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NCT01405885 · ClinicalTrials.gov registry record · Phase 1

A Study of DNA Vaccine With Electroporation for the Prevention of Disease Caused by H1 and H5 Influenza Virus

A Phase 1 study, sponsored by Inovio Pharmaceuticals.

Completed
Registry status
Phase 1
Development phase
116
Enrollment target

NCT01405885: Completed Phase 1 study, sponsored by Inovio Pharmaceuticals.

NCT01405885 is a Phase 1 study that has completed, run by Inovio Pharmaceuticals. The registered enrollment target is 116 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01405885, a Phase 1 study, has completed, sponsored by Inovio Pharmaceuticals.

COMPLETED
Registry status
Phase 1
Development phase
116 participants
Enrollment target

Study Summary

This is a Phase I, parallel design open label study to evaluate safety, tolerability and immunogenicity of nine different formulation of two individual H1 and one H5 HA plasmid administered intradermally followed by electroporation in healthy adults

Primary Outcome

Frequency and severity of local and systemic reactogenicity signs and symptoms, adverse events and serious adverse events

Interventions

  • BIOLOGICAL INO-3605
  • BIOLOGICAL INO-3609
  • BIOLOGICAL INO-3401
  • BIOLOGICAL INO-3605 AND INO-3609

Trial Details

FieldValue
Enrollment Target 116 participants
Start Date 2011-05
Est. Completion 2013-08
Phase Phase 1
Inovio Pharmaceuticals

28 total trials

What the finished NCT01405885 record still lists

NCT01405885 is an interventional study that assigns participants to a tested intervention. The registered 116 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% higher).

The record links to 0 conditions, and to 4 interventions - of which INO-3605 is the first listed.

NCT01405885 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01405885 about?

NCT01405885 is a clinical study titled "A Study of DNA Vaccine With Electroporation for the Prevention of Disease Caused by H1 and H5 Influenza Virus". This is a Phase I, parallel design open label study to evaluate safety, tolerability and immunogenicity of nine different formulation of two individual H1 and one H5 HA plasmid administered intradermally followed by electroporation in healthy adults

What is the current status of trial NCT01405885?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 116 participants. The study started on 2011-05. Estimated completion is 2013-08.

What interventions are being tested in trial NCT01405885?

The interventions under investigation include: INO-3605 (BIOLOGICAL), INO-3609 (BIOLOGICAL), INO-3401 (BIOLOGICAL), INO-3605 AND INO-3609 (BIOLOGICAL).

Who is sponsoring clinical trial NCT01405885?

This trial is sponsored by Inovio Pharmaceuticals, which has 28 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01405885's enrollment target sits among peer trials

116 501st of 2000 higher than 1,497 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01405885, the US trial registry maintained by the National Library of Medicine. NCT01405885 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.