Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
SLE: early-phase trial registry
5 of 10 indexed SLE trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,724 of 28,707 conditions by registered trial count.
10 US clinical trials · 5 currently recruiting · #1,724 of 28,707 conditions by registered trial count
SLE: 10 US clinical trials tracked, 5 recruiting.
SLE is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Stacy Ardoin MD, running 1 of these trials.
Enrollment posture brief
Registry condition sle
OPEN 5 | RECR 50% | LATE 0 | EARLY 8 | RANK #1724 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)
SLE lists 5 open slots (50% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for SLE on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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SLE is recruiting above its size-band peers.
5 of 10 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of SLE trials is spread across many organizations.
Stacy Ardoin MD accounts for 1 of 10 trials (10%). 10 distinct sponsors appear on at least one study for this condition label.
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Most SLE trials plan to enrol fewer than 100 people.
Median target enrolment is 51 among the 10 trials that report a genuine target (sentinel values excluded). 8 of those (80%) plan for fewer than 100 participants.
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SLE research is mostly interventional.
9 interventional and 1 observational studies make up this index (90% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
10 total, page 1 of 1
Safety and Efficacy of ONT01 in Lupus
Hospital for Special Surgery, New York
NCT07107659
CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus
Children's Hospital of Philadelphia
NCT06839976
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus
Cullinan Therapeutics
NCT06613360
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus Erythematosus
Ventus Therapeutics U.S.
NCT07260877
UC-MSC Cell Therapy Study for Systemic Lupus Erythematosus (SLE) Patients
LiveKidney.Bio
NCT06737380
Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus
Alumis
NCT05966480
Vaccine Hesitancy in Black/African Americans With Rheumatic Diseases
Northwestern University
NCT05822219
AB-101 in Combination With B-Cell Depleting mAb in Patients Who Failed Treatment for Class III or IV Lupus Nephritis or Other Forms of Refractory Systemic Lupus Erythematosus
Artiva Biotherapeutics
NCT06265220
Myocardial Inflammation in Systemic Lupus Erythematosus
Stacy Ardoin MD
NCT01761422
JBT-101 in Systemic Lupus Erythematosus (SLE)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03093402
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on SLE records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on SLE trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this SLE page
10 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 SLE trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Stacy Ardoin MD sponsors the most SLE trials on record, review their full trial history before evaluating a specific study. See Stacy Ardoin MD's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This SLE condition card totals 10 registered trials; most-linked intervention Placebo; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.