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NCT05520138 · ClinicalTrials.gov registry record

Enzalutamide vs. Abiraterone in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer (mCRPC)

A clinical trial of Prostatic Neoplasms, Castration-Resistant, sponsored by Pfizer.

Completed
Registry status
5,506
Enrollment target
1
Study location

NCT05520138 is a study of Prostatic Neoplasms, Castration-Resistant that has completed, run by Pfizer. The registered enrollment target is 5,506 participants, above the 190-participant average among 10 other Prostatic Neoplasms, Castration-Resistant trials with a reported enrollment target (2798% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT05520138, a study of Prostatic Neoplasms, Castration-Resistant, has completed, sponsored by Pfizer.

COMPLETED
Registry status
5,506 participants
Enrollment target
1
Study location

Study Summary

This study will be a retrospective data analysis to compare outcomes between patients with chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC) who initiated enzalutamide and those who initiated abiraterone using the 100% Fee-For-Service Medicare claims data. The study will address the following objectives: Primary objective: To compare overall survival (OS) in patients with chemotherapy-naïve mCRPC who initiated enzalutamide vs. abiraterone Secondary objectives: * To compare OS in patients with chemotherapy-naïve mCRPC who received only enzalutamide without any subsequent therapy vs. abiraterone without any subsequent therapy * To compare treatment duration and time to subsequent therapy in chemotherapy-naïve mCRPC patients initiating enzalutamide vs. abiraterone

Interventions

  • DRUG Enzalutamide
  • DRUG Abiraterone acetate

Study Locations (1)

New York

  • Pfizer Inc - New York

Trial Details

FieldValue
Enrollment Target 5,506 participants
Start Date 2022-08-29
Est. Completion 2023-06-30

Sponsor

Pfizer

1,845 total trials

What the Registry Record Tells You About NCT05520138

The ClinicalTrials.gov registry entry for NCT05520138 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 5,506 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 190-participant average among 10 other Prostatic Neoplasms, Castration-Resistant trials with a reported enrollment target (2798% higher). The listed sponsor is Pfizer, which has 1,845 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Prostatic Neoplasms, Castration-Resistant appearing as the primary indexed condition, and to 2 interventions - of which Enzalutamide is the first listed.

NCT05520138 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT05520138 about?

NCT05520138 is a clinical study titled "Enzalutamide vs. Abiraterone in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer (mCRPC)". This study will be a retrospective data analysis to compare outcomes between patients with chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC) who initiated enzalutamide and those who initiated abiraterone using the 100% Fee-For-Service Medicare claims data. The study will add...

What is the current status of trial NCT05520138?

This trial is currently completed. The enrollment target is 5,506 participants. The study started on 2022-08-29. Estimated completion is 2023-06-30.

What conditions does trial NCT05520138 study?

This clinical trial studies the following conditions: Prostatic Neoplasms, Castration-Resistant.

What interventions are being tested in trial NCT05520138?

The interventions under investigation include: Enzalutamide (DRUG), Abiraterone acetate (DRUG).

Who is sponsoring clinical trial NCT05520138?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05520138 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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