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ClinicalTrials.gov 2 recruiting now official registry

Refractive Errors clinical trials

Every US clinical trial registered for Refractive Errors — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

15 US clinical trials · 2 currently recruiting

The research picture

Refractive Errors has 15 registered US clinical trials, 2 of them open to new participants right now — about 13% of the total.

2
recruiting participants now
13%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
9
top sponsor: Alcon Research

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 60 participants

Corneal Elastography and Patient Specific Modeling

The Cleveland Clinic

NCT03030755

RECRUITING 33 participants

To Study the Effects of Refractive Surgery on OCT Measurements in the Eye

University of Nebraska

NCT05856786

COMPLETED NA 323 participants

Clinical Assessment of a HYDRAGLYDE® Regimen

Alcon, a Novartis Company

NCT03026257

COMPLETED 312 participants

Air Optix Daily Wear Contact Lenses

Alcon Research

NCT05827224

COMPLETED NA 188 participants

Assessing Fitting Guides in Alcon Multifocal Contact Lenses

Alcon Research

NCT03118934

COMPLETED NA 112 participants

Clinical Performance of Two Commercial, Daily Disposable Contact Lenses

Alcon Research

NCT05010512

COMPLETED NA 107 participants

DD T2 Daily Disposable Registration Trial

Alcon Research

NCT03305770

COMPLETED NA 92 participants

Investigation of the Accuracy of an Automated Refractor to Provide Well-tolerated Eyeglass Prescriptions

PlenOptika

NCT06883032

COMPLETED NA 88 participants

Clinical Performance of a Monthly Replacement Silicone Hydrogel Lens

Alcon Research

NCT03586167

COMPLETED Phase 2 68 participants

Evaluation of the Safety and Effectiveness of Aceclidine/Brimonidine (LNZ101) and Aceclidine (LNZ100) in the Treatment of Presbyopia

LENZ Therapeutics

NCT05294328

COMPLETED NA 39 participants

Clinical Characterization of an Investigational Frequent Replacement Daily Wear Silicone Hydrogel Sphere Contact Lens

Alcon Research

NCT04702984

COMPLETED NA 36 participants

Three Daily Wear Monthly Replacement Silicone Hydrogel Contact Lenses With Two Multi-purpose Disinfecting Solution Combinations

Alcon Research

NCT04789382

COMPLETED NA 18 participants

Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses

Alcon Research

NCT05886907

COMPLETED NA 12 participants

Clinical Performance of a Silicone Hydrogel Contact Lens Following One Night of Extended Wear

Alcon Research

NCT03560141

COMPLETED 10 participants

Early Feasibility Study to Evaluate the AccuraSee in Correcting Residual Refractive Errors After Cataract Surgery

OnPoint Vision

NCT05113979

Phase Distribution

PhaseTrial count
Phase 2 1

Top Sponsors

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Refractive Errors Trial Landscape

ClinicalTrials.gov lists 15 US studies indexed under Refractive Errors, and 2 of those are currently open to recruitment — roughly 13% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Refractive Errors shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Refractive Errors is led by Alcon Research with 9 indexed trials, alongside 6 other organizations in the top contributor list. The list on this page surfaces up to 15 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Refractive Errors?

PlainTrial tracks 15 US clinical trials for Refractive Errors, of which 2 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Refractive Errors?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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