Massachusetts General Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).

2,032 total trials 336 currently recruiting 1284 completed early-phase tilt top decile by trial count

Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.

Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.

Top-decile sponsor footprint

Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,032 total, page 38 of 41

COMPLETED

Hormone Dynamics and Bone Mineral Density in Anorexia Nervosa v. Hypothalamic Amenorrhea

NCT00556036

COMPLETED Phase 2

Study of SU11248 in Men With Advanced Prostate Cancer

NCT00299741

COMPLETED Phase 4

Improving Treatment Outcomes in Pharmacotherapy of Generalized Social Anxiety Disorder

NCT00282828

TERMINATED Phase 3

Escitalopram in Treating Depression in Patients With Advanced Lung or Gastrointestinal Cancer

NCT00387348

COMPLETED NA

The Treatment of Insomnia in Symptomatic Peri- and Postmenopausal Women

NCT00374192

COMPLETED Phase 4

A Placebo-Controlled Single-Dose Trial of Sildenafil in Schizophrenia

NCT00455715

COMPLETED Phase 2

Assessment of the Antiviral Effect of Atorvastatin on Hepatitis C Virus

NCT00403533

TERMINATED Phase 4

Ziprasidone for the Treatment of Generalized Anxiety in Patients With Bipolar Disorder

NCT00374543

COMPLETED Phase 4

A Study of Repeat Dosing of OROS® Methylphenidate Hydrochloride (CONCERTA®) and Immediate Release Methylphenidate Hydrochloride in Healthy Adults

NCT00302458

COMPLETED Phase 2

Effect of Growth Hormone on Bone Metabolism in Anorexia Nervosa

NCT00283595

COMPLETED

CMC Arthritis - Neoprene Vs. Thermoplast Short Opponens Splinting

NCT00438763

COMPLETED

A Clinical Trial of Splinting for DeQuervain's Tenosynovitis

NCT00438191

COMPLETED Phase 4

Duloxetine for the Treatment of Obsessive Compulsive Disorder (OCD)

NCT00464698

TERMINATED Phase 4

Extended Duration Nicotine Replacement Therapy and Bupropion in Smokers With Schizophrenia

NCT01576640

TERMINATED NA

Effectiveness of a Computer Application in Improving Pulmonary Artery Catheter Waveform Interpretation

NCT00138073

TERMINATED Phase 4

Fluoxetine for Obsessive-Compulsive Disorder in Children and Adolescents With Bipolar Disorder

NCT00592852

COMPLETED Phase 4

Understanding Experimentally Induced Hot Flushes

NCT00455689

COMPLETED Phase 4

Memantine and Cognitive Dysfunction in Bipolar Disorder

NCT00586066

COMPLETED NA

The Development and Evaluation of an "E-Visit" Program for the Management of Acne

NCT00417456

COMPLETED Phase 2

Effectiveness of Behavior Therapy and Psychosocial Therapy for the Treatment of Tourette Syndrome and Chronic Tic Disorder

NCT00231985

COMPLETED Phase 2

Gefitinib in Treating Patients With Previously Untreated Stage IIIB or Stage IV Non-Small Cell Lung Cancer

NCT00411047

COMPLETED NA

Use of NT-proBNP Testing to Guide Heart Failure Therapy in the Outpatient Setting.

NCT00351390

COMPLETED Phase 2

Study of the Effects of Risperdal Consta on Brain Reward Circuitry Function, Craving and Cocaine Use in Active Cocaine Dependence

NCT00385801

COMPLETED NA

EEG Studies of Induction and Recovery From Propofol Induced General Anesthesia

NCT01543633

COMPLETED

Bipolar Disorder in Pregnancy and the Postpartum Period: Predictors of Morbidity

NCT00580268

COMPLETED Phase 2

Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus

NCT00133367

COMPLETED

Risk Factors for Barrett's Esophagus in Patients With BE, Gastroesophageal Reflux, or Gastrointestinal Bleeding

NCT00445653

COMPLETED NA

Pharmacokinetics of Curcumin in Healthy Volunteers

NCT00181662

COMPLETED Phase 4

Equetro for the Treatment of Mania in Children Ages 6-12 With Bipolar Disorder

NCT00181870

COMPLETED NA

Calcium Supplementation for a Healthy Weight (CaSHeW)

NCT01363115

COMPLETED Phase 3

Comparison of Lantus and Neutral Protamine Hagedorn (NPH) Insulin in the Dawn Phenomenon

NCT00694122

COMPLETED Phase 4

Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder

NCT00120250

COMPLETED

Splinting for Dupuytren's Contracture Release

NCT00575458

COMPLETED Phase 2

Evaluation of Computer-assisted, Non-cathartic CT Colonography

NCT01200303

TERMINATED Phase 3

SSRI Administration to Reduce Acute Stress Disorder Symptoms and Prevent Depression and PTSD in Physical Trauma Victims

NCT00114374

TERMINATED Phase 1

Study of Velcade and Thalidomide in Patients With Myelodysplasia

NCT00271804

TERMINATED

Study to Identify Markers of Insulin Resistance During Growth Hormone Treatment for Short Stature

NCT00121875

COMPLETED

Rule Out Myocardial Infarction by Computer Assisted Tomography

NCT00990262

COMPLETED

Family Risk Analysis of Substance Use in Attention Deficit Hyperactivity Disorder (ADHD) Youth Treated With Concerta

NCT00181792

COMPLETED

Neuroendocrine Modulation of Metabolic Effects in Overweight Adolescents

NCT00140842

COMPLETED Phase 3

Effectiveness of Escitalopram in the Treatment of Body Dysmorphic Disorder

NCT00149799

COMPLETED NA

Effectiveness of Acupuncture for Depressed Patients Not Taking Antidepressant Medications

NCT01634022

COMPLETED Phase 4

Aripiprazole for the Treatment of Refractory Anxiety

NCT00438386

COMPLETED Phase 2

Creatine Safety & Tolerability in Huntington's Disease

NCT01412151

TERMINATED Phase 3

Imuran (Azathioprine) Dose-Ranging Study in Crohn's Disease

NCT00098111

COMPLETED NA

Improving Pediatric Safety and Quality With Health Care Information Technology

NCT00134823

COMPLETED Phase 3

A PET Study Examining Pharmacokinetics and Dopamine Transporter Receptor Occupancy Of Two Long-Acting Formulations of Methylphenidate in Adults

NCT00301639

COMPLETED Phase 4

Effectiveness of Aripiprazole for Improving Side Effects of Clozapine in the Treatment of People With Schizophrenia

NCT00345033

TERMINATED Phase 4

Pilot Study of Bupropion for Smoking Cessation in Postpartum Non-breastfeeding Women

NCT00119210

COMPLETED NA

An Intervention to Address Parental Smoking During the Postpartum Hospitalization.

NCT00844818

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Phase Distribution

PhaseTrial count
Phase 1 226
Phase 2 289
Phase 3 58
Phase 4 182

What is open in the Massachusetts General Hospital pipeline

336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).

Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).

Top condition: Depression (29 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.