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Refractory Epilepsy: early-phase trial registry
5 of 6 indexed Refractory Epilepsy trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,866 of 28,707 conditions by registered trial count.
6 US clinical trials · 5 currently recruiting · #2,866 of 28,707 conditions by registered trial count
Refractory Epilepsy: 6 US clinical trials tracked, 5 recruiting.
Refractory Epilepsy is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is SK Life Science, running 1 of these trials.
Enrollment posture brief
Registry condition refractory-epilepsy
OPEN 5 | RECR 83% | LATE 0 | EARLY 3 | RANK #2866 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Alcoholic Hepatitis (83% recruiting · 6 trials)
Refractory Epilepsy lists 5 open slots (83% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Refractory Epilepsy on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Refractory Epilepsy is recruiting above its size-band peers.
5 of 6 indexed trials (83.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Refractory Epilepsy research.
SK Life Science accounts for 1 of 6 trials (16.7%). 6 distinct sponsors appear on at least one study for this condition label.
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Most Refractory Epilepsy trials plan to enrol fewer than 100 people.
Median target enrolment is 24 among the 5 trials that report a genuine target (sentinel values excluded). 4 of those (80%) plan for fewer than 100 participants.
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Refractory Epilepsy research is mostly interventional.
6 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
6 total, page 1 of 1
Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy
Neuroelectrics Corporation
NCT04770337
Optimal Stimulation Parameters to Disrupt Epileptiform Activity
Massachusetts General Hospital
NCT06141668
Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application
Dartmouth-Hitchcock Medical Center
NCT06425029
Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy
University of Minnesota
NCT05493722
The Efficacy of a Subanesthetic Doses of IV Ketamine in the Treatment Drug Resistant Epilepsy
Madeline Fields
NCT05019885
Safety and Efficacy of 333369 in the Treatment of Partial Epilepsy
SK Life Science
NCT00228969
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Refractory Epilepsy records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Refractory Epilepsy trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Refractory Epilepsy page
6 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 Refractory Epilepsy trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- SK Life Science sponsors the most Refractory Epilepsy trials on record, review their full trial history before evaluating a specific study. See SK Life Science's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Refractory Epilepsy condition card totals 6 registered trials; most-linked intervention RWJ-333369; top US site state Minnesota. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.