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NCT07446439 · ClinicalTrials.gov registry record · Phase 3

A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use

A Phase 3 study, sponsored by Vanda Pharmaceuticals.

Recruiting
Registry status
Phase 3
Development phase
280
Enrollment target

NCT07446439 is a Phase 3 study that is actively recruiting participants, run by Vanda Pharmaceuticals. The registered enrollment target is 280 participants.

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The verdict

NCT07446439, a Phase 3 study, is actively recruiting participants, sponsored by Vanda Pharmaceuticals.

RECRUITING
Registry status
Phase 3
Development phase
280 participants
Enrollment target

Study Summary

The goal of this study is to measure the effects of using Tradipitant to treat nausea and vomiting induced by GLP-1R agonist use in adults with class I or class II obesity, or adults who are overweight with at least one weight-related condition. The study is placebo-controlled with two treatment arms.

Interventions

  • DRUG Placebo
  • DRUG Tradipitant

Trial Details

FieldValue
Enrollment Target 280 participants
Start Date 2026-03-27
Est. Completion 2026-12-01
Phase Phase 3

Sponsor

Vanda Pharmaceuticals

68 total trials

What the Registry Record Tells You About NCT07446439

The ClinicalTrials.gov registry entry for NCT07446439 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 280 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanda Pharmaceuticals, which has 68 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT07446439 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07446439 about?

NCT07446439 is a clinical study titled "A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use". The goal of this study is to measure the effects of using Tradipitant to treat nausea and vomiting induced by GLP-1R agonist use in adults with class I or class II obesity, or adults who are overweight with at least one weight-related condition. The study is placebo-controlled with two treatment arm...

What is the current status of trial NCT07446439?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 280 participants. The study started on 2026-03-27. Estimated completion is 2026-12-01.

What interventions are being tested in trial NCT07446439?

The interventions under investigation include: Placebo (DRUG), Tradipitant (DRUG).

Who is sponsoring clinical trial NCT07446439?

This trial is sponsored by Vanda Pharmaceuticals, which has 68 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.