Genzyme, a Sanofi Company

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Genzyme, a Sanofi Company sits in the top decile of US sponsors by registered trial count (#154 of 15,742 sponsors by registered trial count).

196 total trials 4 currently recruiting 159 completed early-phase tilt top decile by trial count

Genzyme, a Sanofi Company: 196 sponsored US clinical trials, 4 recruiting.

Genzyme, a Sanofi Company sponsors 196 registered US clinical trials on ClinicalTrials.gov, 4 of them currently recruiting, and 159 completed. 65 of these trials are in Phase 3-4 (later-stage) and 114 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Glycogen Storage Disease Type II (GSD-II), with 5 trials.

Top-decile sponsor footprint

Genzyme, a Sanofi Company ranks in the top decile of sponsors by registered trial count (#154 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 51/100

159 of 188 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (84.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

196 total, page 4 of 4

COMPLETED Phase 2

Study of ILX651 in Patients With Inoperable Locally Advanced or Metastatic Melanoma

NCT00068211

TERMINATED Phase 1

An Investigation Into the Short Term Effect of APOMINE in Patients With Osteoporosis or Low Bone Mass

NCT00078026

COMPLETED Phase 2

A Study to Evaluate the Effect of Thymoglobulin and Reduced Doses of Steroids to Prevent Renal Transplant Rejection

NCT00089947

TERMINATED NA

Efficacy of Seprapack Sinus Dressing Versus No Dressing in the Prevention of Intranasal Adhesions Following Sinus Surgery

NCT00140608

COMPLETED Phase 2

This Study is to Compare the Efficacy of ZD6474 and ZD1839 in Subjects With NSCLC.

NCT00059722

COMPLETED Phase 2

Extension Study of Long-term Safety and Efficacy of Myozyme for a Single Patient With Pompe Disease Who Were Previously Enrolled in Genzyme Sponsored ERT Studies.

NCT00765414

COMPLETED Phase 2

Extension Study of Long-term Safety and Efficacy of Myozyme in Patients With Pompe Disease Who Were Previously Enrolled in Genzyme Sponsored Enzyme Replacement Therapy (ERT) Studies

NCT00763932

COMPLETED Phase 2

A Study of the Safety and Efficacy of rhGAA in Patients With Infantile-onset Pompe Disease

NCT00059280

COMPLETED Phase 2

Study to Compare Once A Day Sevelamer Dosing With Three Times Per Day Sevelamer Dosing

NCT00324376

COMPLETED Phase 1

rhGAA in Patients With Infantile-onset Glycogen Storage Disease-II (Pompe Disease)

NCT00053573

TERMINATED Phase 2

Open-label Trial of Leukine in Active Crohn's Disease

NCT00206700

COMPLETED Phase 2

A Study of the Safety and Pharmacokinetics of rhGAA in Siblings With Glycogen Storage Disease Type II

NCT00051935

COMPLETED Phase 2

A Phase II Study Comparing Low- and High-Dose Alemtuzumab and High-Dose Rebif® in Patients With Early, Active Relapsing-Remitting Multiple Sclerosis

NCT00050778

TERMINATED Phase 1

Phase I/II Study of CAMPATH in Patients With Relapsing or Refractory Non-Hodgkin's Lymphoma

NCT00051701

TERMINATED Phase 2

Severe Renal Disease Study in Fabry Patients Treated With Fabrazyme

NCT00837824

COMPLETED Phase 1

Safety/Efficacy of a Vaccine Prepared From Dendritic Cells Combined With Tumor Cells to Treat Advanced Kidney Cancer

NCT00050323

COMPLETED Phase 2

This Study is to Assess the Efficacy and Safety of ZD6474 in Subjects With Non-small Cell Lung Cancer.

NCT00047840

COMPLETED Phase 2

A Study of Fabrazyme in Pediatric Patients With Fabry Disease

NCT00074958

COMPLETED Phase 2

Efficacy Study of ZD6474 to Treat Multiple Myeloma Cancer

NCT00047788

COMPLETED Phase 1

Clofarabine in Adult Patients With Advanced Solid Tumors

NCT00125840

COMPLETED Phase 2

Phase II Study of Clofarabine in Pediatric Acute Lymphoblastic Leukemia (ALL)

NCT00042341

COMPLETED Phase 2

Phase II Study of Clofarabine in Adult Patients With Refractory or Relapsed Acute Myelogenous Leukemia

NCT00044889

COMPLETED Phase 2

Phase II Study of Clofarabine in Pediatric Acute Myelogenous Leukemia (AML) Patients

NCT00042354

COMPLETED Phase 2

This Study is to Assess the Efficacy and Safety of ZD6474 in Subjects With Metastatic Breast Cancer

NCT00034918

COMPLETED Phase 2

A Study of GT160-246 Versus Vancomycin in Patients With Clostridium Difficile-Associated Diarrhea

NCT00034294

COMPLETED Phase 4

Safety and Efficacy of Cerezyme® Infusions Every 4 Weeks Versus Every 2 Weeks in Type 1 Gaucher Disease

NCT00364858

COMPLETED Phase 3

Efficacy/Safety of Frontline Alemtuzumab (Campath, MabCampath) vs Chlorambucil in Patients With Progressive B-Cell Lymphocytic Leukemia

NCT00046683

COMPLETED Phase 1

A Study of NM-3 Administered Orally in Patients With Advanced Solid Tumors.

