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NCT00098345 · ClinicalTrials.gov registry record · Phase 2
Efficacy and Tolerability of ZD6474 in Patients With Thyroid Cancer
A Phase 2 study, sponsored by Genzyme, a Sanofi Company.
- Completed
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
NCT00098345: Completed Phase 2 study, sponsored by Genzyme, a Sanofi Company.
NCT00098345 is a Phase 2 study that has completed, run by Genzyme, a Sanofi Company. The registered enrollment target is 40 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00098345, a Phase 2 study, has completed, sponsored by Genzyme, a Sanofi Company.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
Study Summary
The purpose of this open label, two stage, phase II study is to evaluate the efficacy and tolerability of ZD6474 in patients with locally advanced or metastatic hereditary medullary thyroid carcinoma.
Primary Outcome
The ORR is the number of patients that are responders ie those patients with a confirmed best objective response of complete response (CR) or partial response (PR) defined according to RECIST 1.0.
Interventions
- DRUG ZD6474 (vandetanib)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2004-11 |
| Est. Completion | 2017-04-19 |
| Phase | Phase 2 |
What the finished NCT00098345 record still lists
NCT00098345 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 1 intervention - of which ZD6474 (vandetanib) is the first listed.
NCT00098345 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00098345 about?
NCT00098345 is a clinical study titled "Efficacy and Tolerability of ZD6474 in Patients With Thyroid Cancer". The purpose of this open label, two stage, phase II study is to evaluate the efficacy and tolerability of ZD6474 in patients with locally advanced or metastatic hereditary medullary thyroid carcinoma.
What is the current status of trial NCT00098345?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2004-11. Estimated completion is 2017-04-19.
What interventions are being tested in trial NCT00098345?
The interventions under investigation include: ZD6474 (vandetanib) (DRUG).
Who is sponsoring clinical trial NCT00098345?
This trial is sponsored by Genzyme, a Sanofi Company, which has 196 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00098345's enrollment target sits among peer trials
40 1362nd of 2000 higher than 542 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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