City of Hope Medical Center

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, City of Hope Medical Center sits in the top decile of US sponsors by registered trial count (#59 of 15,742 sponsors by registered trial count).

582 total trials 167 currently recruiting 217 completed early-phase tilt top decile by trial count

City of Hope Medical Center: 582 sponsored US clinical trials, 167 recruiting.

City of Hope Medical Center sponsors 582 registered US clinical trials on ClinicalTrials.gov, 167 of them currently recruiting, and 217 completed. 9 of these trials are in Phase 3-4 (later-stage) and 382 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Acute Myeloid Leukemia, with 22 trials.

Top-decile sponsor footprint

City of Hope Medical Center ranks in the top decile of sponsors by registered trial count (#59 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 61/100

217 of 245 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

582 total, page 9 of 12

COMPLETED Phase 1

8-Chloroadenosine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT02509546

COMPLETED NA

Electronic Monitoring Device of Patient-Reported Outcomes and Function in Improving Patient-Centered Care in Patients With Gastrointestinal Cancer Undergoing Surgery

NCT02511821

COMPLETED NA

PatientCareAnywhere Internet-Based Software in Improving Communication and Education in Patients With Cancer and Their Healthcare Providers

NCT02408406

TERMINATED NA

Peer-to-Peer Support Program in Improving Quality of Life Outcomes in Patients With Gynecologic Cancer and Their Caregivers

NCT02412124

COMPLETED Phase 1

Total Marrow and Lymphoid Irradiation and Chemotherapy Before Donor Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Leukemia

NCT02446964

COMPLETED Phase 2

Vaccine Therapy in Reducing the Frequency of Cytomegalovirus Events in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

NCT02396134

COMPLETED Early Phase 1

Neuropharmacokinetics of Eribulin Mesylate in Treating Patients With Primary or Metastatic Brain Tumors

NCT02338037

COMPLETED Phase 1

Intra-operative Optical Imaging With MDX1201-A488 in Patients With Prostate Cancer

NCT02048150

COMPLETED NA

Video-Assisted Intervention in Improving Recovery in Patients With Cancer Undergoing Lung Surgery and Caregivers

NCT02345798

COMPLETED NA

Palliative Care Intervention in Improving Symptom Control and Quality of Life in Patients With Stage II-IV Non-small Cell Lung Cancer and Their Family Caregivers

NCT02243748

COMPLETED Phase 1

p53MVA Vaccine and Gemcitabine Hydrochloride in Treating Patients With Recurrent Ovarian Epithelial Cancer

NCT02275039

TERMINATED Phase 3

BEAM vs. 90-Yttrium Ibritumomab Tiuxetan (Zevalin®)/BEAM With ASCT for Relapsed DLBCL

NCT02366663

COMPLETED NA

Video-Based Intervention in Reducing Anxiety in Patients Undergoing Lung Cancer Screening

NCT02288416

COMPLETED NA

64Cu DOTA-Trastuzumab PET/CT in Studying Patients With Gastric Cancer

NCT01939275

COMPLETED NA

Palliative Care in Improving Quality of Life in Patients With Newly Diagnosed Pancreatic Cancer

NCT02307539

COMPLETED Phase 1

Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas

NCT02015819

COMPLETED Phase 1

Eribulin Mesylate and Everolimus in Treating Patients With Triple-Negative Metastatic Breast Cancer

NCT02120469

COMPLETED NA

N2-(1-carboxyethyl)-2'Deoxyguanosine (CEdG) a Potential Biomarker for Diabetes

NCT02065310

COMPLETED NA

Palliative Care Intervention in Improving Quality of Life, Psychological Distress, and Communication in Patients With Solid Tumors Receiving Treatment

NCT01828775

COMPLETED NA

Exercise Intervention in Preventing Breast Cancer Recurrence in Postmenopausal Breast Cancer Survivors

NCT02235051

COMPLETED Phase 1

Diffuse Optical Imaging With Indocyanine Green Solution in Imaging Pelvic Lymph Nodes in Patients With Stage II Prostate Cancer Undergoing Surgery

NCT02119858

COMPLETED Phase 1

Ixazomib Plus Pomalidomide and Dexamethasone in Treating Patients With Relapsed or Relapsed/Refractory Multiple Myeloma

NCT02119468

COMPLETED Phase 1

Chinese Herbal Formulation PHY906 and Sorafenib Tosylate in Treating Patients With Advanced Liver Cancer

NCT01666756

COMPLETED Phase 1

MEK Inhibitor MEK162 in Combination With Leucovorin Calcium, Fluorouracil, and Oxaliplatin in Treating Patients With Advanced Metastatic Colorectal Cancer

NCT02041481

COMPLETED NA

Survivorship Care Planning in Improving Quality of Life in Survivors of Ovarian Cancer

NCT02082470

COMPLETED NA

Computed Tomography and Biomarker Analysis in Diagnosing Coronary Artery Disease in Asymptomatic Patients Who Have Undergone Stem Cell Transplant

