National Cancer Institute (NCI)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Cancer Institute (NCI) sits in the top decile of US sponsors by registered trial count (#1 of 15,751 sponsors by registered trial count).

3,257 total trials 326 currently recruiting 2051 completed early-phase tilt top decile by trial count

National Cancer Institute (NCI): 3,257 sponsored US clinical trials, 326 recruiting.

National Cancer Institute (NCI) sponsors 3,257 registered US clinical trials on ClinicalTrials.gov, 326 of them currently recruiting, and 2,051 completed. 193 of these trials are in Phase 3-4 (later-stage) and 2,628 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Advanced Malignant Solid Neoplasm, with 67 trials.

Top-decile sponsor footprint

National Cancer Institute (NCI) ranks in the top decile of sponsors by registered trial count (#1 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

3,257 total, page 56 of 66

COMPLETED Phase 1

Imatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunction

NCT00025415

COMPLETED Phase 1

BMS-275291 in Treating Patients With HIV-Related Kaposi's Sarcoma

NCT00024024

TERMINATED NA

EF5 to Evaluate Tumor Hypoxia in Patients With High-Grade Soft Tissue Sarcoma or Mouth Cancer

NCT00896961

TERMINATED Phase 2

BMS-247550 in Treating Patients With Liver or Gallbladder Cancer

NCT00023946

COMPLETED Phase 2

R115777 to Treat Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas

NCT00021541

COMPLETED Phase 1

SU6668 in Treating Patients With Advanced Solid Tumors

NCT00024206

COMPLETED Phase 2

Interleukin-12 in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer

NCT00016289

COMPLETED Phase 1

BMS-214662 Plus Trastuzumab in Treating Patients With Advanced Solid Tumors

NCT00022529

COMPLETED Phase 2

Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic Osteosarcoma

NCT00023998

COMPLETED Phase 2

Gefitinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer

NCT00024089

COMPLETED Phase 1

Bevacizumab, Fluorouracil, and Hydroxyurea Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer

NCT00023959

COMPLETED Phase 2

Thalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

NCT00022581

COMPLETED Phase 2

PS-341 in Treating Patients With Metastatic Malignant Melanoma

NCT00024011

COMPLETED Phase 1

Hepatic Arterial Infusion With Melphalan in Treating Patients With Unresectable Liver Cancer

NCT00030082

COMPLETED

Long-Term Survival With HIV: Psychological and Behavioral Factors Associated With the Transition From Adolescence to Young Adulthood

NCT00026806

TERMINATED NA

Use of EF5 to Measure the Oxygen Level in Tumor Cells of Patients Undergoing Surgery or Biopsy for Newly Diagnosed Supratentorial Malignant Glioma

NCT00430079

TERMINATED Phase 2

Bevacizumab, Idarubicin, and Cytarabine in Treating Patients With Blast Phase Chronic Myelogenous Leukemia

NCT00023920

TERMINATED Phase 2

Interferon Alfa Plus Thalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

NCT00015912

COMPLETED Phase 2

Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma That Has Not Responded to Previous Treatment

NCT00022438

COMPLETED Phase 2

Ixabepilone in Treating Patients With Advanced Urinary Tract Cancer

NCT00021099

COMPLETED Phase 2

Combination Chemotherapy Plus Bevacizumab in Treating Patients With Metastatic Prostate Cancer

NCT00016107

COMPLETED Phase 2

Bortezomib in Treating Patients With Lymphoproliferative Disorders

NCT00023764

COMPLETED Phase 3

Combination Chemotherapy and Radiation Therapy With or Without Gefitinib in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery

NCT00020709

COMPLETED Phase 2

Combination Chemotherapy Followed By Donor Bone Marrow or Umbilical Cord Blood Transplant in Treating Children With Newly Diagnosed Juvenile Myelomonocytic Leukemia

