Xenon Pharmaceuticals
Trial Pipeline
A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)
NCT07172516
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
NCT07076407
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
NCT06775379
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
NCT05716100
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
NCT05667142
A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy
NCT03796962
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures
NCT05614063
Safety and Efficacy Study of XPF-001 to Treat Pain Following Wisdom Tooth Extraction
NCT00954356
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 2 |
| Phase 3 | 6 |
What the Pipeline for Xenon Pharmaceuticals Shows
According to the ClinicalTrials.gov registry, Xenon Pharmaceuticals is linked to 8 US clinical trials across every stage of research activity. Of those, 5 studies are currently recruiting — about 63% of the sponsor's indexed portfolio — and 2 are already marked complete, representing roughly 25% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for Xenon Pharmaceuticals reports 6 late-stage studies (Phase 3 and Phase 4 combined) and 2 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for Xenon Pharmaceuticals is Focal Onset Seizures with 2 linked trials, and 8 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.