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NCT01543633 · ClinicalTrials.gov registry record · NA
EEG Studies of Induction and Recovery From Propofol Induced General Anesthesia
A NA study of Brain Activity Under Sedation, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- NA
- Development phase
- 36
- Enrollment target
- 1
- Study location
NCT01543633: Completed NA study of Brain Activity Under Sedation, sponsored by Massachusetts General Hospital.
NCT01543633 is a NA study of Brain Activity Under Sedation that has completed, run by Massachusetts General Hospital. The registered enrollment target is 36 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01543633, a NA study of Brain Activity Under Sedation, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 36 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to investigate how the commonly used anesthetic drug propofol works in the brain to produce loss of consciousness. While under general anesthesia your brain waves will be measured using electroencephalogram (EEG). On a separate day, the patient's brain will be imaged using magnetic resonance imaging (MRI).
Primary Outcome
We used EEG measurements to study the dynamics of loss of consciousness, auditory processing, sensation, and memory under general anesthesia induced with propofol. The EEG data in each of the three specific aims will be analyzed using spectral methods, source localization, and event-related potentials. Through spectral analysis, EEG power (in decibels) in alpha, slow, and delta bands are measured.
Conditions Studied
Interventions
- DRUG Propofol
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2005-08 |
| Est. Completion | 2020-07 |
| Phase | NA |
What the finished NCT01543633 record still lists
NCT01543633 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Brain Activity Under Sedation appearing as the primary indexed condition, and to 1 intervention - of which Propofol is the first listed.
NCT01543633 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT01543633 about?
NCT01543633 is a clinical study titled "EEG Studies of Induction and Recovery From Propofol Induced General Anesthesia". The purpose of this study is to investigate how the commonly used anesthetic drug propofol works in the brain to produce loss of consciousness. While under general anesthesia your brain waves will be measured using electroencephalogram (EEG). On a separate day, the patient's brain will be imaged usi...
What is the current status of trial NCT01543633?
This trial is currently completed. It is a NA study. The enrollment target is 36 participants. The study started on 2005-08. Estimated completion is 2020-07.
What conditions does trial NCT01543633 study?
This clinical trial studies the following conditions: Brain Activity Under Sedation.
What interventions are being tested in trial NCT01543633?
The interventions under investigation include: Propofol (DRUG).
Who is sponsoring clinical trial NCT01543633?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01543633 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01543633's enrollment target sits among peer trials
36 1541st of 2000 higher than 437 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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