National Cancer Institute (NCI)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Cancer Institute (NCI) sits in the top decile of US sponsors by registered trial count (#1 of 15,751 sponsors by registered trial count).

3,257 total trials 326 currently recruiting 2051 completed early-phase tilt top decile by trial count

National Cancer Institute (NCI): 3,257 sponsored US clinical trials, 326 recruiting.

National Cancer Institute (NCI) sponsors 3,257 registered US clinical trials on ClinicalTrials.gov, 326 of them currently recruiting, and 2,051 completed. 193 of these trials are in Phase 3-4 (later-stage) and 2,628 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Advanced Malignant Solid Neoplasm, with 67 trials.

Top-decile sponsor footprint

National Cancer Institute (NCI) ranks in the top decile of sponsors by registered trial count (#1 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

3,257 total, page 46 of 66

TERMINATED Phase 3

Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer

NCT00096265

COMPLETED Phase 1

XK469R in Treating Patients With Refractory Hematologic Cancer

NCT00095797

COMPLETED Phase 2

Sorafenib Tosylate in Treating Patients With Malignant Mesothelioma.

NCT00107432

COMPLETED Phase 1

Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors

NCT00095940

COMPLETED Phase 2

Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatment

NCT00091182

COMPLETED Phase 2

Romidepsin in Treating Patients With Recurrent and/or Metastatic Thyroid Cancer That Has Not Responded to Radioactive Iodine

NCT00098813

COMPLETED Phase 2

Fludarabine, Rituximab, and Alemtuzumab in Treating Patients With Chronic Lymphocytic Leukemia

NCT00098670

COMPLETED Phase 1

CCI-779 and EKB-569 in Treating Patients With Advanced Solid Tumors

NCT00098501

COMPLETED Phase 2

S0420, Sorafenib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

NCT00096512

COMPLETED Phase 1

Sorafenib in Treating Patients With Metastatic or Unresectable Solid Tumors, Multiple Myeloma, or Non-Hodgkin's Lymphoma With or Without Impaired Liver or Kidney Function

NCT00118170

COMPLETED Phase 1

MS-275 and Isotretinoin in Treating Patients With Metastatic or Advanced Solid Tumors or Lymphomas

NCT00098891

COMPLETED Phase 1

Tipifarnib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT00101296

COMPLETED Phase 2

Sorafenib in Treating Patients With Persistent or Recurrent Ovarian Epithelial or Peritoneal Cancer

NCT00093626

COMPLETED Phase 2

Lapatinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer

NCT00098631

COMPLETED Phase 2

Lapatinib in Treating Brain Metastases in Patients With Stage IV Breast Cancer and Brain Metastases

NCT00098605

COMPLETED Phase 1

Doxorubicin Hydrochloride and Alvocidib in Treating Patients With Metastatic or Recurrent Sarcoma That Cannot Be Removed By Surgery

NCT00098579

TERMINATED Phase 2

Sorafenib Tosylate in Treating Patients With Locally Advanced, Metastatic, or Locally Recurrent Thyroid Cancer

NCT00095693

TERMINATED Phase 2

3-AP and Gemcitabine in Treating Patients With Refractory Metastatic Breast Cancer

NCT00095888

TERMINATED Phase 2

FR901228 in Treating Patients With Refractory Stomach Cancer or Gastroesophageal Junction Cancer

NCT00098527

TERMINATED Phase 1

Flavopiridol in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Chronic Myelogenous Leukemia

NCT00101231

TERMINATED Phase 2

Sorafenib and Interferon Alfa in Treating Patients With Locally Advanced or Metastatic Kidney Cancer

NCT00098618

TERMINATED Phase 2

Idarubicin and Cytarabine With or Without Bevacizumab in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT00096148

COMPLETED Phase 2

Exercise in Women at Risk for Breast Cancer

NCT00092950

COMPLETED Phase 3

Fluorouracil, Leucovorin, and Oxaliplatin With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II or Stage III Colon Cancer

