Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
SLE (Systemic Lupus): early-phase trial registry
4 of 7 indexed SLE (Systemic Lupus) trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,497 of 28,707 conditions by registered trial count.
7 US clinical trials · 4 currently recruiting · #2,497 of 28,707 conditions by registered trial count
SLE (Systemic Lupus): 7 US clinical trials tracked, 4 recruiting.
SLE (Systemic Lupus) is the subject of 7 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Cugene, running 1 of these trials.
Enrollment posture brief
Registry condition sle-systemic-lupus
OPEN 4 | RECR 57% | LATE 0 | EARLY 6 | RANK #2497 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Adverse Childhood Experiences (57% recruiting · 14 trials)
SLE (Systemic Lupus) lists 4 open slots (57% of 7 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for SLE (Systemic Lupus) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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SLE (Systemic Lupus) is recruiting above its size-band peers.
4 of 7 indexed trials (57.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of SLE (Systemic Lupus) trials is spread across many organizations.
Cugene accounts for 1 of 7 trials (14.3%). 7 distinct sponsors appear on at least one study for this condition label.
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Most SLE (Systemic Lupus) trials plan to enrol fewer than 100 people.
Median target enrolment is 24 among the 7 trials that report a genuine target (sentinel values excluded). 7 of those (100%) plan for fewer than 100 participants.
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SLE (Systemic Lupus) research is mostly interventional.
7 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
7 total, page 1 of 1
A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease
CRISPR Therapeutics
NCT06925542
Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA
Neutrolis
NCT07237659
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus
Cullinan Therapeutics
NCT06613360
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus Erythematosus
Ventus Therapeutics U.S.
NCT07260877
A Study in Participants With Mild-to-moderate Systemic Lupus Erythematosus
Cugene
NCT05866861
A Multi-component, Person-centered, and Yoga-based Coaching Program for Lupus Chronic Pain
University of Michigan
NCT07196072
Study Evaluating SC291 in Subjects With Severe r/r B-cell Mediated Autoimmune Diseases (GLEAM)
Sana Biotechnology
NCT06294236
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on SLE (Systemic Lupus) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on SLE (Systemic Lupus) trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this SLE (Systemic Lupus) page
7 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 4 SLE (Systemic Lupus) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Cugene sponsors the most SLE (Systemic Lupus) trials on record, review their full trial history before evaluating a specific study. See Cugene's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This SLE (Systemic Lupus) condition card totals 7 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.