Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Wrinkles: early-phase trial registry
A small indexed set (8 trials) with no open enrollment listed right now.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · none currently recruiting · #2,176 of 28,707 conditions by registered trial count
Wrinkles: 8 US clinical trials tracked, none currently recruiting.
Wrinkles is the subject of 8 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 1 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Northwestern University, running 2 of these trials.
Enrollment posture brief
Registry condition wrinkles
OPEN 0 | RECR 0% | LATE 1 | EARLY 2 | RANK #2176 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia (0% recruiting · 12 trials)
Wrinkles has no open enrollment in this registry pull (8 archived studies). Peers show how other volume-matched labels compare on open share. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Wrinkles on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Wrinkles is recruiting below its size-band peers.
0 of 8 indexed trials (0%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
One sponsor concentrates Wrinkles research.
Northwestern University accounts for 2 of 8 trials (25%). 6 distinct sponsors appear on at least one study for this condition label.
-
Most Wrinkles trials plan to enrol fewer than 100 people.
Median target enrolment is 40 among the 8 trials that report a genuine target (sentinel values excluded). 7 of those (87.5%) plan for fewer than 100 participants.
-
Wrinkles research is mostly interventional.
7 interventional and 1 observational studies make up this index (87.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Indexed trials (enrollment closed)
8 total, page 1 of 1
Fractional Laser vs. Ultrasound for Periorbital Wrinkles
Northwestern University
NCT01529983
A Pilot Study Testing Onabotulinum Toxin A Versus Incobotulinum Toxin A Injections for Facial Wrinkles
Northwestern University
NCT02019004
Study of BOTOX and JUVEDERM for Treatment of Moderate to Severe Facial Wrinkles and Folds
AboutSkin Dermatology and DermSurgery, PC
NCT01269801
A Clinical Study to Evaluate Efficacy and Safety of a Cosmetic Product in the Treatment of Facial Lines
Revision Skincare
NCT04545970
Prospective Study Evaluating the Treatment of Hyperdynamic Forehead Wrinkles
Pacira Pharmaceuticals
NCT01984619
The Effect of Topical Almond Oil vs. Topical Retinol on The Appearance of Facial Wrinkles
University of California, Davis
NCT05011461
Pilot Study of Triphala and Rubia Cordifolia on Gut Microbiome and Skin
University of California, Davis
NCT03477825
Evaluating the Safety and Efficacy of the Pico Laser With a Specialized Lens Array for the Treatment of Wrinkles
Cynosure
NCT02091102
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Wrinkles records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Wrinkles trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Wrinkles page
8 registered trials, 0 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- No Wrinkles trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
- Northwestern University sponsors the most Wrinkles trials on record, review their full trial history before evaluating a specific study. See Northwestern University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Wrinkles condition card totals 8 registered trials; most-linked intervention Cryotherapy for the utilization of wrinkle reduction (iovera); top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.