NCT02077218

COMPLETED Phase 1

Vaccine Therapy in Healthy Volunteers With or Without Previous Exposure to Cytomegalovirus

NCT01941056

COMPLETED NA

Fluorine F 18 Sodium Fluoride PET/CT and Whole Body and Axial MRI in Finding Metastases in Patients With Recurrent Prostate Cancer

NCT01967862

COMPLETED NA

Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung Cancers

NCT01846520

TERMINATED Phase 1

Dasatinib, Cytarabine, and Idarubicin in Treating Patients With High-Risk Acute Myeloid Leukemia

NCT01876953

COMPLETED NA

Psycho-Educational Program in Increasing Knowledge and Satisfaction and Decreasing Distress in Younger Patients With Cancer Receiving Treatment

NCT01817335

TERMINATED

Optimization of Novel DCE-MRI Imaging Sequences for Cancer Therapy Monitoring

NCT01752231

COMPLETED Phase 1

PI3K Inhibitor BKM120, Carboplatin, and Pemetrexed Disodium in Treating Patients With Stage IV Non-Small Cell Lung Cancer

NCT01723800

COMPLETED Phase 2

Sipuleucel-T With or Without Radiation Therapy in Treating Patients With Hormone-Resistant Metastatic Prostate Cancer

NCT01807065

COMPLETED NA

Quality of Life in Caregivers of Hospitalized Older Patients With Cancer

NCT01866969

COMPLETED NA

Feasibility of Intraoperative Optical Imaging and Spectroscopy in Brain Tumors

NCT01627535

COMPLETED NA

Survivorship Care Planning in Patients With Colorectal or Non-Small Cell Lung Cancer

NCT01741636

COMPLETED NA

Validation of an RLIP76 Assay in Humans

NCT01824017

COMPLETED Phase 1

Radiolabeled Monoclonal Antibody Therapy and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With Primary Refractory or Relapsed Hodgkin Lymphoma

NCT01476839

COMPLETED Phase 2

Pilot Trial of CRLX101 in Treatment of Patients With Advanced or Metastatic Stomach, Gastroesophageal, or Esophageal Cancer That Cannot be Removed by Surgery

NCT01612546

COMPLETED Phase 1

Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant

NCT01588015

TERMINATED NA

Biomarkers in Tissue Samples From Patients With Newly Diagnosed Breast Cancer Treated With Zoledronic Acid

NCT01409811

COMPLETED Phase 3

Robotic Assisted Laparoscopic Prostatectomy With or Without Pelvic Drain Placement in Reducing Adverse Events After Surgery in Patients With Prostate Cancer

NCT01613651

TERMINATED NA

Feasibility of a Supportive Education Program for Latina Breast Cancer Survivors

NCT01628887

COMPLETED NA

Palliative Care Intervention in Patients With Solid Tumors Participating in Phase I Clinical Trials

NCT01612598

TERMINATED NA

Minimally Invasive Surgery in Treating Patients With Spinal Tumors

NCT01308489

COMPLETED Phase 1

Everolimus and Combination Chemotherapy in Treating Patients With Metastatic Stomach or Esophageal Cancer

NCT01231399

COMPLETED Phase 2

Axitinib Before Surgery in Treating Patients With High-Risk Prostate Cancer

NCT01385059

COMPLETED Phase 2

Brentuximab Vedotin Before Autologous Stem Cell Transplant in Treating Patients With Hodgkin Lymphoma

NCT01393717

COMPLETED Phase 1

Fluorescence Imaging in Finding Tumors in Patients With Kidney Tumors

NCT01281488

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What is open in the City of Hope Medical Center pipeline

167 recruiting of 582 indexed (29% open); 217 completed (37%).

Phase mix: 9 late (III/IV) vs 382 early (I/II) (early-phase heavy).

Top condition: Acute Myeloid Leukemia (22 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

City of Hope Medical Center: open-pipeline peers nationwide

Peers matched on 582 registered trials and 29% open enrollment, not the therapeutic-area sidebar.

City of Hope Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%10%20%30%40% Total trials Recruiting share City of Hope Medical CenterBayerJanssen Research & DevelopmentChildren's Hospital Medical Center, CincinnatiNational Institute of Neurological Disorders and Stroke (NINDS)Methodist Health System89bioAlabama Physical Therapy & AcupunctureAlloSource
City of Hope Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

City of Hope Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 582 trials (± recruiting share)

Sponsors near 29% open enrollment (± trial volume)

What to do with this City of Hope Medical Center page

582 registered trials is a research-attention snapshot, not an endorsement of City of Hope Medical Center or any single study.

  • 167 of City of Hope Medical Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Acute Myeloid Leukemia is the condition City of Hope Medical Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Acute Myeloid Leukemia trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. City of Hope Medical Center pipeline card: 582 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.