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Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Anaplastic Astrocytoma
NCT00003621 · View on ClinicalTrials.gov ↗
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining more than one drug with radiation therapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus radiation therapy in treating patients who have newly diagnosed anaplastic astrocytoma.
Conditions Studied
Interventions
- DRUG cisplatin
- DRUG etoposide
- RADIATION radiation therapy
- DRUG carmustine
Study Locations (18)
Minnesota
- CCOP - Duluth — Duluth
- Mayo Clinic Cancer Center — Rochester
- CentraCare Clinic — Saint Cloud
- CCOP - Metro-Minnesota — Saint Louis Park
Iowa
- CCOP - Cedar Rapids Oncology Project — Cedar Rapids
- CCOP - Iowa Oncology Research Association — Des Moines
- Siouxland Hematology-Oncology — Sioux City
North Dakota
- Quain & Ramstad Clinic, P.C. — Bismarck
- Altru Health Systems — Grand Forks
South Dakota
- Rapid City Regional Hospital — Rapid City
- CCOP - Sioux Community Cancer Consortium — Sioux Falls
Arizona
- CCOP - Scottsdale Oncology Program — Scottsdale
Illinois
- CCOP - Illinois Oncology Research Association — Peoria
Kansas
- CCOP - Wichita — Wichita
Louisiana
- CCOP - Ochsner — New Orleans
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 1999-02 |
| Est. Completion | 2005-07 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00003621
The ClinicalTrials.gov registry entry for NCT00003621 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 29 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Alliance for Clinical Trials in Oncology, which has 147 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Brain and Central Nervous System Tumors appearing as the primary indexed condition, and to 4 interventions — of which cisplatin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00003621 reports 18 study locations spanning 11 distinct geographic areas — top geographies include Minnesota, Iowa, North Dakota. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00003621 about?
NCT00003621 is a clinical study titled "Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Anaplastic Astrocytoma". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining more than one drug with radiation therapy may kill more tumor cells. PURPOSE: Phase II trial to study th...
What is the current status of trial NCT00003621?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 29 participants. The study started on 1999-02. Estimated completion is 2005-07.
What conditions does trial NCT00003621 study?
This clinical trial studies the following conditions: Brain and Central Nervous System Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00003621?
The interventions under investigation include: cisplatin (DRUG), etoposide (DRUG), radiation therapy (RADIATION), carmustine (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00003621?
This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 147 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00003621 being conducted?
This trial has 18 study locations across Arizona, Illinois, Iowa, Kansas, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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