Otsuka Pharmaceutical Development & Commercialization

221 total trials 8 currently recruiting 186 completed

Otsuka Pharmaceutical Development & Commercialization sponsors 221 registered US clinical trials on ClinicalTrials.gov, 8 of them currently recruiting, and 186 completed. 119 of these trials are in Phase 3-4 (later-stage) and 97 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Schizophrenia, with 12 trials.

Trial Pipeline

221 total, page 4 of 5

COMPLETED Phase 2

Dasatinib Added to Gemcitabine for Subjects With Locally-advanced Pancreatic Cancer

NCT01395017

COMPLETED Phase 1

Trial Evaluating OPC-34712 in Subjects With Normal Renal Function and Renally Impaired Subjects

NCT01289080

COMPLETED Phase 1

A Study Evaluating the of OPC-34712 in Subjects With Normal Hepatic Function and Hepatically Impaired Subjects

NCT01299454

TERMINATED Phase 3

Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)

NCT01111565

COMPLETED Phase 2

Dose-finding Study of New Tolvaptan Formulation in Subjects With ADPKD

NCT01210560

TERMINATED Phase 3

Effects of Tolvaptan vs Fluid Restriction in Hospitalized Subjects With Dilutional Hyponatremia

NCT01227512

TERMINATED Phase 3

Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)

NCT01111552

TERMINATED Phase 3

Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)

NCT01111539

TERMINATED Phase 3

Safety and Tolerability of Aripiprazole in Adolescents With Schizophrenia or Children and Adolescents With Bipolar I Disorder, Manic or Mixed Episode With or Without Psychotic Features.

NCT01122927

COMPLETED Phase 3

An Open-Label, Multicenter, Rollover, Long-term Study of Aripiprazole Intramuscular Depot in Participants With Schizophrenia

NCT01129882

COMPLETED Phase 3

Tolvaptan Extension Study in Participants With ADPKD

NCT01214421

COMPLETED Phase 2

IV Busulfan Plus Bortezomib Conditioning Regimen for Second Autologous Stem Cell Transplant in Multiple Myeloma Patients

NCT01009840

COMPLETED Phase 2

Study of the Safety and Efficacy of OPC-34712 as a Complementary Therapy in the Treatment of Adult Attention Deficit/Hyperactivity Disorder

NCT01074294

COMPLETED Phase 2

Study of the Safety and Efficacy of OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder

NCT01052077

COMPLETED Phase 1

Phase 1, Open-label Trial to Determine Safety of OPB-51602 in Subjects With Advanced Cancer

NCT01423903

COMPLETED Phase 2

PK-directed Dose Adjustment of IV Busulfan Conditioning Regimen for Autologous Stem Cell Transplant in Lymphoma Patients

NCT00948090

COMPLETED Phase 2

Study of Safety & Tolerability of OPC-34712 as Adjunctive Therapy in Treatment of Adult Patients With Major Depressive Disorder

NCT01447576

COMPLETED Phase 2

Multicenter, Open-label, Safety and Tolerability Study

NCT01649557

COMPLETED Phase 2

Study to Evaluate the Efficacy, Safety, and Tolerability of Oral OPC-34712 and Aripiprazole for Treatment of Acute Schizophrenia

NCT00905307

COMPLETED Phase 2

Study of the Safety and Efficacy of OPC-34712 as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

NCT00797966

TERMINATED Phase 2

Pilot Study of Tetomilast in Chronic Obstructive Pulmonary Disease (COPD) Associated With Emphysema

NCT00874497

COMPLETED Phase 3

Intramuscular Depot Formulation of Aripiprazole as Maintenance Treatment in Patients With Schizophrenia

NCT00731549

COMPLETED Phase 3

Intramuscular Depot Formulation of Aripiprazole as Maintenance Treatment in Patients With Schizophrenia

NCT00706654

COMPLETED Phase 3

Intramuscular Depot Formulation of Aripiprazole as Maintenance Treatment in Patients With Schizophrenia

NCT00705783

COMPLETED Phase 2

A Trial to Evaluate OPC 67683 in Participants With Pulmonary Sputum Culture-positive, Multidrug-resistant Tuberculosis (TB)

