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ClinicalTrials.gov 5 recruiting now later-stage tilt small index

Venous Ulcer: later-stage trial registry

5 of 12 indexed Venous Ulcer trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 5 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Venous Ulcer: 12 US clinical trials tracked, 5 recruiting.

Venous Ulcer is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Organogenesis, running 3 of these trials.

Enrollment posture brief

Registry condition venous-ulcer

OPEN 5 | RECR 42% | LATE 4 | EARLY 1 | RANK #1429 | SPON 3

Nearest open-share peer: Adiposity (42% recruiting · 12 trials)

Venous Ulcer (this)42%Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Venous Ulcer

Venous Ulcer lists 5 open slots (42% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Venous Ulcer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Venous Ulcer is recruiting below its size-band peers.

    5 of 12 indexed trials (41.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Venous Ulcer research.

    Organogenesis accounts for 3 of 12 trials (25%). 8 distinct sponsors appear on at least one study for this condition label.

  3. Typical Venous Ulcer enrolment sits around 140 participants.

    Median target enrolment is 140 among the 12 trials that report a genuine target (sentinel values excluded). 4 of those (33.3%) plan for fewer than 100 participants.

  4. Venous Ulcer research is mostly interventional.

    9 interventional and 3 observational studies make up this index (75% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 21Phase 32Phase 42

Open and recent trials

12 total, page 1 of 1

RECRUITING Phase 3 312 participants

Tissue Repair Gel in Venous Leg Ulcers in AU/US

TR Therapeutics

NCT06707103

RECRUITING Phase 3 312 participants

Tissue Repair Gel in Venous Leg Ulcers (US)

TR Therapeutics

NCT06707090

RECRUITING NA 165 participants

The GORE® VIABAHN® FORTEGRA Venous Stent Iliofemoral Study

W.L.Gore & Associates

NCT05489588

RECRUITING 150 participants

Evaluating the Durability of Closure for Venous Leg Ulcers

Kerecis

NCT06697925

RECRUITING Phase 4 50 participants

A Multicenter, Prospective, Controlled Modified Multi-Platform Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers.

BioLab Holdings

NCT07364630

ACTIVE NOT RECRUITING NA 112 participants

The GORE® VIABAHN® FORTEGRA Venous Stent IVC Study

W.L.Gore & Associates

NCT05409976

COMPLETED 310 participants

The RESPOND Registry

Organogenesis

NCT03286452

COMPLETED Phase 2 140 participants

Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer Recurrence

Medical University of South Carolina

NCT02626156

COMPLETED 100 participants

PuraPly™ Antimicrobial Wound Matrix and Wound Management

Organogenesis

NCT03070938

COMPLETED NA 50 participants

Effectiveness of XCell on Autolytic Debridement of Venous Ulcers

Xylos Corporation

NCT00446823

COMPLETED Phase 4 30 participants

A Post Marketing Study of Apligraf in Non-healing Wounds of Subjects With Venous Leg Ulcers

Organogenesis

NCT01327937

COMPLETED NA 28 participants

Evaluation of a Dual Action Pneumatic Compression System: Tolerance and Comfort in Patients With Venous Leg Ulcers (VLUs)

Tactile Medical

NCT02395302

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 3 2
Phase 4 2

Top Sponsors

Named interventions

Most-linked intervention names on Venous Ulcer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

PuraPly™ Antimicrobial Wound Matrix Device
2 trials
GORE® VIAFORT Vascular Stent Device
2 trials
TR987 0.1% gel + Standard of Care Drug
2 trials
Standard of care Other
2 trials
Dual Action Pneumatic Compression Device
1 trials
Standard of Care Dressing Group Other
1 trials
Apligraf Device
1 trials
Cooling cotton pack Device
1 trials

US sites by state

Facility locations filed on Venous Ulcer trials. A trial with sites in several states counts in each.

New York 7 trials
Florida 6 trials
Pennsylvania 4 trials
California 4 trials
New Jersey 3 trials
North Carolina 3 trials
Michigan 3 trials
Massachusetts 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Venous Ulcer page

12 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 5 Venous Ulcer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Organogenesis sponsors the most Venous Ulcer trials on record, review their full trial history before evaluating a specific study. See Organogenesis's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Venous Ulcer condition card totals 12 registered trials; most-linked intervention PuraPly™ Antimicrobial Wound Matrix; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.