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NCT03730649 · ClinicalTrials.gov registry record · Early Phase 1
Effect of Topical Sulforaphane on Skin Aging and With Ultraviolet and Visible Light Exposure
A Early Phase 1 study of Skin Aging, sponsored by Johns Hopkins University.
- Active
- Registry status
- Early Phase 1
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT03730649: Active Early Phase 1 study of Skin Aging, sponsored by Johns Hopkins University.
NCT03730649 is a Early Phase 1 study of Skin Aging that is active but no longer recruiting, run by Johns Hopkins University. The registered enrollment target is 12 participants, below the 74-participant average among 9 other Skin Aging trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03730649, a Early Phase 1 study of Skin Aging, is active but no longer recruiting, sponsored by Johns Hopkins University.
- ACTIVE NOT RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
The study is to compare the expression of both keratin 16 and 17 before and after application of sulforaphane on both photoprotected and photoexposed area, and to determine whether these findings alter skin aging as well as skin response to ultraviolet (UV) and visible light exposure.
Primary Outcome
The investigators will detect the presence of keratin 16 in the basal layer of the epidermis in both photoprotected and photodamaged skin treated with sulforaphane (SF), by immunofluorescence assay, to determine whether SF can improve skin fragility and other features seen in these conditions
Conditions Studied
Interventions
- DRUG Sulforaphane (broccoli sprout extract)
- RADIATION UV or visible light
Study Locations (1)
Maryland
- Cutaneous Translational Research Program, Department of Dermatology, Johns Hopkins University School of Medicine - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2019-10-09 |
| Est. Completion | 2026-10 |
| Phase | Early Phase 1 |
What the registry record for NCT03730649 still lists
NCT03730649 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 74-participant average among 9 other Skin Aging trials with a reported enrollment target (84% lower).
The record links to 1 condition, with Skin Aging appearing as the primary indexed condition, and to 2 interventions - of which Sulforaphane (broccoli sprout extract) is the first listed.
NCT03730649 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT03730649 about?
NCT03730649 is a clinical study titled "Effect of Topical Sulforaphane on Skin Aging and With Ultraviolet and Visible Light Exposure". The study is to compare the expression of both keratin 16 and 17 before and after application of sulforaphane on both photoprotected and photoexposed area, and to determine whether these findings alter skin aging as well as skin response to ultraviolet (UV) and visible light exposure.
What is the current status of trial NCT03730649?
This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 12 participants. The study started on 2019-10-09. Estimated completion is 2026-10.
What conditions does trial NCT03730649 study?
This clinical trial studies the following conditions: Skin Aging.
What interventions are being tested in trial NCT03730649?
The interventions under investigation include: Sulforaphane (broccoli sprout extract) (DRUG), UV or visible light (RADIATION).
Who is sponsoring clinical trial NCT03730649?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03730649 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03730649's enrollment target sits among peer trials
12 10th of 9 the lowest of 9 other Skin Aging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Skin Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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