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NCT00101231 · ClinicalTrials.gov registry record · Phase 1

Flavopiridol in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Chronic Myelogenous Leukemia

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Terminated
Registry status
Phase 1
Development phase
88
Enrollment target

NCT00101231: Clinical Trial Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT00101231 is a Phase 1 study that was terminated before completion, run by National Cancer Institute (NCI). The registered enrollment target is 88 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (47% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00101231, a Phase 1 study, was terminated before completion, sponsored by National Cancer Institute (NCI).

TERMINATED
Registry status
Phase 1
Development phase
88 participants
Enrollment target

Study Summary

This phase I trial is studying the side effects and best dose of flavopiridol in treating patients with relapsed or refractory acute myeloid leukemia, acute lymphoblastic leukemia, or chronic myelogenous leukemia. Drugs used in chemotherapy, such as flavopiridol, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.

Interventions

  • DRUG alvocidib

Trial Details

FieldValue
Enrollment Target 88 participants
Start Date 2004-10
Phase Phase 1
National Cancer Institute (NCI)

3,257 total trials

Why NCT00101231 stopped before completion

NCT00101231 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 88 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (47% higher).

The record links to 0 conditions, and to 1 intervention - of which alvocidib is the first listed.

NCT00101231 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00101231 about?

NCT00101231 is a clinical study titled "Flavopiridol in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Chronic Myelogenous Leukemia". This phase I trial is studying the side effects and best dose of flavopiridol in treating patients with relapsed or refractory acute myeloid leukemia, acute lymphoblastic leukemia, or chronic myelogenous leukemia. Drugs used in chemotherapy, such as flavopiridol, work in different ways to stop the g...

What is the current status of trial NCT00101231?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 88 participants. The study started on 2004-10.

What interventions are being tested in trial NCT00101231?

The interventions under investigation include: alvocidib (DRUG).

Who is sponsoring clinical trial NCT00101231?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00101231's enrollment target sits among peer trials

88 650th of 2000 higher than 1,350 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00101231, the US trial registry maintained by the National Library of Medicine. NCT00101231 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.