NCT00685360

COMPLETED Phase 1

A Multiple Dose Safety, Tolerability and Pharmacokinetics Study in Adult Patients With Schizophrenia Following Administration of Aripiprazole IM Depot

NCT01870999

COMPLETED Phase 3

Effects of Titrated Oral Tolvaptan 15-60 mg Once Daily (QD) on Cognitive and Neurological Function in Elderly Hyponatremic Patients

NCT00550459

COMPLETED Phase 3

Tolvaptan Phase 3 Efficacy and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

NCT00428948

COMPLETED Phase 3

Study of Aripiprazole in the Treatment of Serious Behavioral Problems in Children and Adolescents With Autistic Disorder (AD)

NCT00365859

COMPLETED Phase 1

Aripiprazole and Effexor XR Drug Interaction Study

NCT00362271

COMPLETED Phase 1

Aripiprazole and Lexapro Drug Interaction Study

NCT00361790

COMPLETED Phase 1

Drug-drug Interaction Study of Aripiprazole and Lamotrigine in Patients With Bipolar Type I Disorder

NCT00321516

COMPLETED Phase 4

Aripiprazole Used as Dual Therapy in the Treatement of Patients With Chronic Stable Schizophrenia or Schizoaffective Disorder.

NCT00325689

COMPLETED Phase 3

Study of Aripiprazole in the Treatment of Children and Adolescents With Autistic Disorder (AD)

NCT00337571

COMPLETED Phase 3

Study of Aripiprazole in the Treatment of Children and Adolescents With Autistic Disorder (AD).

NCT00332241

COMPLETED Phase 4

A Phase IV Study of the Safety and Efficacy of Aripiprazole in Combination With Lamotrigine in the Long-Term Maintenance Treatment of Patients With Bipolar I Disorder With A Recent Manic or Mixed Episode

NCT00277212

COMPLETED Phase 2

Tolvaptan Open-label Pilot Efficacy, Tolerability, and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

NCT00413777

COMPLETED Phase 4

A Study of Aripiprazole (Abilify) in Patients With Bipolar Mania

NCT00261443

COMPLETED Phase 3

A Study of Aripiprazole in Patients With Major Depressive Disorder

NCT00105196

COMPLETED Phase 3

Aripiprazole in Children and Adolescents With Bipolar I Disorder

NCT00110461

COMPLETED Phase 2

Heart Pressure Assessment Study With Tolvaptan to Treat Congestive Heart Failure

NCT00132886

COMPLETED Phase 3

Study of Aripiprazole in Patients With Acute Bipolar Mania

NCT00097266

COMPLETED Phase 3

Study of Aripiprazole in Patients With Bipolar I Disorder

NCT00257972

COMPLETED Phase 3

A Long-Term Study of Aripiprazole in Patients With Major Depressive Disorder

NCT00095745

COMPLETED Phase 3

Aripiprazole Open-Label, Safety and Tolerability Study

NCT00102518

COMPLETED Phase 3

Aripiprazole in Adolescents With Schizophrenia

NCT00102063

COMPLETED Phase 3

A Study of Aripiprazole in Patients With Bipolar I Disorder With a Major Depressive Episode

NCT00094432

COMPLETED Phase 3

Aripiprazole in Patients With Acute Mania

NCT00095511

COMPLETED Phase 3

Study of Rebamipide Eye Drops to Treat Dry Eye

NCT00201955

COMPLETED Phase 3

A 1-Year Study in Multiple Clinics Testing Rebamipide Eye Drops for Dry Eye Compared With a Placebo

NCT00201981

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Phase Distribution

PhaseTrial count
Phase 1 52
Phase 2 45
Phase 3 109
Phase 4 10

What the Pipeline for Otsuka Pharmaceutical Development & Commercialization Shows

According to the ClinicalTrials.gov registry, Otsuka Pharmaceutical Development & Commercialization is linked to 221 US clinical trials across every stage of research activity. Of those, 8 studies are currently recruiting, about 4% of the sponsor's indexed portfolio, and 186 are already marked complete, representing roughly 84% of the total.

The phase mix for Otsuka Pharmaceutical Development & Commercialization reports 119 late-stage studies (Phase 3 and Phase 4 combined) and 97 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Otsuka Pharmaceutical Development & Commercialization is Schizophrenia with 12 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.