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NCT06727110 · ClinicalTrials.gov registry record · NA
Polymer Induced Liquid Precursor (PILP) in Adults in With Dentin Caries
A NA study of Dental Caries, sponsored by University of California, San Francisco.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT06727110: Recruiting NA study of Dental Caries, sponsored by University of California, San Francisco.
NCT06727110 is a NA study of Dental Caries that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 30 participants, below the 721-participant average among 30 other Dental Caries trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06727110, a NA study of Dental Caries, is actively recruiting participants, sponsored by University of California, San Francisco.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to learn if polymer-induced liquid precursor (PILP) can be used safely to treat dentin caries (cavities) in adults. The main question it aims to answer is: Is PILP (conditioner or liner) safe in adult teeth with dental caries? Researchers will compare PILP to a placebo (a look-alike substance that contains no drug) to see if PILP safely treats cavities in teeth. Participants will: 1) Have PILP or placebo applied to their tooth prior to the placement of a filling in the tooth, 2) Complete two telephone calls within three months of filling placement and 3) Visit the clinic at three months and six months after the placement of the filling.
Primary Outcome
Tooth vitality (pulpal response) after intervention.
Conditions Studied
Interventions
- DEVICE PILP Cement
- DEVICE PILP Conditioner
Study Locations (1)
California
- University of California San Francisco, School of Dentistry - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-02-01 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT06727110 shows while recruiting
NCT06727110 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 721-participant average among 30 other Dental Caries trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Dental Caries appearing as the primary indexed condition, and to 2 interventions - of which PILP Cement is the first listed.
NCT06727110 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06727110 about?
NCT06727110 is a clinical study titled "Polymer Induced Liquid Precursor (PILP) in Adults in With Dentin Caries". The goal of this clinical trial is to learn if polymer-induced liquid precursor (PILP) can be used safely to treat dentin caries (cavities) in adults. The main question it aims to answer is: Is PILP (conditioner or liner) safe in adult teeth with dental caries? Researchers will compare PILP to a pla...
What is the current status of trial NCT06727110?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2025-02-01. Estimated completion is 2026-12-31.
What conditions does trial NCT06727110 study?
This clinical trial studies the following conditions: Dental Caries.
What interventions are being tested in trial NCT06727110?
The interventions under investigation include: PILP Cement (DEVICE), PILP Conditioner (DEVICE).
Who is sponsoring clinical trial NCT06727110?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06727110 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Dental Caries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06727110's enrollment target sits among peer trials
30 25th of 30 higher than 4 of 30 other Dental Caries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dental Caries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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