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NCT00023920 · ClinicalTrials.gov registry record · Phase 2

Bevacizumab, Idarubicin, and Cytarabine in Treating Patients With Blast Phase Chronic Myelogenous Leukemia

A Phase 2 study, sponsored by National Cancer Institute (NCI).

Terminated
Registry status
Phase 2
Development phase
60
Enrollment target

NCT00023920: Clinical Trial Phase 2 study, sponsored by National Cancer Institute (NCI).

NCT00023920 is a Phase 2 study that was terminated before completion, run by National Cancer Institute (NCI). The registered enrollment target is 60 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00023920, a Phase 2 study, was terminated before completion, sponsored by National Cancer Institute (NCI).

TERMINATED
Registry status
Phase 2
Development phase
60 participants
Enrollment target

Study Summary

This phase II trial is to see if combining bevacizumab with idarubicin and cytarabine works better in treating patients who have blast phase chronic myelogenous leukemia. Monoclonal antibodies, such as bevacizumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or deliver cancer-killing substances to them. Drugs used in chemotherapy, such as idarubicin and cytarabine, work in different ways to stop cancer cells from dividing so they stop growing or die. Combining monoclonal antibody therapy with chemotherapy may be an effective treatment for blast phase chronic myelogenous leukemia

Interventions

  • BIOLOGICAL bevacizumab
  • DRUG cytarabine
  • DRUG idarubicin

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2001-07
Phase Phase 2
National Cancer Institute (NCI)

3,257 total trials

Why NCT00023920 stopped before completion

NCT00023920 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower).

The record links to 0 conditions, and to 3 interventions - of which bevacizumab is the first listed.

NCT00023920 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00023920 about?

NCT00023920 is a clinical study titled "Bevacizumab, Idarubicin, and Cytarabine in Treating Patients With Blast Phase Chronic Myelogenous Leukemia". This phase II trial is to see if combining bevacizumab with idarubicin and cytarabine works better in treating patients who have blast phase chronic myelogenous leukemia. Monoclonal antibodies, such as bevacizumab, can block cancer growth in different ways. Some block the ability of cancer cells to ...

What is the current status of trial NCT00023920?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2001-07.

What interventions are being tested in trial NCT00023920?

The interventions under investigation include: bevacizumab (BIOLOGICAL), cytarabine (DRUG), idarubicin (DRUG).

Who is sponsoring clinical trial NCT00023920?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00023920's enrollment target sits among peer trials

60 1027th of 2000 higher than 868 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00023920, the US trial registry maintained by the National Library of Medicine. NCT00023920 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.