Baxalta now part of Shire

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, Baxalta now part of Shire sits in the top decile of US sponsors by registered trial count (#294 of 15,742 sponsors by registered trial count).

74 total trials 1 currently recruiting 58 completed top decile by trial count

Baxalta now part of Shire: 74 sponsored US clinical trials, 1 recruiting.

Baxalta now part of Shire sponsors 74 registered US clinical trials on ClinicalTrials.gov, 1 of them currently recruiting, and 58 completed. 34 of these trials are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hemophilia A, with 4 trials.

Top-decile sponsor footprint

Baxalta now part of Shire ranks in the top decile of sponsors by registered trial count (#294 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 44/100

58 of 71 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

74 total, page 2 of 2

COMPLETED Phase 3

A Phase 3 Study Evaluating Safety and Effectiveness of Immune Globulin Intravenous (IGIV 10%) for the Treatment of Mild-to-Moderate Alzheimer´s Disease

NCT00818662

COMPLETED Phase 3

Gammagard Liquid and rHuPH20 in PID

NCT00814320

COMPLETED Phase 1

Pharmacokinetic, Safety and Tolerability Study of Recombinant Von Willebrand Factor / Recombinant Factor VIII Complex in Type 3 Von Willebrand Disease

NCT00816660

COMPLETED Phase 3

Study of the Effectiveness of Intravenous Immune Globulin (10%) for the Treatment of Multifocal Motor Neuropathy

NCT00666263

COMPLETED Phase 1

Pharmacokinetic Study of ADVATE Reconstituted in 2 mL Sterile Water for Injection

NCT00952822

COMPLETED Phase 1

A Study of Plasma-Derived Human Butyrylcholinesterase Administered Intramuscularly

NCT00333528

COMPLETED Phase 2

Comparison of Intravenous and Subcutaneous Administration of IGIV, 10% in Primary Immunodeficiency (PID) Subjects

NCT00546871

COMPLETED Phase 1

Pharmacokinetic (PK) and Safety Study of Plasma-derived Human Butyrylcholinesterase Administered Intravenously

NCT00333515

COMPLETED Phase 1

Study to Determine the Dose of Recombinant Human Hyaluronidase Needed to Infuse a Full Dose of IGIV Subcutaneously

NCT00782106

TERMINATED Phase 4

Aralast alpha1-proteinase Inhibitor Surveillance Study

NCT00313144

COMPLETED Phase 4

Phase 3/4 Study of a Recombinant Protein-Free Factor VIII (rAHF-PFM): Comparison of Continuous Infusion Versus Intermittent Bolus Infusion in Hemophilia A Subjects Undergoing Major Orthopedic Surgery

NCT00357656

COMPLETED Phase 4

Dose-Response Study of Recombinant Factor VIII Manufactured Protein-Free (rAHF-PFM) in Patients With Hemophilia A

NCT00289536

COMPLETED Phase 4

Prophylaxis Study of Recombinant Factor VIII Manufactured Protein-Free (rAHF-PFM) in Patients With Hemophilia A

NCT00243386

COMPLETED

Retrospective Study to Capture Dosing and Treatment Outcome Data in Participants With Severe Congenital Protein C Deficiency Who Were Treated With Protein C Concentrate Under an Emergency Use IND

NCT00161720

COMPLETED

ADVATE Post Authorization Safety Surveillance

NCT00214734

COMPLETED Phase 3

Efficacy and Safety Study of a Recombinant Protein-Free Manufactured Factor VIII (rAHF-PFM) in Previously Untreated Hemophilia A Patients

NCT00157157

COMPLETED Phase 1

Study of the Effect of Aerosolized, Recombinant Alpha 1-Antitrypsin on Epithelial Lining Fluid Analytes in Subjects With Alpha 1-Antitrypsin Deficiency

NCT00157092

COMPLETED Phase 2

Efficacy and Safety Study of Protein C Concentrate in Subjects With Severe Congenital Protein C Deficiency

NCT00157118

COMPLETED Phase 1

Safety Study of an Aerosolized, Recombinant Alpha 1-Antitrypsin in Subjects With Alpha 1-Antitrypsin Deficiency

NCT00161707

COMPLETED Phase 3

Safety and Efficacy Study of a 10% Intravenous Immune Globulin Solution in Subjects With Primary Immunodeficiency Disorders

NCT00157079

COMPLETED Phase 2

Study of Pharmacokinetics, Efficacy, and Safety of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Pediatric Patients With Hemophilia A

NCT00157040

COMPLETED Phase 2

Study of Pharmacokinetics, Efficacy and Safety of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Hemophilia A Patients - A Continuation of Clinical Study 069901

NCT00157053

COMPLETED Phase 2

Safety and Efficacy Study of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Hemophilia A Patients Undergoing Surgery

NCT00157105

TERMINATED Phase 3

Prevention of Graft-Versus-Host Disease in Patients With Advanced Leukemia or Lymphoma Who Are Eligible for Peripheral Stem Cell Transplantation

NCT00003056

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Phase Distribution

PhaseTrial count
Phase 1 15
Phase 2 11
Phase 3 29
Phase 4 5

What is open in the Baxalta now part of Shire pipeline

1 recruiting of 74 indexed (1% open); 58 completed (78%).

Phase mix: 34 late (III/IV) vs 26 early (I/II) (balanced across stages).

Top condition: Hemophilia A (4 trials), 5 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Baxalta now part of Shire: open-pipeline peers nationwide

Peers matched on 74 registered trials and 1% open enrollment, not the therapeutic-area sidebar.

Baxalta now part of Shire sits below the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 50100150200 0%10%20%30%40% Total trials Recruiting share Baxalta now part of ShireC. R. BardECOG-ACRIN Cancer Research GroupHartford HospitalInova Health Care ServicesAstellas PharmaUniversity of New MexicoAbbott NutritionPower Life Sciences
Baxalta now part of Shire sits below the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Baxalta now part of Shire sits below the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 74 trials (± recruiting share)

Sponsors near 1% open enrollment (± trial volume)

What to do with this Baxalta now part of Shire page

74 registered trials is a research-attention snapshot, not an endorsement of Baxalta now part of Shire or any single study.

  • 1 of Baxalta now part of Shire's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Hemophilia A is the condition Baxalta now part of Shire studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Hemophilia A trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Baxalta now part of Shire pipeline card: 74 registered trials from official public datasets.Report a data error.