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NCT00002814 · ClinicalTrials.gov registry record · Phase 2

Combination Chemotherapy for Patients With Brain Cancer

A Phase 2 study of Brain and Central Nervous System Tumors, sponsored by Dartmouth-Hitchcock Medical Center.

Completed
Registry status
Phase 2
Development phase
20
Enrollment target
1
Study location

NCT00002814 is a Phase 2 study of Brain and Central Nervous System Tumors that has completed, run by Dartmouth-Hitchcock Medical Center. The registered enrollment target is 20 participants, below the 183-participant average among 45 other Brain and Central Nervous System Tumors trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00002814, a Phase 2 study of Brain and Central Nervous System Tumors, has completed, sponsored by Dartmouth-Hitchcock Medical Center.

COMPLETED
Registry status
Phase 2
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy using paclitaxel and topotecan, plus G-CSF, in treating patients with glioblastoma multiforme or anaplastic astrocytoma that is refractory or recurrent.

Interventions

  • DRUG paclitaxel
  • BIOLOGICAL filgrastim
  • DRUG topotecan hydrochloride

Study Locations (1)

New Hampshire

  • Dartmouth-Hitchcock Medical Center - Lebanon

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 1996-08
Est. Completion 2001-12
Phase Phase 2

Sponsor

Dartmouth-Hitchcock Medical Center

427 total trials

What the Registry Record Tells You About NCT00002814

The ClinicalTrials.gov registry entry for NCT00002814 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 183-participant average among 45 other Brain and Central Nervous System Tumors trials with a reported enrollment target (89% lower). The listed sponsor is Dartmouth-Hitchcock Medical Center, which has 427 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Brain and Central Nervous System Tumors appearing as the primary indexed condition, and to 3 interventions - of which paclitaxel is the first listed.

NCT00002814 reports 1 study location spanning 1 distinct geographic area - top geographies include New Hampshire.

Frequently Asked Questions

What is clinical trial NCT00002814 about?

NCT00002814 is a clinical study titled "Combination Chemotherapy for Patients With Brain Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy using paclitaxel and topotecan, plus G-CSF, ...

What is the current status of trial NCT00002814?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 1996-08. Estimated completion is 2001-12.

What conditions does trial NCT00002814 study?

This clinical trial studies the following conditions: Brain and Central Nervous System Tumors.

What interventions are being tested in trial NCT00002814?

The interventions under investigation include: paclitaxel (DRUG), filgrastim (BIOLOGICAL), topotecan hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00002814?

This trial is sponsored by Dartmouth-Hitchcock Medical Center, which has 427 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00002814 being conducted?

This trial has 1 study location across New Hampshire. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.