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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Leukemia, Lymphocytic, Chronic, B-Cell: early-phase trial registry

5 of 12 indexed Leukemia, Lymphocytic, Chronic, B-Cell trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 5 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Leukemia, Lymphocytic, Chronic, B-Cell: 12 US clinical trials tracked, 5 recruiting.

Leukemia, Lymphocytic, Chronic, B-Cell is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Janssen Research & Development, running 3 of these trials.

Enrollment posture brief

Registry condition leukemia-lymphocytic-chronic-b-cell

OPEN 5 | RECR 42% | LATE 2 | EARLY 9 | RANK #1429 | SPON 3

Nearest open-share peer: Adiposity (42% recruiting · 12 trials)

Leukemia, Lymphocytic, C (th…42%Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Leukemia, Lymphocytic, Chronic, B-Cell

Leukemia, Lymphocytic, Chronic, B-Cell lists 5 open slots (42% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Leukemia, Lymphocytic, Chronic, B-Cell on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Leukemia, Lymphocytic, Chronic, B-Cell is recruiting below its size-band peers.

    5 of 12 indexed trials (41.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Leukemia, Lymphocytic, Chronic, B-Cell research.

    Janssen Research & Development accounts for 3 of 12 trials (25%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical Leukemia, Lymphocytic, Chronic, B-Cell enrolment sits around 211 participants.

    Median target enrolment is 211 among the 12 trials that report a genuine target (sentinel values excluded). 3 of those (25%) plan for fewer than 100 participants.

  4. Leukemia, Lymphocytic, Chronic, B-Cell research is mostly interventional.

    11 interventional and 1 observational studies make up this index (91.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 23Phase 32

Open and recent trials

12 total, page 1 of 1

RECRUITING 3,000 participants

Family Study of Lymphoproliferative Disorders

Mayo Clinic

NCT00626496

RECRUITING Phase 3 735 participants

A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).

Merck Sharp & Dohme

NCT05947851

RECRUITING Phase 1 320 participants

Study Evaluating Safety and Efficacy of JCAR017 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)

Juno Therapeutics, a Subsidiary of Celgene

NCT03331198

RECRUITING Phase 2 320 participants

A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia

Janssen Research & Development

NCT05963074

RECRUITING Phase 1 132 participants

Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Leukemias

National Cancer Institute (NCI)

NCT06364423

ACTIVE NOT RECRUITING Phase 1 316 participants

Study of Oral LOXO-338 in Patients With Advanced Blood Cancers

Eli Lilly and Company

NCT05024045

ACTIVE NOT RECRUITING Phase 3 211 participants

A Study of the Combination of Ibrutinib Plus Venetoclax Versus Chlorambucil Plus Obinutuzumab for the First-line Treatment of Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Janssen Research & Development

NCT03462719

ACTIVE NOT RECRUITING Phase 1 167 participants

A Study of JNJ-80948543, a T-cell Redirecting CD79b x CD20 x CD3 Trispecific Antibody, in Participants With Non-Hodgkin Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)

Janssen Research & Development

NCT05424822

ACTIVE NOT RECRUITING Phase 1 108 participants

A Study to Investigate the Safety, Tolerability, PK, PD, and Efficacy of ONO-7018 in Patients With R/R NHL or CLL

Ono Pharmaceutical Co.

NCT05515406

ACTIVE NOT RECRUITING Phase 2 50 participants

Zanubrutinib and Venetoclax as Initial Therapy for Chronic Lymphocytic Leukemia (CLL) With Response-based Obinutuzumab

Weill Medical College of Cornell University

NCT05650723

COMPLETED Phase 2 24 participants

Study to Evaluate Safety and Preliminary Efficacy of Tafasitamab With Idelalisib or Venetoclax in R/R CLL/SLL Patients Pretreated With BTKi

MorphoSys

NCT02639910

COMPLETED Phase 1 20 participants

Safety Study of CC-292 and Lenalidomide in Subjects With Chronic Lymphocytic Leukemia/ Small Lymphocytic Lymphoma

Celgene

NCT01732861

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 3
Phase 3 2

Named interventions

Most-linked intervention names on Leukemia, Lymphocytic, Chronic, B-Cell records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Venetoclax Drug
4 trials
Ibrutinib Drug
2 trials
CC-292 Drug
1 trials
Tafasitamab Biological
1 trials
JNJ-80948543 Drug
1 trials
ONO-7018 Drug
1 trials
Ibrutinib (as Subsequent Therapy) Drug
1 trials
Chlorambucil Drug
1 trials

US sites by state

Facility locations filed on Leukemia, Lymphocytic, Chronic, B-Cell trials. A trial with sites in several states counts in each.

California 6 trials
New York 5 trials
Florida 5 trials
Washington 4 trials
Minnesota 4 trials
Texas 3 trials
Tennessee 3 trials
Ohio 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Leukemia, Lymphocytic, Chronic, B-Cell page

12 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 5 Leukemia, Lymphocytic, Chronic, B-Cell trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Janssen Research & Development sponsors the most Leukemia, Lymphocytic, Chronic, B-Cell trials on record, review their full trial history before evaluating a specific study. See Janssen Research & Development's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Leukemia, Lymphocytic, Chronic, B-Cell condition card totals 12 registered trials; most-linked intervention Venetoclax; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.