Baxalta now part of Shire
Baxalta now part of Shire sponsors 74 registered US clinical trials on ClinicalTrials.gov, 1 of them currently recruiting, and 58 completed. 34 of these trials are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hemophilia A, with 4 trials.
Trial Pipeline
74 total, page 1 of 2
A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD)
NCT02932618
A Long-term Study of ADYNOVI/ADYNOVATE in Participants With Haemophilia A
NCT04158934
Open-Label Single Ascending Dose of Adeno-associated Virus Serotype 8 Factor IX Gene Therapy in Adults With Hemophilia B
NCT01687608
A Study to Assess the Tolerability, Safety, and Pharmacokinetics of Subcutaneous Immune Globulin Infusion 10% (Human) With Recombinant Human Hyaluronidase (HYQVIA/HyQvia) With Ramp-up and No Ramp-up Dosing in Healthy Adult Participants
NCT04578535
A Study of Recombinant Von Willebrand Factor (rVWF) in Pediatric and Adult Participants With Severe Von Willebrand Disease (VWD)
NCT03879135
Prospective Psychometric Evaluation Study of a Patient-reported Outcomes (PRO) Instrument for Congenital Thrombotic Thrombocytopenic Purpura (cTTP, Upshaw-Schulman Syndrome [USS], Hereditary Thrombotic Thrombocytopenic Purpura [hTTP]
NCT03519672
A Study of BAX 888 in Male Adults With Severe Hemophilia A
NCT03370172
A Study of BAX 930 in Children, Teenagers, and Adults Born With Thrombotic Thrombocytopenic Purpura (TTP)
NCT03393975
Efficacy, Safety, Tolerability, Immunogenicity and Pharmacokinetic Evaluation of HYQVIA in Pediatric PIDD Subjects
NCT03277313
Global Epidemiologic Study of Preexisting Immunity to AAV in Adults With Severe Hemophilia
NCT03185897
A Phase 2/3 Study of GLASSIA for the Treatment of Acute GvHD
NCT02956122
Non-Interventional Study to Capture the Patient Experience on Gene Therapy for Hemophilia Within the AskBio009-101 Study Through Patient and Investigator Interviews
NCT03054389
BAX 802 in CHA With Inhibitors
NCT02895945
Prospective and Retrospective, Non-interventional Study to Evaluate the Safety and Effectiveness of Obizur in Real-life Practice
NCT03199794
Long-Term Tolerability and Safety of HYQVIA/HyQvia in CIDP
NCT02955355
Stage 1 Study of ARALAST NP and GLASSIA in A1PI Deficiency
NCT02722304
GAS-Hem Feasibility Study
NCT02674997
GLASSIA Safety, Immunogenicity, and Bronchoalveolar Lavage Study
NCT02525861
Post-Marketing Non-Interventional Safety Evaluation of Obizur in the Treatment of Bleeding Episodes for Patients With Acquired Hemophilia A
NCT02610127
A Study of HyQvia and Gammagard Liquid (Kiovig) in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
NCT02549170
Pregnancy Registry to Collect Long-Term Safety Data From Women Treated With HyQvia
NCT02556775
BAX 855 PK-guided Dosing
NCT02585960
Non-Interventional Post-Marketing Safety Study on the Long-Term Safety of HYQVIA (Global)
NCT02593188
A Study of PEGylated Recombinant Factor VIII (BAX855) in Previously Untreated Young Children With Severe Hemophilia A
NCT02615691
Phase 1/2a Two-Arm Dose-Escalation Study of BAX69 in Subjects With Malignant Ascites of Ovarian Cancer
NCT02540356
Phase 2a Study of BAX69 and 5-FU/Leucovorin or Panitumumab Versus Standard of Care in Subjects With Metastatic Colorectal Cancer
NCT02448810
Recombinant Von Willebrand Factor in Subjects With Severe Von Willebrand Disease Undergoing Surgery
NCT02283268
BAX 855 Pediatric Study
NCT02210091
Phase 1 Dose Escalation, Single Dose Study to Assess Safety and Pharmacokinetics of BAX930 in Hereditary Thrombotic Thrombocytopenic Purpura (TTP)
NCT02216084
Study of Prophylaxis, ACtivity and Effectiveness (SPACE) in Hemophilia Patients Currently Treated With ADVATE or RIXUBIS
NCT02190149
Phase 3 Efficacy and Safety Study of BAX 855 in Severe Hemophilia A Patients Undergoing Surgical Procedures
NCT01913405
BAX 855 Continuation
NCT01945593
Recombinant Factor VIIa BI (rFVIIa BI) Treatment of Acute Bleeding Episodes Per an On-demand Regimen
NCT01757405
Study Investigating a PEGylated Recombinant Factor VIII (BAX 855) for Hemophilia A (PROLONG-ATE Study)
NCT01736475
Phase 2/3 Study of IGSC, 20% in PIDD
NCT01218438
Long-Term Study of IGIV, 10% in Alzheimer´s Disease
NCT01736579
GLASSIA Infusion Rate Study
NCT01651351
Phase 1 Study of Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody in Solid Tumors
NCT01765790
A Single Dose Study of the Safety, Blood Levels and Biological Effects of Aes-103 Compared to Placebo in Subjects With Stable Sickle Cell Disease
NCT01597401
Phase 3 IGIV, 10% in Alzheimer´s Disease
NCT01524887
Tolerability and Safety of IGI, 10% With rHuPH20 in PIDD
NCT01485796
Safety Study of Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody in Lupus Nephritis
NCT01541670
Pharmacokinetics, Safety and Efficacy of Recombinant Von Willebrand Factor (rVWF) in the Treatment of Bleeding Episodes in Von Willebrand Disease (VWD)
NCT01410227
Osteoporosis and MRI Study in Hemophilia
NCT01460147
Study of Modified Recombinant Factor VIII (OBI-1) in Subjects With Congenital Hemophilia A
NCT01434511
Early Prophylaxis Immunologic Challenge (EPIC) Study
NCT01376700
Study of Modified Recombinant Factor VIII (OBI-1) in Subjects With Acquired Hemophilia A
NCT01178294
Tolerability and Safety of Immune Globulin Subcutaneous Solution (IGSC) and rHuPH20 in PID
NCT01175213
Ceprotin Treatment Registry
NCT01127529
Efficacy and Safety Study of Prophylactic Versus On-Demand Treatment With Feiba NF in Subjects With Hemophilia A or B and a High Titer Inhibitor
NCT00851721
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 15 |
| Phase 2 | 11 |
| Phase 3 | 29 |
| Phase 4 | 5 |
What the Pipeline for Baxalta now part of Shire Shows
According to the ClinicalTrials.gov registry, Baxalta now part of Shire is linked to 74 US clinical trials across every stage of research activity. Of those, 1 studies are currently recruiting, about 1% of the sponsor's indexed portfolio, and 58 are already marked complete, representing roughly 78% of the total.
The phase mix for Baxalta now part of Shire reports 34 late-stage studies (Phase 3 and Phase 4 combined) and 26 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Baxalta now part of Shire is Hemophilia A with 4 linked trials, and 5 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.