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NCT01175213 · ClinicalTrials.gov registry record · Phase 3

Tolerability and Safety of Immune Globulin Subcutaneous Solution (IGSC) and rHuPH20 in PID

A Phase 3 study, sponsored by Baxalta now part of Shire.

Completed
Registry status
Phase 3
Development phase
66
Enrollment target

NCT01175213 is a Phase 3 study that has completed, run by Baxalta now part of Shire. The registered enrollment target is 66 participants.

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The verdict

NCT01175213, a Phase 3 study, has completed, sponsored by Baxalta now part of Shire.

COMPLETED
Registry status
Phase 3
Development phase
66 participants
Enrollment target

Study Summary

The original purpose of the study is to assess the long-term safety, tolerability, and practicability of the subcutaneous (SC) treatment with Immune Globulin Subcutaneous Solution (IGSC), 10% facilitated with recombinant human hyaluronidase (rHuPH20) in participants with Primary Immunodeficiency Diseases (PID) who have completed Baxter Clinical Study Protocol No. 160603. Following a discussion with the FDA, all participants still active in the study stopped treatment with rHuPH20 to assure safety of the participants participating in the study and went into a safety follow-up. During this safety follow-up period, participants underwent either intravenous (IV) or SC treatment with IGSC, 10%. The IV or SC administration route was at the discretion of the participant and the investigator.

Interventions

  • BIOLOGICAL SC treatment with IGSC, 10% with rHuPH20 followed by SC/IGSC, 10% only (safety)
  • BIOLOGICAL SC treatment with IGSC, 10% with rHuPH20 followed by IV/IGSC, 10% only (safety)
  • BIOLOGICAL IV treatment with IGSC, 10%

Trial Details

FieldValue
Enrollment Target 66 participants
Start Date 2010-07-28
Est. Completion 2013-08-06
Phase Phase 3

Sponsor

Baxalta now part of Shire

74 total trials

What the Registry Record Tells You About NCT01175213

The ClinicalTrials.gov registry entry for NCT01175213 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 66 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Baxalta now part of Shire, which has 74 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which SC treatment with IGSC, 10% with rHuPH20 followed by SC/IGSC, 10% only (safety) is the first listed.

NCT01175213 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01175213 about?

NCT01175213 is a clinical study titled "Tolerability and Safety of Immune Globulin Subcutaneous Solution (IGSC) and rHuPH20 in PID". The original purpose of the study is to assess the long-term safety, tolerability, and practicability of the subcutaneous (SC) treatment with Immune Globulin Subcutaneous Solution (IGSC), 10% facilitated with recombinant human hyaluronidase (rHuPH20) in participants with Primary Immunodeficiency Dis...

What is the current status of trial NCT01175213?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 66 participants. The study started on 2010-07-28. Estimated completion is 2013-08-06.

What interventions are being tested in trial NCT01175213?

The interventions under investigation include: SC treatment with IGSC, 10% with rHuPH20 followed by SC/IGSC, 10% only (safety) (BIOLOGICAL), SC treatment with IGSC, 10% with rHuPH20 followed by IV/IGSC, 10% only (safety) (BIOLOGICAL), IV treatment with IGSC, 10% (BIOLOGICAL).

Who is sponsoring clinical trial NCT01175213?

This trial is sponsored by Baxalta now part of Shire, which has 74 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.