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ClinicalTrials.gov 7 recruiting now early-phase tilt small index

Prostatic Neoplasms, Castration-Resistant: early-phase trial registry

7 of 11 indexed Prostatic Neoplasms, Castration-Resistant trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 7 currently recruiting · #1,577 of 28,707 conditions by registered trial count

Prostatic Neoplasms, Castration-Resistant: 11 US clinical trials tracked, 7 recruiting.

Prostatic Neoplasms, Castration-Resistant is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is Janssen Research & Development, running 2 of these trials.

Enrollment posture brief

Registry condition prostatic-neoplasms-castration-resistant

OPEN 7 | RECR 64% | LATE 2 | EARLY 7 | RANK #1577 | SPON 2

Nearest open-share peer: Advanced Melanoma (64% recruiting · 22 trials)

Acute Pancreatitis81.8%Prostatic Neoplasms, Cas (th…64%Acute Stroke45.5%Acquired Brain Injury36.4%Acute Lung Injury9.1%
Open-enrollment share among volume-matched conditions near Prostatic Neoplasms, Castration-Resistant

Prostatic Neoplasms, Castration-Resistant lists 7 open slots (64% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Prostatic Neoplasms, Castration-Resistant on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Prostatic Neoplasms, Castration-Resistant is recruiting above its size-band peers.

    7 of 11 indexed trials (63.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Prostatic Neoplasms, Castration-Resistant research.

    Janssen Research & Development accounts for 2 of 11 trials (18.2%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical Prostatic Neoplasms, Castration-Resistant enrolment sits around 136 participants.

    Median target enrolment is 136 among the 11 trials that report a genuine target (sentinel values excluded). 4 of those (36.4%) plan for fewer than 100 participants.

  4. Prostatic Neoplasms, Castration-Resistant research is mostly interventional.

    9 interventional and 2 observational studies make up this index (81.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 21Phase 31Phase 41

Open and recent trials

11 total, page 1 of 1

RECRUITING Phase 3 800 participants

A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

Janssen Research & Development

NCT07225946

RECRUITING Phase 1 275 participants

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

Novartis Pharmaceuticals

NCT04104776

RECRUITING Phase 1 220 participants

Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)

Merck Sharp & Dohme

NCT06353386

RECRUITING Phase 1 54 participants

64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE)

Clarity Pharmaceuticals

NCT04868604

RECRUITING Phase 1 54 participants

Gedatolisib in Combination With Darolutamide in Metastatic Castration-Resistant Prostate Cancer

Celcuity

NCT06190899

RECRUITING Phase 1 30 participants

Study of TVB-2640 in Men With Metastatic Castration-Resistant Prostate Cancer

Weill Medical College of Cornell University

NCT05743621

RECRUITING Phase 4 15 participants

18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy in Patients With Prostate Cancer

VA Greater Los Angeles Healthcare System

NCT06706921

ACTIVE NOT RECRUITING Phase 2 136 participants

A Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate Cancer

Janssen Research & Development

NCT03431350

COMPLETED 5,506 participants

Enzalutamide vs. Abiraterone in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer (mCRPC)

Pfizer

NCT05520138

COMPLETED 200 participants

Navigant Study- Treatment Patterns in mCRPC (Metastatic Castrate Resistant Prostate Cancer )

Bayer

NCT02899104

COMPLETED Phase 1 120 participants

BI836845 Plus Enzalutamide in Castrate Resistant Prostate Cancer (CRPC)

Boehringer Ingelheim

NCT02204072

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 1
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Prostatic Neoplasms, Castration-Resistant records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Enzalutamide Drug
4 trials
Docetaxel Drug
2 trials
BI 836845 Drug
1 trials
Xofigo (Radium-223 dichloride, BAY88-8223) Drug
1 trials
Abiraterone acetate 1000 mg Drug
1 trials
Cetrelimab 480 mg Drug
1 trials
Cetrelimab 240 mg Drug
1 trials
Niraparib 200 mg Drug
1 trials

US sites by state

Facility locations filed on Prostatic Neoplasms, Castration-Resistant trials. A trial with sites in several states counts in each.

New York 6 trials
Michigan 6 trials
New Jersey 4 trials
California 4 trials
Texas 3 trials
Pennsylvania 3 trials
Maryland 3 trials
Wisconsin 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Prostatic Neoplasms, Castration-Resistant page

11 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 7 Prostatic Neoplasms, Castration-Resistant trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Janssen Research & Development sponsors the most Prostatic Neoplasms, Castration-Resistant trials on record, review their full trial history before evaluating a specific study. See Janssen Research & Development's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Prostatic Neoplasms, Castration-Resistant condition card totals 11 registered trials; most-linked intervention Enzalutamide; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.