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NCT07154147 · ClinicalTrials.gov registry record · Phase 4

Oral vs IV Sedation for Cataract Surgery in Older Adults

A Phase 4 study of Older Adults and Sedation, sponsored by University of California, San Francisco.

Recruiting
Registry status
Phase 4
Development phase
20
Enrollment target
1
Study location

NCT07154147: Recruiting Phase 4 study of Older Adults and Sedation, sponsored by University of California, San Francisco.

NCT07154147 is a Phase 4 study of Older Adults and Sedation that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 20 participants, below the 224-participant average among 23 other Older Adults trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07154147, a Phase 4 study of Older Adults and Sedation, is actively recruiting participants, sponsored by University of California, San Francisco.

RECRUITING
Registry status
Phase 4
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to find out if taking a pill (oral sedation) works just as well as getting medicine through a vein (IV sedation) to help older adults feel relaxed during cataract surgery. We are also studying how these two methods affect recovery, especially thinking and memory after surgery, and how satisfied people are with their care. Participants in this study will be randomly assigned to receive either oral sedation (+ IV placebo) or IV sedation (+ oral placebo) before their cataract surgery. They will complete short surveys about their thinking and recovery before and after surgery, and will be contacted by phone after surgery to check on their recovery. The results of this study will help doctors understand if a simple pill can be a safe and effective alternative to IV sedation for cataract surgery.

Primary Outcome

Feasibility, completeness, and distribution of cognitive recovery data will be assessed using the cognitive domain of the Postoperative Quality of Recovery Scale (PQRS), a validated questionnaire assessing recovery across multiple health domains. Feasibility outcomes include the proportion of participants with assessable PQRS cognitive data at each time point and the distribution of recovered versus not recovered classifications. Cognitive recovery is defined by meeting pre-specified criteria fo

Conditions Studied

Older Adults Sedation Cataract Surgery Perioperative Care Cognition Function

Interventions

  • DRUG Alprazolam
  • DRUG Midazolam

Study Locations (1)

California

  • UCSF Wayne and Gladys Valley Center for Vision, Mission Bay - San Francisco

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2025-08-12
Est. Completion 2025-11
Phase Phase 4
University of California, San Francisco

1,713 total trials

What NCT07154147 shows while recruiting

NCT07154147 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 224-participant average among 23 other Older Adults trials with a reported enrollment target (91% lower).

The record links to 5 conditions, with Older Adults appearing as the primary indexed condition, and to 2 interventions - of which Alprazolam is the first listed.

NCT07154147 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT07154147 about?

NCT07154147 is a clinical study titled "Oral vs IV Sedation for Cataract Surgery in Older Adults". The goal of this clinical trial is to find out if taking a pill (oral sedation) works just as well as getting medicine through a vein (IV sedation) to help older adults feel relaxed during cataract surgery. We are also studying how these two methods affect recovery, especially thinking and memory af...

What is the current status of trial NCT07154147?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 20 participants. The study started on 2025-08-12. Estimated completion is 2025-11.

What conditions does trial NCT07154147 study?

This clinical trial studies the following conditions: Older Adults, Sedation, Cataract Surgery, Perioperative Care, Cognition Function.

What interventions are being tested in trial NCT07154147?

The interventions under investigation include: Alprazolam (DRUG), Midazolam (DRUG).

Who is sponsoring clinical trial NCT07154147?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07154147 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Older Adults

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07154147's enrollment target sits among peer trials

20 19th of 23 higher than 3 of 23 other Older Adults trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Older Adults trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT07154147

Source: ClinicalTrials.gov NCT07154147, the US trial registry maintained by the National Library of Medicine. NCT07154147 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.