Inovio Pharmaceuticals

Closed portfolio with an early-phase archive tilt

According to ClinicalTrials.gov-derived indexes, Inovio Pharmaceuticals sits in the top decile of US sponsors by registered trial count (#568 of 15,742 sponsors by registered trial count).

28 total trials none currently recruiting 24 completed early-phase tilt top decile by trial count

Inovio Pharmaceuticals: 28 sponsored US clinical trials, none currently recruiting.

Inovio Pharmaceuticals sponsors 28 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 24 completed. 6 of these trials are in Phase 3-4 (later-stage) and 22 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HSIL, with 2 trials.

Top-decile sponsor footprint

Inovio Pharmaceuticals ranks in the top decile of sponsors by registered trial count (#568 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 62/100

24 of 27 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Indexed trials (enrollment closed)

28 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 1

INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)

NCT03491683

TERMINATED Phase 2

Safety, Immunogenicity, and Efficacy of INO-4800 for COVID-19 in Adults at High Risk of SARS-CoV-2 Exposure

NCT04642638

COMPLETED Phase 1

INO-3107 With Electroporation (EP) in Participants With HPV-6- and/or HPV-11-Associated Recurrent Respiratory Papillomatosis (RRP)

NCT04398433

COMPLETED Phase 1

Safety, Tolerability and Immunogenicity of INO-4800 for COVID-19 in Healthy Volunteers

NCT04336410

COMPLETED Phase 1

Safety, Tolerability and Immunogenicity of INO-4500 in Healthy Volunteers

NCT03805984

COMPLETED Phase 3

REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)

NCT03721978

COMPLETED Phase 1

INO-5401 + INO-9012 in Combination With Atezolizumab in Locally Advanced Unresectable or Metastatic/Recurrent Urothelial Carcinoma

NCT03502785

COMPLETED Phase 2

VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2

NCT03499795

COMPLETED Phase 2

Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)

NCT03180684

COMPLETED Phase 3

REVEAL 1 (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)

NCT03185013

COMPLETED Phase 1

Trial to Evaluate Safety and Immunogenicity of INO-5150 Alone or With INO-9012 in Men With Prostate Cancer

NCT02514213

COMPLETED Phase 1

Open-Label Study of INO-4212 With or Without INO-9012, Administered IM or ID Followed by Electroporation in Healthy Volunteers

NCT02464670

COMPLETED Phase 1

Phase I Study of INO-1800 With or Without INO-9112 + EP in Chronic Hepatitis B Subjects

NCT02431312

COMPLETED Phase 1

hTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of Relapse

NCT02960594

COMPLETED Phase 1

Study of HPV Specific Immunotherapy in Participants With HPV Associated Head and Neck Squamous Cell Carcinoma

NCT02163057

COMPLETED Phase 1

A Study of INO-3112 DNA Vaccine With Electroporation in Participants With Cervical Cancer

NCT02172911

COMPLETED Phase 1

Immunotherapy in Subjects With HPV-6 Associated Aerodigestive Precancerous Lesions and Malignancies

NCT02241369

COMPLETED Phase 1

A Study of DNA Vaccine With Electroporation for the Prevention of Disease Caused by H1 and H5 Influenza Virus

NCT01405885

COMPLETED Phase 1

A Follow-On Study With an H5 Influenza Vaccine for Subjects Who Participated in Study FLU-001

NCT01403155

COMPLETED Phase 2

A Study of VGX-3100 DNA Vaccine With Electroporation in Patients With Cervical Intraepithelial Neoplasia Grade 2/3 or 3

NCT01304524

COMPLETED Phase 1

Study of PENNVAX™-B (Gag, Pol, Env) + Electroporation in HIV-1 Infected Adult Participants

NCT01082692

COMPLETED Phase 1

Fourth Dose of Human Papillomavirus (HPV) DNA Plasmid (VGX-3100) + EP in Adult Females Previously Vaccinated With Three Doses of VGX-3100

NCT01188850

COMPLETED Phase 1

Study of VGX-3400X, H5N1 Avian Influenza Virus DNA Plasmid + Electroporation in Healthy Adults

NCT01142362

COMPLETED Phase 1

Phase I of Human Papillomavirus (HPV) DNA Plasmid (VGX-3100) + Electroporation for CIN 2 or 3

NCT00685412

TERMINATED Phase 3

Medpulser Electroporation With Bleomycin Study to Treat Posterior Head and Neck Squamous Cell Carcinoma

NCT00198328

TERMINATED Phase 3

Medpulser Electroporation With Bleomycin Study to Treat Anterior Head and Neck Squamous Cell Carcinoma

NCT00198315

COMPLETED Phase 4

Study Using the MedPulser Electroporation System With Bleomycin to Treat Cutaneous and Subcutaneous Cancer

NCT00198276

COMPLETED Phase 4

Study Using the Medpulser Electroporation System With Bleomycin to Treat Head and Neck Cancer

NCT00198263

Phase Distribution

PhaseTrial count
Phase 1 18
Phase 2 4
Phase 3 4
Phase 4 2

How the Inovio Pharmaceuticals early-phase archive is shaped

28 indexed studies, none listed as recruiting (0% open); 24 completed (86%).

Phase mix: 6 late (III/IV) vs 22 early (I/II) (early-phase heavy).

Top condition: HSIL (2 trials), 6 others listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

Inovio Pharmaceuticals: archived-pipeline peers nationwide

Peers matched on 28 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

Inovio Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0102030 0%5%10%15%20%25% Total trials Recruiting share Inovio PharmaceuticalsAxsome TherapeuticsBenaroya Research InstituteCAMC Health SystemCTI BioPharma10xBio22nd Century Group23andMe3-C Institute for Social Development
Inovio Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Inovio Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 28 archived trials

Sponsors with similar archive density (± trial count)

What to do with this Inovio Pharmaceuticals page

28 registered trials is a research-attention snapshot, not an endorsement of Inovio Pharmaceuticals or any single study.

  • None of Inovio Pharmaceuticals's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • HSIL is the condition Inovio Pharmaceuticals studies most, compare against other sponsors active in the same condition before evaluating a specific study. See HSIL trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Inovio Pharmaceuticals pipeline card: 28 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.