Genzyme, a Sanofi Company

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Genzyme, a Sanofi Company sits in the top decile of US sponsors by registered trial count (#154 of 15,742 sponsors by registered trial count).

196 total trials 4 currently recruiting 159 completed early-phase tilt top decile by trial count

Genzyme, a Sanofi Company: 196 sponsored US clinical trials, 4 recruiting.

Genzyme, a Sanofi Company sponsors 196 registered US clinical trials on ClinicalTrials.gov, 4 of them currently recruiting, and 159 completed. 65 of these trials are in Phase 3-4 (later-stage) and 114 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Glycogen Storage Disease Type II (GSD-II), with 5 trials.

Top-decile sponsor footprint

Genzyme, a Sanofi Company ranks in the top decile of sponsors by registered trial count (#154 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 51/100

159 of 188 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (84.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

196 total, page 3 of 4

COMPLETED Phase 3

A New Study to Follow-up Thyroid Cancer Patients Who Participated in a Previous Study, Which Compared the Success of Destruction of the Thyroid Remnant Using Standard Treatment or Thyrogen.

NCT00295763

TERMINATED Phase 2

Comparison Study of Rituximab Plus Sargramostim to Rituximab Alone for Relapsed Follicular B-cell Lymphoma, a Form of Non-Hodgkin's Lymphoma

NCT00308087

COMPLETED Phase 1

A Study of Clofarabine in Combination With Etoposide and Cyclophosphamide in Children With Acute Leukemias.

NCT00315705

COMPLETED Phase 2

The Effect of Rituximab on Mobilization With AMD3100 (Plerixafor) Plus G-CSF in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) or Hodgkin Disease (HD)

NCT00444912

COMPLETED Phase 4

A Post-Market Study to Evaluate Adverse Event Incidence Rates in Patients With Skin of Color Undergoing Correction of Nasolabial Folds With Hylaform, Hylaform Plus and Captique.

NCT00293163

COMPLETED Phase 1

Safety, Pharmacokinetics (PK), And Hematological Activity Of AMD3100 (Plerixafor) In Subjects With Renal Impairment

NCT00445302

COMPLETED Phase 3

Study to Compare Sevelamer Carbonate Powder to Sevelamer Hydrochloride Tablets in Patients With CKD on Hemodialysis

NCT00268957

TERMINATED Phase 3

Efficacy (Induction of Response/Remission) and Safety Study in Patients With Moderate to Severe Crohn's Disease

NCT00295165

COMPLETED Phase 1

A Study of AMD11070 in HIV-infected Patients Carrying X4-tropic Virus

NCT00361101

COMPLETED Phase 2

AMD3100 (Plerixafor) With G-CSF in Poor Mobilizing Adult Patients Who Previously Failed Hematopoietic Stem Cell (HSC) Collection/Attempts

NCT00396331

COMPLETED Phase 3

A Placebo-Controlled Study of Safety and Effectiveness of Myozyme (Alglucosidase Alfa) in Patients With Late-Onset Pompe Disease

NCT00158600

TERMINATED Phase 1

Safety Study of GMA161 in Patients With Idiopathic Thrombocytopenic Purpura (ITP)

NCT00244257

COMPLETED Phase 4

Study of Safety and Efficacy of Doxercalciferol in Patients With Chronic Kidney Disease, Stage 3 or 4, and Secondary Hyperparathyroidism

NCT00123461

COMPLETED Phase 1

Study of GC1008 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

NCT00125385

COMPLETED Phase 2

Extension Study of Patients With Infantile-Onset Pompe Disease Who Were Previously Enrolled in Protocol AGLU01602

NCT00125879

COMPLETED Phase 1

Study Comparing Thyrogen Versus a Modified Release of Recombinant Human Thyroid Stimulating Hormone

NCT00137891

COMPLETED

Screening Protocol to Evaluate Acid Alpha-Glucosidase (GAA) Activity and GAA Gene Mutations in Patients With Late Onset Pompe Disease

NCT00113035

COMPLETED Phase 2

Alemtuzumab/Fludarabine for Relapsed/Refractory B-cell Chronic Lymphocytic Leukemia (B-CLL)

NCT00206726

COMPLETED Phase 2

Evaluation of Thymoglobulin Induction and Reduced Doses of Calcineurin Inhibitors on Liver Transplant Rejection

NCT00117689

TERMINATED Phase 2

AMD3100 (Plerixafor) in Multiple Myeloma (MM) or Non-Hodgkin's Lymphoma (NHL) Patients Predicted to be Unable to Mobilize With G-CSF Alone

NCT00395967

COMPLETED Phase 2

Cross-Over Study of Sevelamer Hydrochloride and Sevelamer Carbonate

NCT00440648

COMPLETED Phase 3

A Study of GT267-004 Versus Vancomycin and GT267-004 Versus Metronidazole in Patients With C.Difficile - Associated Diarrhea

NCT00106509

COMPLETED Phase 2

Safety and Efficacy Study of Ad2/Hypoxia Inducible Factor (HIF)-1α/VP16 Gene Transfer in Patients With Intermittent Claudication

NCT00117650

COMPLETED Phase 3

Mobilization of Stem Cells With AMD3100 (Plerixafor) in Non-Hodgkin's Lymphoma Patients

NCT00103610

COMPLETED Phase 3

Mobilization of Stem Cells With AMD3100 (Plerixafor) in Multiple Myeloma Patients

