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NCT06613360 · ClinicalTrials.gov registry record · Phase 1
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus
A Phase 1 study of SLE and SLE (Systemic Lupus), sponsored by Cullinan Therapeutics.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
- 15
- Study locations
NCT06613360: Recruiting Phase 1 study of SLE and SLE (Systemic Lupus), sponsored by Cullinan Therapeutics.
NCT06613360 is a Phase 1 study of SLE and SLE (Systemic Lupus) that is actively recruiting participants, run by Cullinan Therapeutics. The registered enrollment target is 24 participants, below the 87-participant average among 9 other SLE trials with a reported enrollment target (72% lower). The trial reports 15 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06613360, a Phase 1 study of SLE and SLE (Systemic Lupus), is actively recruiting participants, sponsored by Cullinan Therapeutics.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
- 15
- Study locations
Study Summary
Phase 1b, open-label study of CLN-978 administered subcutaneously in patients with Moderate to Severe Systemic Lupus Erythematosus (SLE).
Primary Outcome
Incidence and severity of adverse events (AEs)/adverse events of special interest (AESIs)/serious adverse events (SAEs)
Conditions Studied
Interventions
- DRUG CLN-978
Study Locations (15)
Other
- Cullinan Investigative Site - Victoria Park
- Arensia Research Clinic - Sofia
- Arensia Research Clinic - Tbilisi
- Arensia Research Clinic - Chisinau
Arizona
- Cullinan Investigative Site - Avondale
- Cullinan Investigative Site - Tucson
New York
- Cullinan Investigative Site - New York
- Cullinan Investigative Site - Rochester
Texas
- Cullinan Investigative Site - Plano
- Cullinan Investigative Site - Webster
Florida
- Cullinan Investigative Site - Orlando
Iowa
- Cullinan Investigative Site - Iowa City
Tennessee
- Cullinan Investigative Site - Memphis
Utah
- Cullinan Investigative Site - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2025-01-21 |
| Est. Completion | 2027-12 |
| Phase | Phase 1 |
What NCT06613360 shows while recruiting
NCT06613360 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 87-participant average among 9 other SLE trials with a reported enrollment target (72% lower).
The record links to 2 conditions, with SLE appearing as the primary indexed condition, and to 1 intervention - of which CLN-978 is the first listed.
NCT06613360 lists 15 locations in 9 states (Other, Arizona, New York).
Frequently Asked Questions
What is clinical trial NCT06613360 about?
NCT06613360 is a clinical study titled "A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus". Phase 1b, open-label study of CLN-978 administered subcutaneously in patients with Moderate to Severe Systemic Lupus Erythematosus (SLE).
What is the current status of trial NCT06613360?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2025-01-21. Estimated completion is 2027-12.
What conditions does trial NCT06613360 study?
This clinical trial studies the following conditions: SLE, SLE (Systemic Lupus).
What interventions are being tested in trial NCT06613360?
The interventions under investigation include: CLN-978 (DRUG).
Who is sponsoring clinical trial NCT06613360?
This trial is sponsored by Cullinan Therapeutics, which has 9 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06613360 being conducted?
This trial has 15 study locations across Arizona, Florida, Iowa, New York, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for SLE
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06613360's enrollment target sits among peer trials
24 7th of 9 higher than 1 of 9 other SLE trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other SLE trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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