervous System Tumors.

What interventions are being tested in trial NCT00025675?

The interventions under investigation include: gefitinib (DRUG).

Who is sponsoring clinical trial NCT00025675?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00025675 being conducted?

This trial has 12 study locations across California, Maryland, Massachusetts, Michigan, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.