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NCT05903924 · ClinicalTrials.gov registry record · Phase 3

Motion Serifos: A Study to Investigate the Efficacy of Tradipitant in Participants Affected by Motion Sickness

A Phase 3 study, sponsored by Vanda Pharmaceuticals.

Completed
Registry status
Phase 3
Development phase
316
Enrollment target

NCT05903924: Completed Phase 3 study, sponsored by Vanda Pharmaceuticals.

NCT05903924 is a Phase 3 study that has completed, run by Vanda Pharmaceuticals. The registered enrollment target is 316 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (59% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05903924, a Phase 3 study, has completed, sponsored by Vanda Pharmaceuticals.

COMPLETED
Registry status
Phase 3
Development phase
316 participants
Enrollment target

Study Summary

A multi-center, randomized, double-blind, placebo-controlled study to investigate the efficacy of tradipitant in participants affected by motion sickness during travel

Primary Outcome

Prevention of vomiting measured by Vomiting Assessment (VA) score. The VA is a 1-item questionnaire to objectively measure the incidence of emesis. Participants will indicate whether or not they have vomited.

Interventions

  • DRUG Placebo
  • DRUG Tradipitant

Trial Details

FieldValue
Enrollment Target 316 participants
Start Date 2023-09-09
Est. Completion 2024-04-24
Phase Phase 3
Vanda Pharmaceuticals

68 total trials

What the finished NCT05903924 record still lists

NCT05903924 is an interventional study that assigns participants to a tested intervention. The registered 316 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (59% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT05903924 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05903924 about?

NCT05903924 is a clinical study titled "Motion Serifos: A Study to Investigate the Efficacy of Tradipitant in Participants Affected by Motion Sickness". A multi-center, randomized, double-blind, placebo-controlled study to investigate the efficacy of tradipitant in participants affected by motion sickness during travel

What is the current status of trial NCT05903924?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 316 participants. The study started on 2023-09-09. Estimated completion is 2024-04-24.

What interventions are being tested in trial NCT05903924?

The interventions under investigation include: Placebo (DRUG), Tradipitant (DRUG).

Who is sponsoring clinical trial NCT05903924?

This trial is sponsored by Vanda Pharmaceuticals, which has 68 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05903924's enrollment target sits among peer trials

316 1090th of 2000 higher than 909 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05903924, the US trial registry maintained by the National Library of Medicine. NCT05903924 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.