Ono Pharmaceutical Co.

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Ono Pharmaceutical Co. sits in the top decile of US sponsors by registered trial count (#842 of 15,742 sponsors by registered trial count).

17 total trials 5 currently recruiting 5 completed early-phase tilt top decile by trial count

Ono Pharmaceutical Co.: 17 sponsored US clinical trials, 5 recruiting.

Ono Pharmaceutical Co. sponsors 17 registered US clinical trials on ClinicalTrials.gov, 5 of them currently recruiting, and 5 completed. 3 of these trials are in Phase 3-4 (later-stage) and 14 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Primary CNS Lymphoma, with 1 trials.

Top-decile sponsor footprint

Ono Pharmaceutical Co. ranks in the top decile of sponsors by registered trial count (#842 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

17 total, page 1 of 1

RECRUITING Phase 3

INTREPID: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV)

NCT07429266

RECRUITING Phase 3

IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL)

NCT07104032

RECRUITING Phase 2

A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

NCT06948448

RECRUITING Phase 1

A Study to Investigate the Pharmacokinetics of Tirabrutinib in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Healthy Participants

NCT07198087

RECRUITING Phase 1

Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphoma

NCT05079282

ACTIVE NOT RECRUITING Phase 2

A Study of ONO-2020 in Participants With Mild to Moderate Alzheimer's Disease

NCT06881836

ACTIVE NOT RECRUITING Phase 2

A Phase 2 Study of ONO-2808 in Patients With Multiple System Atrophy

NCT05923866

ACTIVE NOT RECRUITING Phase 1

A Study to Investigate the Safety, Tolerability, PK, PD, and Efficacy of ONO-7018 in Patients With R/R NHL or CLL

NCT05515406

ACTIVE NOT RECRUITING Phase 2

Study of Tirabrutinib (ONO-4059) in Patients With Primary Central Nervous System Lymphoma (PROSPECT Study)

NCT04947319

COMPLETED Phase 1

A Phase 1 Study of ONO-2020 in Healthy Participants

NCT05507515

TERMINATED Phase 1

A Four-Part Study to Assess the Safety, Tolerability, PK and PD of ONO-5788 in Healthy Adult Volunteers

NCT03571594

TERMINATED Phase 1

Study of ONO-7579 in Patients With Advanced Solid Tumors/ NTRK Gene Fusion Positive Advanced Solid Tumors

NCT03182257

TERMINATED Phase 1

A Study of ONO-7475 in Patients With Acute Leukemias

NCT03176277

COMPLETED Phase 3

Study of Nivolumab in Unresectable Advanced or Recurrent Esophageal Cancer

NCT02569242

COMPLETED Phase 2

A 28 Day Study of ONO-9054 Ophthalmic Solution in Subjects With Ocular Hypertension (OHT) or Open-angle Glaucoma (OAG)

NCT02083289

COMPLETED Phase 1

ONO-7746 Study in Healthy Adult Subject

NCT01106664

COMPLETED Phase 1

ONO-7746 Study in Healthy Adult Subjects

NCT00956371

What is open in the Ono Pharmaceutical Co. pipeline

5 recruiting of 17 indexed (29% open); 5 completed (29%).

Phase mix: 3 late (III/IV) vs 14 early (I/II) (early-phase heavy).

Top condition: Primary CNS Lymphoma (1 trial), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Ono Pharmaceutical Co.: open-pipeline peers nationwide

Peers matched on 17 registered trials and 29% open enrollment, not the therapeutic-area sidebar.

Ono Pharmaceutical Co. sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 050100150 0%10%20%30%40% Total trials Recruiting share Ono Pharmaceutical Co.Achieve Life SciencesBioDelivery Sciences InternationalChugai PharmaceuticalConvaTecChildren's Hospital Los AngelesNatural Immune SystemsQueen's Medical CenterInova Health Care Services
Ono Pharmaceutical Co. sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Ono Pharmaceutical Co. sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 17 trials (± recruiting share)

Sponsors near 29% open enrollment (± trial volume)

What to do with this Ono Pharmaceutical Co. page

17 registered trials is a research-attention snapshot, not an endorsement of Ono Pharmaceutical Co. or any single study.

  • 5 of Ono Pharmaceutical Co.'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Primary CNS Lymphoma is the condition Ono Pharmaceutical Co. studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Primary CNS Lymphoma trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Ono Pharmaceutical Co. pipeline card: 17 registered trials from official public datasets.Report a data error.