NCT00025038

TERMINATED Phase 2

BMS-247550 in Treating Patients With Advanced Soft Tissue Sarcoma

NCT00022542

COMPLETED

Study of Plexiform Neurofibromas in Neurofibromatosis Type 1

NCT00006435

COMPLETED Phase 2

Bevacizumab to Treat Inflammatory Breast Cancer or Locally Advanced Breast Cancer

NCT00016549

COMPLETED Phase 2

Vaccine Therapy in Treating Patients With Metastatic Cancer

NCT00021164

COMPLETED Phase 1

STI571 Plus Cytarabine in Treating Patients With Chronic Myelogenous Leukemia

NCT00015834

COMPLETED Phase 1

Combination Chemotherapy in Treating Patients With Advanced Cancer

NCT00021073

COMPLETED Phase 1

EMD 121974 in Treating Patients With Advanced Solid Tumors

NCT00022113

COMPLETED Phase 2

CCI-779 in Treating Patients With Recurrent Glioblastoma Multiforme

NCT00016328

TERMINATED Phase 1

Bortezomib in Treating Patients With Recurrent Glioma

NCT00006773

TERMINATED Phase 3

Combination Chemotherapy, Surgery, and Radiation Therapy With or Without Dexrazoxane and Trastuzumab in Treating Women With Stage III or Stage IV Breast Cancer

NCT00016276

TERMINATED Phase 1

Imatinib Mesylate With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed or Recurrent Glioma

NCT00021229

COMPLETED

The Second Multicenter Hemophilia Cohort Study

NCT00341705

COMPLETED

Assessment of Blood Vessel Density in Kaposi's Sarcoma Lesions

NCT00026793

COMPLETED

Surveillance of Fungal Infections in Bone Marrow/Stem Cell and Organ Transplant Recipients

NCT00026767

COMPLETED Early Phase 1

Monoclonal Antibody Therapy and Peripheral Stem Cell Transplant in Treating Patients With Non-Hodgkin's Lymphoma

NCT00017381

COMPLETED Phase 1

Flavopiridol in Treating Children With Relapsed or Refractory Solid Tumors or Lymphomas

NCT00012181

COMPLETED Phase 1

Monoclonal Antibody Therapy in Treating Patients With Chronic Lymphocytic Leukemia, Lymphocytic Lymphoma, Acute Lymphoblastic Leukemia, or Acute Myeloid Leukemia

NCT00017472

COMPLETED Phase 2

S0108 Bevacizumab in Treating Patients With Non-Hodgkin's Lymphoma

NCT00016094

COMPLETED NA

Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

NCT00016302

COMPLETED Phase 2

Thalidomide in Treating Patients With Myelodysplastic Syndrome

NCT00015990

COMPLETED Phase 2

Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer Previously Treated With Irinotecan

NCT00016978

COMPLETED Phase 1

Combination Chemotherapy Plus Oblimersen in Treating Patients With Previously Untreated Extensive-Stage Small Cell Lung Cancer

NCT00017251

TERMINATED Phase 1

Radiolabeled Monoclonal Antibody Plus Rituximab With and Without Filgrastim and Interleukin-11 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

NCT00012298

COMPLETED Early Phase 1

Pilot Study of Non-Myeloablative, HLA-Matched Allogeneic Stem Cell Transplantation for Pediatric Hematopoietic Malignancies

NCT00013533

COMPLETED Phase 2

Depsipeptide to Treat Patients With Cutaneous T-Cell Lymphoma and Peripheral T-Cell Lymphoma

NCT00007345

COMPLETED Phase 1

Chemotherapy Plus Sargramostim in Treating Patients With Refractory Myeloid Cancer

NCT00012376

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What is open in the National Cancer Institute (NCI) pipeline

326 recruiting of 3,257 indexed (10% open); 2,051 completed (63%).

Phase mix: 193 late (III/IV) vs 2,628 early (I/II) (early-phase heavy).

Top condition: Advanced Malignant Solid Neoplasm (67 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.