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NCT07519902 · ClinicalTrials.gov registry record · Phase 3

An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED

A Phase 3 study, sponsored by Dompé Farmaceutici S.p.A.

Recruiting
Registry status
Phase 3
Development phase
150
Enrollment target

NCT07519902: Recruiting Phase 3 study, sponsored by Dompé Farmaceutici S.p.A.

NCT07519902 is a Phase 3 study that is actively recruiting participants, run by Dompé Farmaceutici S.p.A. The registered enrollment target is 150 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07519902, a Phase 3 study, is actively recruiting participants, sponsored by Dompé Farmaceutici S.p.A.

RECRUITING
Registry status
Phase 3
Development phase
150 participants
Enrollment target

Study Summary

This is a phase 3, randomized, multicenter, double-masked, parallel group, vehicle-controlled prospective clinical trial to evaluate the safety and efficacy of cenegermin in inducing complete epithelial healing in participants with PCED. The primary objective is the evaluation of complete epithelial healing after 4 weeks of treatment. The study is comprised of 3 periods: an 8-week initial treatment period (Day 1 to Week 8), an 8-week extension treatment period (Week 9 to Week 16), and a 24-week follow-up period (Week 17 to Week 40).

Interventions

  • OTHER Vehicle
  • DRUG Cenegermin

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2026-06-02
Est. Completion 2027-12
Phase Phase 3
Dompé Farmaceutici S.p.A

27 total trials

What NCT07519902 shows while recruiting

NCT07519902 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (81% lower).

The record links to 0 conditions, and to 2 interventions - of which Vehicle is the first listed.

NCT07519902 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07519902 about?

NCT07519902 is a clinical study titled "An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED". This is a phase 3, randomized, multicenter, double-masked, parallel group, vehicle-controlled prospective clinical trial to evaluate the safety and efficacy of cenegermin in inducing complete epithelial healing in participants with PCED. The primary objective is the evaluation of complete epithelial...

What is the current status of trial NCT07519902?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 150 participants. The study started on 2026-06-02. Estimated completion is 2027-12.

What interventions are being tested in trial NCT07519902?

The interventions under investigation include: Vehicle (OTHER), Cenegermin (DRUG).

Who is sponsoring clinical trial NCT07519902?

This trial is sponsored by Dompé Farmaceutici S.p.A, which has 27 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07519902's enrollment target sits among peer trials

150 1519th of 2000 higher than 455 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07519902, the US trial registry maintained by the National Library of Medicine. NCT07519902 (mid enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.