Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov official registry

Skin Aging clinical trials

All 10 indexed Skin Aging trials have closed enrollment.

10 US clinical trials ·

Skin Aging is the subject of 10 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 2 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Victoria Collotta, running 2 of these trials.

The research picture

Skin Aging has 10 registered US clinical trials; none are currently listed as recruiting, so most are completed or in follow-up.

0
recruiting participants now
0%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
2
top sponsor: Victoria Collotta
Phase 11Phase 31Phase 41

Active & Recent Trials

10 total, page 1 of 1

ACTIVE NOT RECRUITING NA 40 participants

A Clinical Study to Evaluate the Efficacy of Activated Silk™ 27P-α in Subjects, Aged 35-65 Years of Age, to Improve the Signs of Aging

Victoria Collotta

NCT06804759

ACTIVE NOT RECRUITING NA 15 participants

A Clinical Study to Evaluate the Efficacy of Activated Silk™ 27P-α in Subjects, Aged 35-65 Years of Age, to Improve the Signs of Aging, by Comparing to a Placebo

Victoria Collotta

NCT06804772

ACTIVE NOT RECRUITING Early Phase 1 12 participants

Effect of Topical Sulforaphane on Skin Aging and With Ultraviolet and Visible Light Exposure

Johns Hopkins University

NCT03730649

COMPLETED Phase 3 247 participants

Efficacy and Safety Study of Botulinum Toxin Type A for Moderate to Severe Crow's Feet Lines

Revance Therapeutics

NCT01776606

COMPLETED NA 156 participants

Relationship of Skin Related SNP to Topical Skin Care Product

HelicalCodeMD

NCT03446079

COMPLETED NA 63 participants

Efficacy of a Dietary Supplement on Parameters of Skin Aging in Men and Women

Natals, Inc. dba Ritual

NCT06083402

COMPLETED NA 50 participants

Thermage CPT for Treatment of Facial and Neck Laxity

Valeant Pharmaceuticals

NCT01783496

COMPLETED Phase 4 45 participants

Clinical Evaluation of Day and Night Skin Care Creams Supplemented With MediCell Technology (MCT)'s Composition of Defensins and Supportive Molecules

Advanced Dermatology

NCT02765763

COMPLETED NA 33 participants

Clinical Trial to Evaluate the Efficacy of Skin Products to Improve Skin Quality and Health

Truology

NCT06853899

COMPLETED NA 18 participants

A Proof of Concept Study to Evaluate the Efficacy and Tolerability of Skinpen on Male and Female Subjects' Dorsal Hands as a Treatment of Hand Aging

Crown Laboratories

NCT05030051

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Skin Aging Trial Landscape

10 indexed Skin Aging studies · 0 recruiting (0%).

Phase mix: 2 late (III/IV) vs 1 early (I/II).

Top sponsor: Victoria Collotta (2 trials), 8 others listed. 10 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Skin Aging?

PlainTrial tracks 10 US clinical trials for Skin Aging, of which 0 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Skin Aging?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.