Baxalta now part of Shire

74 total trials 1 currently recruiting 58 completed

Baxalta now part of Shire sponsors 74 registered US clinical trials on ClinicalTrials.gov, 1 of them currently recruiting, and 58 completed. 34 of these trials are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hemophilia A, with 4 trials.

Trial Pipeline

74 total, page 1 of 2

RECRUITING Phase 3

A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD)

NCT02932618

ACTIVE NOT RECRUITING

A Long-term Study of ADYNOVI/ADYNOVATE in Participants With Haemophilia A

NCT04158934

ACTIVE NOT RECRUITING Phase 1

Open-Label Single Ascending Dose of Adeno-associated Virus Serotype 8 Factor IX Gene Therapy in Adults With Hemophilia B

NCT01687608

COMPLETED Phase 1

A Study to Assess the Tolerability, Safety, and Pharmacokinetics of Subcutaneous Immune Globulin Infusion 10% (Human) With Recombinant Human Hyaluronidase (HYQVIA/HyQvia) With Ramp-up and No Ramp-up Dosing in Healthy Adult Participants

NCT04578535

COMPLETED Phase 3

A Study of Recombinant Von Willebrand Factor (rVWF) in Pediatric and Adult Participants With Severe Von Willebrand Disease (VWD)

NCT03879135

COMPLETED

Prospective Psychometric Evaluation Study of a Patient-reported Outcomes (PRO) Instrument for Congenital Thrombotic Thrombocytopenic Purpura (cTTP, Upshaw-Schulman Syndrome [USS], Hereditary Thrombotic Thrombocytopenic Purpura [hTTP]

NCT03519672

COMPLETED Phase 1

A Study of BAX 888 in Male Adults With Severe Hemophilia A

NCT03370172

COMPLETED Phase 3

A Study of BAX 930 in Children, Teenagers, and Adults Born With Thrombotic Thrombocytopenic Purpura (TTP)

NCT03393975

COMPLETED Phase 3

Efficacy, Safety, Tolerability, Immunogenicity and Pharmacokinetic Evaluation of HYQVIA in Pediatric PIDD Subjects

NCT03277313

COMPLETED

Global Epidemiologic Study of Preexisting Immunity to AAV in Adults With Severe Hemophilia

NCT03185897

TERMINATED Phase 2

A Phase 2/3 Study of GLASSIA for the Treatment of Acute GvHD

NCT02956122

COMPLETED

Non-Interventional Study to Capture the Patient Experience on Gene Therapy for Hemophilia Within the AskBio009-101 Study Through Patient and Investigator Interviews

NCT03054389

TERMINATED Phase 3

BAX 802 in CHA With Inhibitors

NCT02895945

COMPLETED

Prospective and Retrospective, Non-interventional Study to Evaluate the Safety and Effectiveness of Obizur in Real-life Practice

NCT03199794

COMPLETED Phase 3

Long-Term Tolerability and Safety of HYQVIA/HyQvia in CIDP

NCT02955355

TERMINATED Phase 3

Stage 1 Study of ARALAST NP and GLASSIA in A1PI Deficiency

NCT02722304

COMPLETED

GAS-Hem Feasibility Study

NCT02674997

COMPLETED Phase 3

GLASSIA Safety, Immunogenicity, and Bronchoalveolar Lavage Study

NCT02525861

COMPLETED

Post-Marketing Non-Interventional Safety Evaluation of Obizur in the Treatment of Bleeding Episodes for Patients With Acquired Hemophilia A

NCT02610127

COMPLETED Phase 3

A Study of HyQvia and Gammagard Liquid (Kiovig) in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

NCT02549170

COMPLETED

Pregnancy Registry to Collect Long-Term Safety Data From Women Treated With HyQvia

NCT02556775

COMPLETED Phase 3

BAX 855 PK-guided Dosing

NCT02585960

COMPLETED

Non-Interventional Post-Marketing Safety Study on the Long-Term Safety of HYQVIA (Global)

NCT02593188

COMPLETED Phase 3

A Study of PEGylated Recombinant Factor VIII (BAX855) in Previously Untreated Young Children With Severe Hemophilia A

NCT02615691

TERMINATED Phase 1

Phase 1/2a Two-Arm Dose-Escalation Study of BAX69 in Subjects With Malignant Ascites of Ovarian Cancer