NCT00096278

TERMINATED Phase 2

Vaccine Treatment of Kidney Cancer

NCT00089778

COMPLETED

Childhood Cancer and Plexiform Neurofibroma Tissue Microarray for Molecular Target Screening and Clinical Drug Development

NCT00340522

COMPLETED

Retrospective Analysis of a Drug-Metabolizing Genotype in Cancer Patients and Correlation With Pharmacokinetic and Pharmacodynamics Data

NCT00341939

COMPLETED Phase 2

A Phase II Study of BAY 43-9006 (Sorafenib) in Metastatic, Androgen-Independent Prostate Cancer

NCT00090545

COMPLETED NA

Erlotinib in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer

NCT00085280

COMPLETED Phase 1

UMCC 2003-064 Resveratrol in Preventing Cancer in Healthy Participants

NCT00098969

COMPLETED Phase 2

S0341: Erlotinib in Treating Patients With Advanced Primary Non-Small Cell Lung Cancer

NCT00087412

COMPLETED Phase 2

Ixabepilone in Treating Patients With Metastatic Prostate Cancer

NCT00087139

COMPLETED Phase 1

Bortezomib, Paclitaxel, Carboplatin and Radiation Therapy for Non-Small Cell Lung Cancer

NCT00093756

COMPLETED Phase 2

Sorafenib and Interferon Alfa in Treating Patients With Metastatic or Unresectable Kidney Cancer

NCT00101114

COMPLETED Phase 1

Idarubicin, Cytarabine, and Tipifarnib in Treating Patients With Newly Diagnosed Myelodysplastic Syndromes or Acute Myeloid Leukemia

NCT00096122

COMPLETED Phase 2

Sorafenib and Gemcitabine in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

NCT00095966

COMPLETED Phase 2

S0432 Tipifarnib in Treating Older Patients With Acute Myeloid Leukemia

NCT00093418

COMPLETED Phase 1

Tanespimycin in Treating Young Patients With Recurrent or Refractory Leukemia or Solid Tumors

NCT00093821

COMPLETED Phase 2

SGN-00101 Vaccine in Treating Human Papillomavirus in Patients Who Have Abnormal Cervical Cells

NCT00091130

COMPLETED Phase 2

Sorafenib in Treating Patients With Metastatic Breast Cancer

NCT00096434

TERMINATED Phase 2

Depsipeptide (Romidepsin) in Treating Patients With Recurrent Ovarian Epithelial or Peritoneal Cavity Cancer

NCT00091195

TERMINATED Phase 1

Decitabine in Treating Patients With Advanced Refractory Solid Tumors or Lymphomas

NCT00089089

TERMINATED Phase 1

Cultured White Cells Plus Interleukin-2 to Treat Advanced Kidney Cancer

NCT00091611

COMPLETED Phase 3

Tipifarnib in Treating Patients With Acute Myeloid Leukemia in Remission

NCT00093470

COMPLETED NA

Vaccine Therapy, Chemotherapy, and Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed With Surgery

NCT00091039

COMPLETED Phase 1

Interleukin-7 and Vaccine Therapy in Treating Patients With Metastatic Melanoma

NCT00091338

COMPLETED Phase 2

Apolizumab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

NCT00089154

COMPLETED Phase 2

Sorafenib With or Without Paclitaxel and Carboplatin in Treating Patients With Recurrent Ovarian Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer

NCT00096200

TERMINATED Phase 3

Phase III Trial Of Docetaxel Versus Docetaxel Plus ZD1839 In Head And Neck Cancer

NCT00088907

COMPLETED

Genetic Analysis of Psoriasis and Psoriatic Arthritis

NCT00341809

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What is open in the National Cancer Institute (NCI) pipeline

326 recruiting of 3,257 indexed (10% open); 2,051 completed (63%).

Phase mix: 193 late (III/IV) vs 2,628 early (I/II) (early-phase heavy).

Top condition: Advanced Malignant Solid Neoplasm (67 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.