NCT00046696

COMPLETED Phase 2

Safety and Efficacy of Recombinant Human Acid Alpha-Glucosidase in the Treatment of Classical Infantile Pompe Disease

NCT00025896

COMPLETED Phase 3

Phase 3 Extension Study of the Safety and Efficacy of Aldurazyme® (Laronidase) in Mucopolysaccharidosis I (MPS I) Patients

NCT00146770

COMPLETED Phase 4

Dialysis Clinical Outcomes Revisited (DCOR) Trial

NCT00324571

COMPLETED Phase 4

A Study of the Safety and Efficacy of Fabrazyme (Agalsidase Beta) as Compared to Placebo in Patients With Advanced Fabry Disease

NCT00074984

COMPLETED Phase 3

Clinical Study of Aldurazyme in Patients With Mucopolysaccharidosis (MPS) I

NCT00912925

COMPLETED Phase 2

Antithymocyte Globulin Compared With Supportive Care in Treating Patients With Myelodysplastic Syndrome

NCT00017550

COMPLETED Phase 2

An Open-label, Prospective, Randomized, Multi-center, Phase II Comparative Trial of Thymoglobulin Versus Simulect for the Prevention of Delayed Graft Function and Acute Allograft Rejection in Renal Allograft Recipients.

NCT00235300

COMPLETED Phase 3

A Study of the Safety and Efficacy of Fabrazyme in Patients With Fabry Disease

NCT00074971

COMPLETED Phase 1

SR-45023A in Treating Patients With Locally Advanced or Metastatic Solid Tumors

NCT00004049

COMPLETED Phase 1

SR-45023A in Treating Patients With Advanced Solid Tumors

NCT00003822

COMPLETED NA

Seprafilm in the Reduction of Incidence of Bowel Obstruction in General Surgery

NCT00130715

COMPLETED Phase 4

A Multicenter Study of the Efficacy of Cerezyme in Testing Skeletal Disease in Patients With Type I Gaucher Disease.

NCT00365131

COMPLETED Phase 2

Phase 2, Double-blind, Randomized, Controlled Multi-center Clinical Trial of the Safety and Efficacy of Transplanted Fetal Porcine Cells in Patients With Parkinson's Disease.

NCT00226460

COMPLETED Phase 1

Chemotherapy in Treating Patients With Advanced or Metastatic Solid Tumors

NCT00003713

COMPLETED Phase 2

Aminopterin in Treating Patients With Refractory Leukemia

NCT00003305

COMPLETED Phase 1

Safety, Tolerability, and Pharmacokinetics of CAT-192 (Human Anti-TGF-Beta1 Monoclonal Antibody) in Patients With Early Stage Diffuse Systemic Sclerosis

NCT00043706

COMPLETED Phase 2

Study of ILX651 in Patients With Hormone-Refractory Prostate Cancer Previously Treated With Docetaxel

NCT00082134

COMPLETED Phase 2

A Study of Mitoguazone Dihydrochloride in Patients With AIDS-Related Non-Hodgkin's Lymphoma

NCT00002348

← Previous Page 4 of 4

What is open in the Genzyme, a Sanofi Company pipeline

4 recruiting of 196 indexed (2% open); 159 completed (81%).

Phase mix: 65 late (III/IV) vs 114 early (I/II) (early-phase heavy).

Top condition: Glycogen Storage Disease Type II (GSD-II) (5 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Genzyme, a Sanofi Company: open-pipeline peers nationwide

Peers matched on 196 registered trials and 2% open enrollment, not the therapeutic-area sidebar.

Genzyme, a Sanofi Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 050100150200250 0%5%10%15%20% Total trials Recruiting share Genzyme, a Sanofi CompanyHospital for Special Surgery, New YorkVertex Pharmaceuticals IncorporatedNational Center for Complementary and Integrative Health (NCCIH)The University of Texas Medical Branch, GalvestonCynosureCarelon ResearchSun Pharmaceutical IndustriesSanofi Pasteur, a Sanofi Company
Genzyme, a Sanofi Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Genzyme, a Sanofi Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 196 trials (± recruiting share)

Sponsors near 2% open enrollment (± trial volume)

What to do with this Genzyme, a Sanofi Company page

196 registered trials is a research-attention snapshot, not an endorsement of Genzyme, a Sanofi Company or any single study.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Genzyme, a Sanofi Company pipeline card: 196 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.