NCT02540356

TERMINATED Phase 2

Phase 2a Study of BAX69 and 5-FU/Leucovorin or Panitumumab Versus Standard of Care in Subjects With Metastatic Colorectal Cancer

NCT02448810

COMPLETED Phase 3

Recombinant Von Willebrand Factor in Subjects With Severe Von Willebrand Disease Undergoing Surgery

NCT02283268

COMPLETED Phase 3

BAX 855 Pediatric Study

NCT02210091

COMPLETED Phase 1

Phase 1 Dose Escalation, Single Dose Study to Assess Safety and Pharmacokinetics of BAX930 in Hereditary Thrombotic Thrombocytopenic Purpura (TTP)

NCT02216084

COMPLETED

Study of Prophylaxis, ACtivity and Effectiveness (SPACE) in Hemophilia Patients Currently Treated With ADVATE or RIXUBIS

NCT02190149

COMPLETED Phase 3

Phase 3 Efficacy and Safety Study of BAX 855 in Severe Hemophilia A Patients Undergoing Surgical Procedures

NCT01913405

COMPLETED Phase 3

BAX 855 Continuation

NCT01945593

COMPLETED Phase 3

Recombinant Factor VIIa BI (rFVIIa BI) Treatment of Acute Bleeding Episodes Per an On-demand Regimen

NCT01757405

COMPLETED Phase 2

Study Investigating a PEGylated Recombinant Factor VIII (BAX 855) for Hemophilia A (PROLONG-ATE Study)

NCT01736475

COMPLETED Phase 2

Phase 2/3 Study of IGSC, 20% in PIDD

NCT01218438

TERMINATED Phase 3

Long-Term Study of IGIV, 10% in Alzheimer´s Disease

NCT01736579

COMPLETED Phase 4

GLASSIA Infusion Rate Study

NCT01651351

COMPLETED Phase 1

Phase 1 Study of Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody in Solid Tumors

NCT01765790

COMPLETED Phase 1

A Single Dose Study of the Safety, Blood Levels and Biological Effects of Aes-103 Compared to Placebo in Subjects With Stable Sickle Cell Disease

NCT01597401

TERMINATED Phase 3

Phase 3 IGIV, 10% in Alzheimer´s Disease

NCT01524887

COMPLETED Phase 2

Tolerability and Safety of IGI, 10% With rHuPH20 in PIDD

NCT01485796

TERMINATED Phase 1

Safety Study of Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody in Lupus Nephritis

NCT01541670

COMPLETED Phase 3

Pharmacokinetics, Safety and Efficacy of Recombinant Von Willebrand Factor (rVWF) in the Treatment of Bleeding Episodes in Von Willebrand Disease (VWD)

NCT01410227

TERMINATED NA

Osteoporosis and MRI Study in Hemophilia

NCT01460147

TERMINATED Phase 3

Study of Modified Recombinant Factor VIII (OBI-1) in Subjects With Congenital Hemophilia A

NCT01434511

TERMINATED Phase 3

Early Prophylaxis Immunologic Challenge (EPIC) Study

NCT01376700

COMPLETED Phase 2

Study of Modified Recombinant Factor VIII (OBI-1) in Subjects With Acquired Hemophilia A

NCT01178294

COMPLETED Phase 3

Tolerability and Safety of Immune Globulin Subcutaneous Solution (IGSC) and rHuPH20 in PID

NCT01175213

COMPLETED

Ceprotin Treatment Registry

NCT01127529

COMPLETED Phase 3

Efficacy and Safety Study of Prophylactic Versus On-Demand Treatment With Feiba NF in Subjects With Hemophilia A or B and a High Titer Inhibitor

NCT00851721

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Phase Distribution

PhaseTrial count
Phase 1 15
Phase 2 11
Phase 3 29
Phase 4 5

What the Pipeline for Baxalta now part of Shire Shows

According to the ClinicalTrials.gov registry, Baxalta now part of Shire is linked to 74 US clinical trials across every stage of research activity. Of those, 1 studies are currently recruiting, about 1% of the sponsor's indexed portfolio, and 58 are already marked complete, representing roughly 78% of the total.

The phase mix for Baxalta now part of Shire reports 34 late-stage studies (Phase 3 and Phase 4 combined) and 26 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Baxalta now part of Shire is Hemophilia A with 4 linked trials, and 5 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.