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NCT00096200 · ClinicalTrials.gov registry record · Phase 2

Sorafenib With or Without Paclitaxel and Carboplatin in Treating Patients With Recurrent Ovarian Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer

A Phase 2 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
44
Enrollment target

NCT00096200: Completed Phase 2 study, sponsored by National Cancer Institute (NCI).

NCT00096200 is a Phase 2 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 44 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00096200, a Phase 2 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
44 participants
Enrollment target

Study Summary

Sorafenib may stop the growth of tumor cells by blocking the enzymes necessary for their growth and by stopping blood flow to the tumor. Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop tumor cells from dividing so they stop growing or die. Giving sorafenib together with chemotherapy may kill more tumor cells. This randomized phase II trial is studying how well giving sorafenib together with paclitaxel and carboplatin works in treating patients with recurrent ovarian cancer, primary peritoneal cancer, or fallopian tube cancer. (Sorafenib only group closed as of 10/10/2008).

Primary Outcome

Patients should be reevaluated for response every 2 cycles (6 weeks). Patients who continue on Arm A of treatment for more than 12 months should be reevaluated for response every 3 cycles (9 weeks). In addition to a baseline scan, confirmatory scans should also be obtained 4 weeks following initial documentation of objective response.

Interventions

  • DRUG Carboplatin
  • DRUG Paclitaxel
  • DRUG Sorafenib Tosylate

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2004-08
Est. Completion 2011-08
Phase Phase 2
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00096200 record still lists

NCT00096200 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (67% lower).

The record links to 0 conditions, and to 3 interventions - of which Carboplatin is the first listed.

NCT00096200 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00096200 about?

NCT00096200 is a clinical study titled "Sorafenib With or Without Paclitaxel and Carboplatin in Treating Patients With Recurrent Ovarian Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer". Sorafenib may stop the growth of tumor cells by blocking the enzymes necessary for their growth and by stopping blood flow to the tumor. Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop tumor cells from dividing so they stop growing or die. Giving sorafe...

What is the current status of trial NCT00096200?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 2004-08. Estimated completion is 2011-08.

What interventions are being tested in trial NCT00096200?

The interventions under investigation include: Carboplatin (DRUG), Paclitaxel (DRUG), Sorafenib Tosylate (DRUG).

Who is sponsoring clinical trial NCT00096200?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00096200's enrollment target sits among peer trials

44 1322nd of 2000 higher than 669 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00096200, the US trial registry maintained by the National Library of Medicine. NCT00096200 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.