Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00139295 · ClinicalTrials.gov registry record · Phase 3
Comparison of Hylastan to Methylprednisolone Acetate in Patients With Symptomatic Osteoarthritis of the Knee
A Phase 3 study of Osteoarthritis, Knee, sponsored by Genzyme, a Sanofi Company.
- Completed
- Registry status
- Phase 3
- Development phase
- 20
- Study locations
NCT00139295: Completed Phase 3 study of Osteoarthritis, Knee, sponsored by Genzyme, a Sanofi Company.
NCT00139295 is a Phase 3 study of Osteoarthritis, Knee that has completed, run by Genzyme, a Sanofi Company. The trial reports 20 study locations across 14 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00139295, a Phase 3 study of Osteoarthritis, Knee, has completed, sponsored by Genzyme, a Sanofi Company.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 20
- Study locations
Study Summary
This is a clinical study to investigate the safety and efficacy of hylastan in treating patients with symptomatic osteoarthritis (OA) of the knee.
Conditions Studied
Interventions
- DEVICE Hylastan
Study Locations (20)
Other
- Clinique du Sport - Mérignac
- Centre Hospitalier Lyon-Sud, Service de Rhumatologie - Pierre-Bénite
- CHU Hôpital Trousseau Service de Rhumatologie - Tours
- St-Elisabeth Klinik, Orthopädisch Gemeinschaftspraxis - Heidelberg
Illinois
- Northwestern Center for Clinical Research - Chicago
- Midwest Orthopedics at Rush University Medical Center - Chicago
- Rockford Health Physicians - Rockford
Arizona
- Hope Research Institute, LLC - Phoenix
- Tucson Orthopedic Institute, PC - Tucson
Alabama
- Capstone Clinical Trials, Inc - Birmingham
Florida
- Orthopaedic Specialties of Tampa Bay - Clearwater
Kentucky
- Bluegrass Orthopaedics/Bluegrass Musculoskeletal Research - Lexington
Louisiana
- Orthopedic Specialists of Louisiana - Shreveport
Maryland
- Arthritis & Osteoporosis Center of Maryland - Frederick
Trial Details
| Field | Value |
|---|---|
| Start Date | 2004-10 |
| Est. Completion | 2007-09 |
| Phase | Phase 3 |
What the finished NCT00139295 record still lists
NCT00139295 is an interventional study that assigns participants to a tested intervention. An enrollment target was not published in the registry record, which is common for early-stage or observational entries.
The record links to 1 condition, with Osteoarthritis, Knee appearing as the primary indexed condition, and to 1 intervention - of which Hylastan is the first listed.
NCT00139295 names 20 study sites across 14 states, led by Other, Illinois, Arizona.
Frequently Asked Questions
What is clinical trial NCT00139295 about?
NCT00139295 is a clinical study titled "Comparison of Hylastan to Methylprednisolone Acetate in Patients With Symptomatic Osteoarthritis of the Knee". This is a clinical study to investigate the safety and efficacy of hylastan in treating patients with symptomatic osteoarthritis (OA) of the knee.
What is the current status of trial NCT00139295?
This trial is currently completed. It is a Phase 3 study. The study started on 2004-10. Estimated completion is 2007-09.
What conditions does trial NCT00139295 study?
This clinical trial studies the following conditions: Osteoarthritis, Knee.
What interventions are being tested in trial NCT00139295?
The interventions under investigation include: Hylastan (DEVICE).
Who is sponsoring clinical trial NCT00139295?
This trial is sponsored by Genzyme, a Sanofi Company, which has 196 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00139295 being conducted?
This trial has 20 study locations across Alabama, Arizona, Florida, Illinois, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis, Knee
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
A Study to Investigate the Treatment Effect of Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain.
RECRUITING · Phase 3
-
Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans
RECRUITING · Phase 3
-
A Study to Evaluate Efficacy and Safety of AMZ001 for the Treatment of Knee Osteoarthritis Symptoms
ACTIVE NOT RECRUITING · Phase 3
-
Autologous Adipose-derived Stromal Vascular Fraction for Treatment of Knee Osteoarthritis
ACTIVE NOT RECRUITING · Phase 3
-
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight
ACTIVE NOT RECRUITING · Phase 3
-
Microfragmented Adipose Tissue Compared to Saline Injection for the Treatment of Knee Osteoarthritis
ACTIVE NOT RECRUITING · Phase 3
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia