Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00198328 · ClinicalTrials.gov registry record · Phase 3

Medpulser Electroporation With Bleomycin Study to Treat Posterior Head and Neck Squamous Cell Carcinoma

A Phase 3 study, sponsored by Inovio Pharmaceuticals.

Terminated
Registry status
Phase 3
Development phase
84
Enrollment target

NCT00198328: Clinical Trial Phase 3 study, sponsored by Inovio Pharmaceuticals.

NCT00198328 is a Phase 3 study that was terminated before completion, run by Inovio Pharmaceuticals. The registered enrollment target is 84 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00198328, a Phase 3 study, was terminated before completion, sponsored by Inovio Pharmaceuticals.

TERMINATED
Registry status
Phase 3
Development phase
84 participants
Enrollment target

Study Summary

The purpose of the study is to evaluate Medpulser electroporation (EPT) with bleomycin with regard to local tumor recurrence, disease-free survival, and overall survival rates versus surgery in recurrent or secondary primary squamous cell carcinoma (SCC) of the base of the tongue, posterior lateral pharyngeal wall, hypopharynx or larynx.

Interventions

  • COMBINATION_PRODUCT Medpulser Electroporation with Bleomycin
  • PROCEDURE Surgical Excision

Trial Details

FieldValue
Enrollment Target 84 participants
Start Date 2004-11
Est. Completion 2007-06
Phase Phase 3
Inovio Pharmaceuticals

28 total trials

Why NCT00198328 stopped before completion

NCT00198328 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (89% lower).

The record links to 0 conditions, and to 2 interventions - of which Medpulser Electroporation with Bleomycin is the first listed.

NCT00198328 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00198328 about?

NCT00198328 is a clinical study titled "Medpulser Electroporation With Bleomycin Study to Treat Posterior Head and Neck Squamous Cell Carcinoma". The purpose of the study is to evaluate Medpulser electroporation (EPT) with bleomycin with regard to local tumor recurrence, disease-free survival, and overall survival rates versus surgery in recurrent or secondary primary squamous cell carcinoma (SCC) of the base of the tongue, posterior lateral ...

What is the current status of trial NCT00198328?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 84 participants. The study started on 2004-11. Estimated completion is 2007-06.

What interventions are being tested in trial NCT00198328?

The interventions under investigation include: Medpulser Electroporation with Bleomycin (COMBINATION_PRODUCT), Surgical Excision (PROCEDURE).

Who is sponsoring clinical trial NCT00198328?

This trial is sponsored by Inovio Pharmaceuticals, which has 28 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00198328's enrollment target sits among peer trials

84 1749th of 2000 higher than 250 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02391519 · 84 participants

    Effects of High Altitude on AMPK Activation

  • NCT03838536 · 84 participants · NA

    Synergistic Activity of Human Milk Nutrients and Infant Cognition

  • NCT03884075 · 84 participants · Phase 2

    Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)

  • NCT03894917 · 84 participants

    Characterizing Disease Biology, Treatment and Toxicity in Older Adults With Hepatocellular Carcinoma

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00198328, the US trial registry maintained by the National Library of Medicine. NCT00198328 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.