City of Hope Medical Center

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, City of Hope Medical Center sits in the top decile of US sponsors by registered trial count (#59 of 15,742 sponsors by registered trial count).

582 total trials 167 currently recruiting 217 completed early-phase tilt top decile by trial count

City of Hope Medical Center: 582 sponsored US clinical trials, 167 recruiting.

City of Hope Medical Center sponsors 582 registered US clinical trials on ClinicalTrials.gov, 167 of them currently recruiting, and 217 completed. 9 of these trials are in Phase 3-4 (later-stage) and 382 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Acute Myeloid Leukemia, with 22 trials.

Top-decile sponsor footprint

City of Hope Medical Center ranks in the top decile of sponsors by registered trial count (#59 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 61/100

217 of 245 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

582 total, page 12 of 12

COMPLETED Phase 2

Cyclophosphamide With or Without Celecoxib in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer

NCT00538031

COMPLETED Phase 2

Tamoxifen, Carboplatin, and Topotecan in Treating Patients With CNS Metastases or Recurrent Brain or Spinal Cord Tumors

NCT00541138

COMPLETED Phase 2

Imatinib Mesylate in Treating Patients With Recurrent Ewing's Family of Tumors or Desmoplastic Small Round-Cell Tumor

NCT00062205

COMPLETED Phase 1

R115777 in Treating Patients With Advanced Solid Tumors

NCT00025454

TERMINATED

Nipple Secretion Samples in Detecting Breast Cancer in Patients and Healthy Participants Undergoing Breast Cancer Screening, Breast Diagnostic Studies, or Treatment for Benign Breast Disease

NCT00813878

COMPLETED Phase 2

CCI-779 in Treating Patients With Metastatic Melanoma

NCT00022464

COMPLETED Phase 1

UCN-01 and Cisplatin in Treating Patients With Advanced or Metastatic Solid Tumors

NCT00006464

COMPLETED Phase 2

Chloroquinoxaline Sulfonamide in Treating Patients With Small Cell Lung Cancer

NCT00008372

COMPLETED Phase 2

SU5416 and Interferon Alfa-2b in Treating Patients With Unresectable or Metastatic Kidney Cancer

NCT00006384

COMPLETED Phase 1

SU5416 and Paclitaxel in Treating Patients With Advanced Cancer

NCT00006257

COMPLETED Phase 2

Trastuzumab and Docetaxel in Treating Patients Who Have Metastatic Prostate Cancer That Is Refractory to Hormone Therapy

NCT00005857

COMPLETED Phase 1

Oxaliplatin Plus Capecitabine in Treating Patients With Metastatic or Recurrent Solid Tumor

NCT00005839

COMPLETED Phase 1

Docetaxel and Oxaliplatin in Treating Patients With Metastatic or Recurrent Solid Tumor

NCT00004243

COMPLETED Phase 1

Tirapazamine, Carboplatin, and Paclitaxel in Treating Patients With Advanced Malignant Solid Tumors

NCT00005078

COMPLETED Phase 1

Oxaliplatin in Treating Patients With Advanced Cancer Plus Liver Dysfunction

NCT00005077

COMPLETED Phase 1

Oxaliplatin and Gemcitabine in Treating Patients With Advanced Cancer

NCT00004220

COMPLETED Phase 1

Combination Chemotherapy, Amifostine, and Peripheral Stem Cell Transplantation in Treating Patients With Stage II, Stage III, or Stage IV Breast Cancer

NCT00003927

COMPLETED Phase 2

Combination Chemotherapy in Treating Patients With High-Risk Breast Cancer

NCT00004092

COMPLETED Phase 2

Combination Chemo, Peripheral Stem Cell Transplant, Biological Therapy, Pamidronate and Thalidomide for Multiple Myeloma

NCT00004088

COMPLETED Phase 1

5-Fluoro-2'-Deoxcyctidine and Tetrahydrouridine to Treat Patients With Advanced Cancer

NCT00359606

COMPLETED Phase 2

Ganciclovir by Infusion and by Mouth in Treating Patients With Cytomegalovirus After Donor Bone Marrow Transplant

NCT00530218

COMPLETED Phase 2

Combination Chemotherapy With or Without Total-Body Irradiation Followed By Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma

NCT00559104

COMPLETED Phase 1

Cytomegalovirus Vaccine in Healthy Participants

NCT00712634

COMPLETED Phase 2

Chemotherapy and Stem Cell Transplantation in Treating Patients With Stage IIIB Breast Cancer

NCT00003042

COMPLETED Phase 1

Vinorelbine in Treating Patients With Advanced Solid Tumors That Have Not Responded to Treatment and Liver Dysfunction

NCT00540982

COMPLETED Phase 2

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer

NCT00002931

COMPLETED Phase 1

Docetaxel in Treating Patients With Solid Tumors and Abnormal Liver Function

NCT00002901

COMPLETED Phase 2

Paclitaxel With or Without PSC 833 in Treating Patients With Metastatic Breast Cancer

NCT00002937

COMPLETED Phase 1

High-Dose Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Advanced Cancer

NCT00002854

COMPLETED Phase 2

Liver Resection and Floxuridine Plus Fluorouracil and Leucovorin in Treating Patients With Liver Metastases From Colorectal Cancer

NCT00002842

COMPLETED Phase 2

Idarubicin and High-Dose Cytarabine in Treating Patients With Acute Myeloid Leukemia

NCT00528398

COMPLETED Phase 2

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Sarcoma

NCT00002601

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What is open in the City of Hope Medical Center pipeline

167 recruiting of 582 indexed (29% open); 217 completed (37%).

Phase mix: 9 late (III/IV) vs 382 early (I/II) (early-phase heavy).

Top condition: Acute Myeloid Leukemia (22 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

City of Hope Medical Center: open-pipeline peers nationwide

Peers matched on 582 registered trials and 29% open enrollment, not the therapeutic-area sidebar.

City of Hope Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%10%20%30%40% Total trials Recruiting share City of Hope Medical CenterBayerJanssen Research & DevelopmentChildren's Hospital Medical Center, CincinnatiNational Institute of Neurological Disorders and Stroke (NINDS)Methodist Health System89bioAlabama Physical Therapy & AcupunctureAlloSource
City of Hope Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

City of Hope Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 582 trials (± recruiting share)

Sponsors near 29% open enrollment (± trial volume)

What to do with this City of Hope Medical Center page

582 registered trials is a research-attention snapshot, not an endorsement of City of Hope Medical Center or any single study.

  • 167 of City of Hope Medical Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Acute Myeloid Leukemia is the condition City of Hope Medical Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Acute Myeloid Leukemia trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. City of Hope Medical Center pipeline card: 582 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.