NCT00103662

TERMINATED Phase 1

Safety and Efficacy Study in the Treatment of Pediatric Crohn's Disease

NCT00206661

COMPLETED Phase 2

Efficacy and Tolerability of ZD6474 in Patients With Thyroid Cancer

NCT00098345

COMPLETED NA

Expanded Access Use of Myozyme (Alglucosidase Alfa) in Patients With Late-onset Pompe Disease

NCT00074932

COMPLETED Phase 2

AMD3100 (Plerixafor) Added to a Mobilizing Regimen of Granulocyte-colony Stimulating Factor (G-CSF) to Increase the Number of Peripheral Blood Stem Cells (PBSCs) in Patients With Hodgkin's Disease

NCT00396201

COMPLETED Phase 1

A Study of AAV-hAADC-2 in Subjects With Parkinson's Disease

NCT00229736

TERMINATED Phase 2

Treatment With AMD3100 (Plerixafor) in MM Patients to Mobilize PBCs For Collection and for Transplantation

NCT00396383

COMPLETED Phase 3

Comparison of Hylastan to Methylprednisolone Acetate in Patients With Symptomatic Osteoarthritis of the Knee

NCT00139295

COMPLETED Phase 4

A Study Investigating the Relationship Between the Development of Laronidase Antibody and Urinary GAG (Glycosaminoglycan) Levels in Aldurazyme® Treated Patients

NCT00144768

COMPLETED Phase 3

Fludarabine (Fludara®) Plus Alemtuzumab (CAMPATH®, MabCampath®) vs Fludarabine Alone in B-Cell Chronic Lymphocytic Leukemia (B-CLL) Patients

NCT00086580

TERMINATED Phase 3

Efficacy Study of Sargramostim in the Retreatment of Patients Who Have Crohn's Disease Who Have Previously Responded to Treatment With Sargramostim

NCT00206713

COMPLETED Phase 2

Mobilization of Stem Cells With Plerixafor, Chemotherapy and G-CSF in Multiple Myeloma or Non-Hodgkin's Lymphoma Patients

NCT00322387

COMPLETED NA

Thymoglobulin to Prevent Acute Graft vs. Host Disease (GvHD) in Patients With Acute Lymphocytic Leukemia (ALL) or Acute Myelogenous Leukemia (AML) Receiving a Stem Cell Transplant

NCT00088543

COMPLETED Phase 2

Mobilization of Stem Cells With AMD3100 (Plerixafor) and G-CSF in Non-Hodgkin's Lymphoma and Multiple Myeloma Patients

NCT00322491

COMPLETED Phase 2

Trilostane for Androgen-Independent Prostate Cancer

NCT00181597

COMPLETED

A Prospective, Observational Study in Patients With Late-Onset Pompe Disease

NCT00077662

TERMINATED Phase 1

A Safety and Efficacy Study of DENSPM in Patients With Liver Cancer Who Are Not Eligible for Surgical Care

NCT00081900

COMPLETED Phase 2

ZD6474 Alone or in Combination With Paclitaxel and Carboplatin in Subjects With Previously Untreated Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)

NCT00071188

COMPLETED Phase 4

A Study of the Safety and Efficacy of Fabrazyme in Patients With Fabry Disease

NCT00081497

COMPLETED Phase 2

Study of ILX651 in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Carcinoma

NCT00078455

TERMINATED Phase 1

Subcutaneously Administered CAMPATH in CD52 Expressing Hematologic Malignancies

NCT00113048

TERMINATED Phase 1

Rituximab Plus CAMPATH in Patients With Relapsed/Refractory Low-Grade or Follicular, CD20-positive, B-cell NHL

NCT00077961

COMPLETED

Mucopolysaccharidosis I (MPS I) Registry

NCT00144794

COMPLETED Phase 3

A Study of the Safety and Efficacy of Synvisc and Depo-Medrol in Patients With Osteoarthritis of the Hip

NCT00131326

COMPLETED Phase 1

Study of Oral Clofarabine Administered Daily for 5 Days in Adult Patients With Refractory Solid Tumors

NCT00125827

COMPLETED Phase 1

Iron Balance Study of DFO and GT56-252 in Patients With Transfusional Iron Overload Secondary to Beta-Thalassemia

NCT00069862

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What is open in the Genzyme, a Sanofi Company pipeline

4 recruiting of 196 indexed (2% open); 159 completed (81%).

Phase mix: 65 late (III/IV) vs 114 early (I/II) (early-phase heavy).

Top condition: Glycogen Storage Disease Type II (GSD-II) (5 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Genzyme, a Sanofi Company: open-pipeline peers nationwide

Peers matched on 196 registered trials and 2% open enrollment, not the therapeutic-area sidebar.

Genzyme, a Sanofi Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 050100150200250 0%5%10%15%20% Total trials Recruiting share Genzyme, a Sanofi CompanyHospital for Special Surgery, New YorkVertex Pharmaceuticals IncorporatedNational Center for Complementary and Integrative Health (NCCIH)The University of Texas Medical Branch, GalvestonCynosureCarelon ResearchSun Pharmaceutical IndustriesSanofi Pasteur, a Sanofi Company
Genzyme, a Sanofi Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Genzyme, a Sanofi Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 196 trials (± recruiting share)

Sponsors near 2% open enrollment (± trial volume)

What to do with this Genzyme, a Sanofi Company page

196 registered trials is a research-attention snapshot, not an endorsement of Genzyme, a Sanofi Company or any single study.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Genzyme, a Sanofi Company pipeline card: 196 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.