Mayo Clinic
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,742 sponsors by registered trial count).
Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.
Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.
Top-decile sponsor footprint
Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,816 of 2,102 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
2,844 total, page 12 of 57
Graded Exercise Hypoxia Testing
NCT06901284
Transcranial Direct Current Stimulation (tDCS) as an Adjunctive Treatment for Treatment Resistant Depression (TRD)
NCT06236711
Dialysis Catheter Caps Case Feasibility Study
NCT06905080
Electromagnetic Transduction Therapy on Osteoarthritis in the Foot and Ankle
NCT06696118
Mixed-Methods Evaluation of Short-, Medium-, and Long-Term Outcomes Following Hip Treatment
NCT06891196
Sotatercept on Central Cardiopulmonary Performance and Peripheral Oxygen Transport During Exercise in Pulmonary Arterial Hypertension
NCT06409026
Metal Ion Concentrations After Total Knee Arthroplasty
NCT06447922
A Study of Artificial Intelligence ECG With ECG Devices to Detect Hypertrophic Cardiomyopathy Distinct From Athlete's
NCT06290570
Dual Implant Versus Single Implant Distal End of Femur
NCT06032299
A Study of Melatonin Concentration During Lactation
NCT06393296
Realtime Diagnosis From Electrocardiogram Artificial Intelligence-Guided Screening for Atrial Fibrillation With Long Follow-Up (REGAL)
NCT05923359
A Study of Hydrogen Peroxide-Generating E-bandage Safety
NCT05940207
Remote Home-Based Exercise Program for Strength Training in Endometrial Cancer Survivors in Rural Areas
NCT06213571
Dry Needling and Therapeutic Exercise on Sleep in Individuals With Chronic Neck Pain and Sleep Disturbance
NCT06275074
Implementation of a Digital Clinic for Alcohol-associated Liver Disease and Alcohol Use Disorder (DALC)
NCT06319222
Optimizing the Patient Experience Through Provider Coaching or Communication Intervention
NCT06329557
Smartphones Aggravating Anxiety Symptoms
NCT06361342
CJNJ-67652000 and Prednisone for Treatment of Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations
NCT05689021
LLLT to Reduce Low Back Pain
NCT06007976
Metyrapone for Mild Autonomous Cortisol Secretion (MACS)
NCT06106295
Vitamin D Sulfates in Breastmilk
NCT06203041
Three-Axis Wearable Adaptive Vestibular Stimulator
NCT06106256
A Study of Adipose Tissue in Adaptive Responses to Exercise
NCT06053125
Allogeneic BM-MSC's in Patients With Lumbar Facet Arthropathy
NCT06001853
Optimal Stent Duration After Ureteroscopy
NCT06045962
Evaluation of the Impact of Empty Versus Full Bladder in Patients With Prostate Cancer, RELIEF Trial
NCT06037863
Daily Adaptive Post-Prostatectomy With Stereotactic Ablative Radiotherapy in Patients With Prostate Cancer
NCT05830838
Role of ROS and cAMP-PKA Biomarkers in ADPKD
NCT07217158
A Study of Ado-trastuzumab Emtansine (T-DM1)-Induced Peripheral Neuropathy in HER2-positive Breast Cancer Patients
NCT05889988
Glucagon Suppression by Hyperglycemia in the Presence and Absence of Amino Acid Infusion
NCT05264727
TTI-622 in Combination With Pembrolizumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma
NCT05507541
Short Course Radiotherapy for the Treatment of Patients With Glioblastoma, SAGA Study
NCT05781321
A Study of Time Restricted Eating in Obese Adults
NCT05660291
A Study of Caregiver Connections Via Technology in Dementia
NCT05779839
A Study of Cardiovascular Disparities in the Greater Mankato Somali Community to Prevent Hypertension
NCT05873153
Pirtobrutinib and Venetoclax With MRD Detection for Previously Untreated Chronic Lymphocytic Leukemia
NCT05677919
Long Term Followup of Patients Enrolled in MC1137, BEAUTY Study
NCT05703399
Statins for the Treatment of NASH
NCT04679376
Combination Treatment Therapy Approaches for the Treatment of High-Risk Multiple Myeloma, REACH Trial
NCT05497804
Comparing Perioperative Education Modalities for ACL Reconstruction on Patient Satisfaction, Self-Efficacy, and Surgical Outcomes
NCT05273463
Iberdomide, Daratumumab, Bortezomib, and Dexamethasone for Treatment of Newly Diagnosed Multiple Myeloma, IDEAL Study
NCT05392946
Florida Cerebrovascular Disease Biorepository and Genomics Center
NCT05491980
ALSENLITE: Senolytics for Alzheimer's Disease
NCT04785300
CREST-2 Long-term Observational Extension Study
NCT05465122
Genetically Engineered Cells (MUC1-Activated T-Cells) for the Treatment of MUC1 Positive Recurrent or Refractory Multiple Myeloma
NCT05411497
A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer
NCT05232851
Reducing Opioid Prescription After Kidney Stone Removal Surgery
NCT05353478
SoftHand Comparison Study
NCT05328934
Pro-active Genetic Testing in Kidney Transplant Patients
NCT05298904
Cancer Survivor Cardiomyopathy Detection
NCT05201014
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 435 |
| Phase 2 | 386 |
| Phase 3 | 86 |
| Phase 4 | 166 |
Therapeutic Areas
What is open in the Mayo Clinic pipeline
544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).
Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).
Top condition: Healthy (36 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Mayo Clinic: open-pipeline peers nationwide
Peers matched on 2,844 registered trials and 19% open enrollment, not the therapeutic-area sidebar.
Mayo Clinic sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 2,844 trials (± recruiting share)
- M.D. Anderson Cancer Center · 2,692 trials · 20% recruiting
- National Cancer Institute (NCI) · 3,257 trials · 10% recruiting
- Massachusetts General Hospital · 2,032 trials · 17% recruiting
- National Institute of Allergy and Infectious Diseases (NIAID) · 2,006 trials · 8% recruiting
Sponsors near 19% open enrollment (± trial volume)
- University of South Carolina · 19% recruiting · 157 trials
- Vanderbilt University Medical Center · 19% recruiting · 677 trials
- MemorialCare Health System · 19% recruiting · 21 trials
- University of North Texas Health Science Center · 19% recruiting · 21 trials
Related
What to do with this Mayo Clinic page
2,844 registered trials is a research-attention snapshot, not an endorsement of Mayo Clinic or any single study.
- 544 of Mayo Clinic's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Healthy is the condition Mayo Clinic studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Mayo Clinic pipeline card: 2,844 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.