Xenon Pharmaceuticals

13 total trials 5 currently recruiting 5 completed

Xenon Pharmaceuticals sponsors 13 registered US clinical trials on ClinicalTrials.gov, 5 of them currently recruiting, and 5 completed. 8 of these trials are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Focal Onset Seizures, with 2 trials.

Trial Pipeline

13 total, page 1 of 1

RECRUITING Phase 3

A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)

NCT07172516

RECRUITING Phase 3

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

NCT07076407

RECRUITING Phase 3

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

NCT06775379

RECRUITING Phase 3

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

NCT05716100

RECRUITING Phase 3

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

NCT05667142

ACTIVE NOT RECRUITING Phase 2

A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy

NCT03796962

COMPLETED Phase 3

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures

NCT05614063

COMPLETED Phase 2

A Study to Evaluate the Safety, Tolerability and Efficacy of XEN1101 in Major Depressive Disorder

NCT05376150

TERMINATED Phase 3

An Open-Label Extension of the Study XEN496 (Ezogabine) in Children With KCNQ2-DEE

NCT04912856

TERMINATED Phase 3

XEN496 (Ezogabine) in Children With KCNQ2 Developmental and Epileptic Encephalopathy

NCT04639310

COMPLETED Phase 1

Phase 2a, Exploratory Study to Evaluate the Safety, Efficacy, Tolerability and Pharmacokinetics of XPF-002 in Patients With Primary/Inherited Erythromelalgia

NCT01486446

COMPLETED Phase 2

A Crossover Study to Evaluate the Safety, Tolerability and Efficacy of XPF-002 in Subjects With Postherpetic Neuralgia (PHN)

NCT01195636

COMPLETED Phase 2

Safety and Efficacy Study of XPF-001 to Treat Pain Following Wisdom Tooth Extraction

NCT00954356

What the Pipeline for Xenon Pharmaceuticals Shows

According to the ClinicalTrials.gov registry, Xenon Pharmaceuticals is linked to 13 US clinical trials across every stage of research activity. Of those, 5 studies are currently recruiting, about 38% of the sponsor's indexed portfolio, and 5 are already marked complete, representing roughly 38% of the total.

The phase mix for Xenon Pharmaceuticals reports 8 late-stage studies (Phase 3 and Phase 4 combined) and 5 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Xenon Pharmaceuticals is Focal Onset Seizures with 2 linked trials, and 8 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.