EyePoint Pharmaceuticals

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, EyePoint Pharmaceuticals sits in the top decile of US sponsors by registered trial count (#886 of 15,742 sponsors by registered trial count).

16 total trials 3 currently recruiting 9 completed top decile by trial count

EyePoint Pharmaceuticals: 16 sponsored US clinical trials, 3 recruiting.

EyePoint Pharmaceuticals sponsors 16 registered US clinical trials on ClinicalTrials.gov, 3 of them currently recruiting, and 9 completed. 8 of these trials are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Diabetic Macular Edema, with 3 trials.

Top-decile sponsor footprint

EyePoint Pharmaceuticals ranks in the top decile of sponsors by registered trial count (#886 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 44/100

9 of 11 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

16 total, page 1 of 1

RECRUITING Phase 3

COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

NCT07449936

RECRUITING Phase 3

CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

NCT07449923

RECRUITING Phase 4

Evaluate the Safety of DEXYCU for the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract

NCT05191706

ACTIVE NOT RECRUITING Phase 3

A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUCIA) Primary Efficacy Will be Determined at Week 56

NCT06683742

ACTIVE NOT RECRUITING Phase 3

A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUGANO) Primary Efficacy Will be Determined at Week 56

NCT06668064

COMPLETED Phase 2

Study of EYP-1901 in Patients With Diabetic Macular Edema (DME)

NCT06099184

COMPLETED Phase 2

Study of EYP-1901 in Patients With Nonproliferative Diabetic Retinopathy (NPDR)

NCT05383209

COMPLETED Phase 2

Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD)

NCT05381948

TERMINATED Phase 3

Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal (FAI) Insert

NCT05070728

COMPLETED Phase 1

First in Human Study to Evaluate the Safety and Tolerability of EYP-1901 in Patients With Wet Age Related Macular Degeneration (wAMD)

NCT04747197

TERMINATED Phase 2

Evaluation of the Safety and Efficacy of Razuprotafib in Hospitalized Subjects With Coronavirus Disease 2019

NCT04511650

COMPLETED Phase 2

Study to Assess the Efficacy, Safety and Tolerability of AKB-9778 Ophthalmic Solution as and Adjunct to Latanoprost in Patients With Ocular Hypertension or Open Angle Glaucoma

NCT04405245

COMPLETED

DEXYCU (Dexamethasone Intraocular Suspension) 9% Retrospective Study 001

NCT04290676

COMPLETED Phase 2

The TIME-2b Study: A Study of AKB-9778 (Razuprotafib), a Novel Tie 2 Activator, in Patients With Non-Proliferative Diabetic Retinopathy (NPDR)

NCT03197870

COMPLETED Phase 3

Utilization and Safety of the Mk II Inserter and the Safety of the FAI Insert in Non-Infectious Uveitis

NCT02748512

COMPLETED Phase 3

Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal Insert

NCT01694186

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 6
Phase 3 7
Phase 4 1

What is open in the EyePoint Pharmaceuticals pipeline

3 recruiting of 16 indexed (19% open); 9 completed (56%).

Phase mix: 8 late (III/IV) vs 7 early (I/II) (balanced across stages).

Top condition: Diabetic Macular Edema (3 trials), 8 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

EyePoint Pharmaceuticals: open-pipeline peers nationwide

Peers matched on 16 registered trials and 19% open enrollment, not the therapeutic-area sidebar.

EyePoint Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%5%10%15%20% Total trials Recruiting share EyePoint PharmaceuticalsAccelerated Community Oncology Research NetworkAltimmuneAmerican UniversityAnthera PharmaceuticalsHebrew SeniorLifeInsulet CorporationUniversity of California, DavisMedical University of South Carolina
EyePoint Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

EyePoint Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 16 trials (± recruiting share)

Sponsors near 19% open enrollment (± trial volume)

What to do with this EyePoint Pharmaceuticals page

16 registered trials is a research-attention snapshot, not an endorsement of EyePoint Pharmaceuticals or any single study.

  • 3 of EyePoint Pharmaceuticals's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Diabetic Macular Edema is the condition EyePoint Pharmaceuticals studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Diabetic Macular Edema trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

EyePoint Pharmaceuticals pipeline card: 16 registered trials from official public datasets.Report a data error.