Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Prosthetic-joint Infection: early-phase trial registry
4 of 10 indexed Prosthetic-joint Infection trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,724 of 28,707 conditions by registered trial count.
10 US clinical trials · 4 currently recruiting · #1,724 of 28,707 conditions by registered trial count
Prosthetic-joint Infection: 10 US clinical trials tracked, 4 recruiting.
Prosthetic-joint Infection is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Osteal Therapeutics, running 2 of these trials.
Enrollment posture brief
Registry condition prosthetic-joint-infection
OPEN 4 | RECR 40% | LATE 2 | EARLY 4 | RANK #1724 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Acute Myeloid Leukemia (AML) (40% recruiting · 30 trials)
Prosthetic-joint Infection lists 4 open slots (40% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Prosthetic-joint Infection on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Prosthetic-joint Infection is recruiting below its size-band peers.
4 of 10 indexed trials (40%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Prosthetic-joint Infection research.
Osteal Therapeutics accounts for 2 of 10 trials (20%). 8 distinct sponsors appear on at least one study for this condition label.
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Most Prosthetic-joint Infection trials plan to enrol fewer than 100 people.
Median target enrolment is 76 among the 10 trials that report a genuine target (sentinel values excluded). 7 of those (70%) plan for fewer than 100 participants.
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Prosthetic-joint Infection research is mostly interventional.
10 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
10 total, page 1 of 1
Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty
Peptilogics
NCT07214311
Real-component Vs All-cement Articulating Spacers for Periprosthetic Knee Infection
Northwestern University
NCT06293352
The Effect of Peri-Operative Adjunctive Probiotics on Immunological Markers in Cases of Prosthetic Joint Infection of the Hip and Knee
NYU Langone Health
NCT06919913
Reduction of Bacterial Seeding in Total Shoulder Arthroplasty
St. Louis University
NCT07406893
Study of Antibiotic Spacer Design to Treat Infection After Hip Replacement
Rush University Medical Center
NCT01373099
A Second Trial of the Abbreviated Protocol Two-Stage Exchange
Osteal Therapeutics
NCT05607030
SURGX Antimicrobial Gel Versus Povidone-iodine Skin Incision Prep in Total Shoulder Arthroplasty
St. Louis University
NCT05919888
Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections
Infectious Diseases Physicians
NCT03426761
Safety and Efficacy in Patients Treated for Hip or Knee PJI With Vancomycin and Tobramycin Joint Irrigation
Osteal Therapeutics
NCT03721328
Tissue Distribution, Pharmacokinetics, Safety, and Tolerability After a Single Dose of TNP-2092 in Participants Undergoing Primary Total Hip or Knee Arthroplasty
TenNor Therapeutics Limited
NCT04294862
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 3 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Prosthetic-joint Infection records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Prosthetic-joint Infection trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Prosthetic-joint Infection page
10 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 4 Prosthetic-joint Infection trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Osteal Therapeutics sponsors the most Prosthetic-joint Infection trials on record, review their full trial history before evaluating a specific study. See Osteal Therapeutics's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Prosthetic-joint Infection condition card totals 10 registered trials; most-linked intervention SURGX Wound Gel; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.