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NCT00026793 · ClinicalTrials.gov registry record
Assessment of Blood Vessel Density in Kaposi's Sarcoma Lesions
A clinical trial, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- 29
- Enrollment target
NCT00026793: Completed study, sponsored by National Cancer Institute (NCI).
NCT00026793 is a clinical trial that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 29 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00026793 has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- 29 participants
- Enrollment target
Study Summary
The purpose of this study is to develop imaging techniques to determine the density of blood vessels and the amount of blood flow in Kaposi s sarcoma (KS) tumors. KS tumors depend on the formation of new blood vessels for their growth. Some experimental therapies for KS are directed at reducing the amount of blood vessels and blood flow in these lesions. Measurement of blood vessel density and blood flow in these lesions could be useful in evaluating the effectiveness of both standard and experimental treatments for this disease. Patients 18 years of age or older with Kaposi's sarcoma involving the skin may be eligible for this study. Participants will have photographs taken of their lesions and will undergo three imaging procedures (described below) at the beginning of the study (baseline) and then about once every 3 months or so while on the study (up to 2 years) to compare the test results over time. (Imaging may be done at more or less frequent intervals depending on the findings.) A small amount of blood (less than a tablespoon) will be drawn the day of each imaging procedure. Laser Doppler imaging This technique measures the amount of blood flow in KS lesions by scanning the lesions with a low-power laser beam. Each lesion takes about 3 minutes to scan. The imaging may be done before and after a blood pressure cuff around the arm is inflated for a short time (usually less than 30 seconds). Multi-spectral imaging This technique uses light to measure the total blood volume in each lesion and how much oxygen is in the blood. Oxygen is carried to the body s cells by a protein in red blood cells called hemoglobin. The light on the multi-spectral imaging instrument is absorbed differently depending on whether the hemoglobin has oxygen attached to it or not. It takes about 2 minutes to scan each lesion. Infrared thermal imaging This test uses a special camera to take digital infrared pictures of the skin. Images formed of the temperature of the KS lesions are use
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2001-04-23 |
| Est. Completion | 2017-12-20 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00026793
The ClinicalTrials.gov registry entry for NCT00026793 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 29 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT00026793 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00026793 about?
NCT00026793 is a clinical study titled "Assessment of Blood Vessel Density in Kaposi's Sarcoma Lesions". The purpose of this study is to develop imaging techniques to determine the density of blood vessels and the amount of blood flow in Kaposi s sarcoma (KS) tumors. KS tumors depend on the formation of new blood vessels for their growth. Some experimental therapies for KS are directed at reducing the ...
What is the current status of trial NCT00026793?
This trial is currently completed. The enrollment target is 29 participants. The study started on 2001-04-23. Estimated completion is 2017-12-20.
Who is sponsoring clinical trial NCT00026793?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
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